Aucott, John - Johns Hopkins University

个人简介

Dr. John Aucott is an assistant professor of medicine at the Johns Hopkins University School of Medicine. An internist and Lyme disease expert in the Division of Rheumatology, he is the director of the Johns Hopkins Lyme Disease Clinical Research Center. With more than 15 years of research experience on the crippling effects of Lyme disease, he has published studies focusing on characteristics of early Lyme disease differences in males and females with an emphasis on prospects for prevention, diagnosis and treatment. Dr. Aucott received his medical degree from the Johns Hopkins University School of Medicine. He completed his residency in internal medicine at the University Hospitals of Cleveland. He is fellowship-trained in infectious disease and geographic medicine. Dr. Aucott and his colleagues were recognized by Johns Hopkins with a Discovery Fund Synergy Award in 2014. MD, Johns Hopkins University School of Medicine (1984)

研究领域

Dr. John Aucott and his colleague Dr. Soloski are engaged in a multi-year longitudinal study of patients diagnosed with early-untreated Lyme disease and matched controls, the Study of Lyme disease Immunology and Clinical Events (or SLICE). This has generated a large and unique repository of clinical data and biological samples from patients with a range of clinical outcomes and collected over several seasons. We have recently published on the immune heterogeneity of patients with Lyme disease using samples from this collection. Our goal is to utilize these samples to help identify new biomarkers of Lyme disease that will inform as to disease diagnosis, disease outcome and understand disease pathophysiology. Dr. Aucott’s clinical research site recruits and enrolls participants with untreated early Lyme disease and erythema migrans for these studies. Participants have extensive clinical characterization pre and post-treatment. The Lyme sample biorepository will provide serum samples from this collection for the proposed studies and the clinical study team will as aid in the analysis and interpretation of results.

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Alghaferi MY, Anderson JM, Park J, Auwaerter PG, Aucott JN, Norris DE, Dumler JS. Borrelia burgdorferi Heterogeneity among human and murine isolates from a defined region of northern Maryland and southern Pennsylvania: Lack of correlation with invasive and noninvasive genotypes. J Clin Micro 2005 v43, No 4: 1879-1884. Coulter P, Lema C, Flayhart D, Linhardt AS, Aucott JN, Auwaerter PG, Dumler JS. Two-year Evaluation of Borrelia burgdorferi culture and supplemental tests for definitive diagnosis of Lyme Disease. J Clin Micro 2005 v43, No 10: 5080-5084. Auwaerter, P.G, Aucott, J., & Dumler J.S. (2005). Lyme borreliosis (Lyme disease): molecular and cellular pathobiology and prospects for prevention, diagnosis, and treatment. Expert Reviews in Molecular Medicine, 6(2), 1-22. Morrison, C. Seifter, A., & Aucott, J.N. (2009). Unusual Presentation of Early Disseminated Lyme Disease: Horner's Syndrome and Atypical Rash with Negative Serology. Journal of the American Board of Family Medicine. 22 (2), 219-222. Aucott J, Morrison C, Munoz B, Rowe PC, Schwarzwalder A, West SK. (2009) Diagnostic challenges of early Lyme disease: Lessons from a community case series. BMC Infectious Diseases 9:79. Aucott JN, Rebman AW, Crowder LA, Kortte KB. Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: is there something here? Qual Life Res (2012) DOI 10.1007/s11136-012-0126-6 Eshoo MW, Crowder CC, Rebman AW, Rounds MA, Matthews HE, Picuri JM, Soloski MJ, Ecker DJ, Schutzer SE, Aucott JN. Direct Molecular Detection and Genotyping of Borrelia burgdorferi from Whole Blood of Patients with Early Lyme Disease. (2012) PLoS ONE 7(5): e36825. doi:10.1371/journal.pone.0036825 PMC3348129 Aucott JN, Crowder LA, Yedlin V, Kortte KB. Bull's-Eye and Nontarget Skin Lesions of Lyme Disease: An Internet Survey of Identification of Erythema Migrans. Dermatol Res Pract. V 2012. P 1-6. doi: 10.1155/2012/451727. Aucott JN, Seifter A, Rebman A. Probable late Lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection. BMC Infectious Diseases 2012;12 (1) 173 Aucott JN, Crowder L, Kortte KB. Development of a Foundation for a case definition of Post- treatment Lyme disease Syndrome. International Journal of Infectious Diseases. 2013; 17 (6) e443 - e449. Schutzer SE, Berger BW, Krueger J, Eshoo MW, Ecker DJ, and Aucott JN. Atypical Erythema Migrans in Patients with PCR-Positive Lyme Disease. Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 19, No. 5, May 2013 Soloski, M. J., Crowder, L. A., Lahey, L. J., Wagner, C. A., Robinson, W. H., Aucott, J. N. (2014) Serum Inflammatory Mediators as Markers of Human Lyme Disease Activity. PLOSOne- in press