个人简介

Dr. Alan Baer graduated from the Johns Hopkins University School of Medicine in 1978 and completed his post-graduate medical training in Internal Medicine and Rheumatology at the Johns Hopkins and Vanderbilt University Hospitals. He was a faculty member at the University at Buffalo, State University of New York, from 1986 to 2007, and served there as Chief of the Section of Rheumatology and Fellowship Program Director. He joined the faculty at Johns Hopkins in 2007 and is currently Associate Professor of Medicine and Director of the Jerome L. Greene Sjogren’s Syndrome Center and the Gout Clinic. Since 2015, he been an Investigator in the Sjogren’s Syndrome Clinic at the National Institutes of Health. He was Chief of Rheumatology and Clinical Director of the Johns Hopkins University Rheumatology Practice at the Good Samaritan Hospital in Baltimore, Maryland from 2007 to 2014. Dr. Baer is currently engaged in a number of research studies in the area of Sjogren’s syndrome. He was the principal investigator of the NIH subcontract to Johns Hopkins to conduct the Sjogren’s International Registry (SICCA) and enrolled 300 patients into the registry. The SICCA registry has been a rich source of clinical data and biospecimens for research that Dr. Baer is conducting with colleagues at both Hopkins and the University of California-San Francisco. He is conducting a longitudinal observational study of patients with Sjogren’s syndrome. He is collaborating with Dr. Ben Larman in the Department of Pathology on a characterization of the complete autoantibody repertoire in patients with Sjogren’s Syndrome using phage immunoprecipation sequencing. MD, Johns Hopkins University School of Medicine (1978)

研究领域

Sjogren's Syndrome; Metabolic Myopathies

Dr. Baer is engaged in a number of research studies in the area of both Sjogren’s syndrome and gout. He was the principal investigator of the NIH subcontract to Johns Hopkins to conduct the Sjogren’s International Registry (SICCA) and enrolled 300 patients into the registry. The SICCA registry was utilized to develop the 2012 ACR classification criteria for Sjogren’s syndrome. It has also been a rich source of clinical data and biospecimens for research that Dr. Baer is conducting with colleagues at both Hopkins and the University of California-San Francisco. He is conducting a longitudinal observational study of patients with Sjogren’s syndrome and is directing a clinical trial of baminercept in Sjogren’s syndrome at Hopkins organized by the Autoimmunity Centers of Excellence. He is collaborating with Dr. Mara McAdams DeMarco (Bloomberg School of Public Health) on epidemiologic studies of gout, using the Atherosclerosis Risk in Communities cohort, and with Dr. John Carrino (Department of Radiology) on the utility of dual energy computed tomography in gout.

近期论文

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Baer AN, McAdams-DeMarco, M, Shiboski S, Lam M, Lanfranchi HE, Yi D, Schiødt M, Umehara H, Srinivasan M, Challacombe S, Shirlaw P, Vivino F, Criswell LA, Shiboski CH. The SSB-positive/SSA-negative antibody profile is not associated with key phenotypic features of Sjögren's syndrome Ann Rheum Dis, 2015 Mar 3. [Epub ahead of print] Baer AN, Petri M, Sohn J, Rosen A, Casciola-Rosen L. Antibodies to interferon-inducible protein-16 in primary Sjögren's syndrome are associated with markers of more severe disease. Arthritis Care Res, in press. Akpek EK, Mathews P, Hahn S, Hessen M, Kim J, Grader-Beck T, Birnbaum J, Baer AN. Ocular and Systemic Morbidity in a Longitudinal Cohort of Sjögren's Syndrome. Ophthalmology 2014; Aug 29. pii: S0161-6420. Hall JC, Baer AN, Shah AA, Criswell LA, Shiboski CH, Rosen A, Casciola-Rosen L, Molecular diagnostics for patient subsetting in Sjogren's syndrome. Arthritis Rheum, in press. Fiorentino DF, Presby M, Baer AN, Christopher-Stine L, Petri M, Rieger KE, Soloski M, Rosen A, Mammen AL, Casciola-Rosen L, PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren's syndrome, Ann Rheum Dis, manuscript in press Baer AN, Kurano T, Thakur U, Thawait GK, Fuld MK, Maynard JW, McAdams DeMarco M, Fishman EK, Carrino JA. Sensitivity of dual-energy computed tomography for non-tophaceous and tophaceous gout. Manuscript under revision Baer AN, Maynard JW, Shaikh F, Magder LS, Petri M. Secondary Sjögren's Syndrome in Systemic Lupus Erythematosus Defines a Distinct Disease Subset. J Rheumatol 2010; 37:1143-9