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个人简介

Dr. Anthony Cammarato is an Assistant Professor of Medicine in the Cardiology and Physiology Departments. He studies the identification and manipulation of age- and mutation-dependent modifiers of cardiac function, hierarchical modeling and imaging of contractile machinery, integrative analysis of striated muscle performance and myopathic processes. Dr. Cammarato holds a bachelor’s degree in Biology from Mary Washington College and a PhD, in Physiology and Biophysics, from the Boston University School of Medicine. He completed a postdoctoral fellowship at San Diego State University and worked as a staff scientist and later as an assistant research professor at the Sanford-Burnham Medical Research Institute before joining the Johns Hopkins faculty in 2011. He is a member of the American Physiological Society, the Biophysical Society, the American Society for Cell Biology and the Genetics Society of America. B.S., Mary Washington College (Virginia) (1995) Ph.D., Boston University (Massachusetts) (2003)

研究领域

Myopathic processes; Integrative analysis of striated muscle performance; Hierarchical modeling and imaging of contractile

近期论文

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Nishimura M, Kumsta C, Kaushik G, Diop SB, Ding Y, Bisharat-Kernizan J, Catan H, Cammarato A, Ross RS, Engler AJ, Bodmer R, Hansen M, Ocorr K. A dual role for integrin-linked kinase and β1-integrin in modulating cardiac aging. Aging Cell. 2014 Jan 9. doi: 10.1111/acel.12193. [Epub ahead of print] Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Circ Res. 2014 Jan 17;114(2):e6-17. doi: 10.1161/CIRCRESAHA.114.302028. Epub 2013 Nov 12. Erratum in: Circ Res. 2014 Feb 14;114(4):e28. Xie HB, Cammarato A, Rajasekaran NS, Zhang H, Suggs JA, Lin HC, Bernstein SI, Benjamin IJ, Golic KG. The NADPH metabolic network regulates human αB-crystallin cardiomyopathy and reductive stress in Drosophila melanogaster. PLoS Genet. 2013 Jun;9(6):e1003544. doi: 10.1371/journal.pgen.1003544. Epub 2013 Jun 20. Wang Y, Melkani GC, Suggs JA, Melkani A, Kronert WA, Cammarato A, Bernstein SI. Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness. Mol Biol Cell. 2012 Jun;23(11):2057-65. doi: 10.1091/mbc.E12-02-0120. Epub 2012 Apr 11. Kaushik G, Fuhrmann A, Cammarato A, Engler AJ. In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium. Biophys J. 2011 Dec 7;101(11):2629-37. doi: 10.1016/j.bpj.2011.10.042.

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