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个人简介

He received his BSc from the University of East Anglia (1986), PhD from the University of Victoria (1991), and was a Postdoctoral Research Fellow in Japan with Seiji Shinkai (1991-95). He was awarded a Royal Society University Research Fellowship at the University of Birmingham (1995-2000) before moving to the University of Bath in 2001. Education/Academic qualification Doctor of Science, Structure-Activity Studies of Ion Channel Mimics, University of Victoria Award Date: 1 Jan 1991 Bachelor of Science, University of East Anglia Award Date: 1 Jan 1986 External positions Visiting Professor, Engineering Research Centre for Hainan Bio-Smart Materials and Bio-Smart Devices Mar 2023 Guest Professor, Henan Normal University Dec 2020 Adjunct Professor, Ewha Womans University Jan 2020 Guest Professor, Shanghai Normal University Dec 2019 Guest Professor, Beijing University of Chemical Technology May 2019 Guest Ptofessor, Qufu Normal University, Qufu Normal Uviversity Mar 2019 Visiting Professor, Sophia University Apr 2018 → Jul 2018 Guest Professor, Zhejiang University, Zhejiang University 2018 Guest Professor, Changzhou University 2017 Guest Professor, Shaanxi University of Science and Technology 2016 AMADEus Invited Professor, University of Bordeaux May 2015 → Jun 2015 Concurrent Professor, Nanjing University 2013 Guest Professor, Shandong Normal University 2011 Hai-Tian Scholar, Dalian University of Technology 2010 Guest Professor, East China University of Science and Technology 2010 Guest Professor, Xiamen University 2010 Visiting Professor (JSPS), Kyushu University Jan 2008 → Mar 2008 Visiting Professor (21st Century COE Program: Creation of Integrated Eco Chemistry), Osaka University Jul 2005 Visiting Professor, University of Tsukuba Jan 2005 → Feb 2005 Dec 2020 → … Adjunct Professor, Ewha Womans University Jan 2020 → … Guest Professor, Shanghai Normal University Dec 2019 → … Guest Professor, Beijing University of Chemical Technology May 2019 → … Guest Ptofessor, Qufu Normal University, Qufu Normal Uviversity Mar 2019 → … Visiting Professor, Sophia University Apr 2018 → Jul 2018 Guest Professor, Zhejiang University, Zhejiang University 2018 → … Guest Professor, Changzhou University 2017 → … Guest Professor, Shaanxi University of Science and Technology 2016 → … AMADEus Invited Professor, University of Bordeaux May 2015 → Jun 2015 Concurrent Professor, Nanjing University 2013 → … Guest Professor, Shandong Normal University 2011 → … Hai-Tian Scholar, Dalian University of Technology 2010 → … Guest Professor, East China University of Science and Technology 2010 → … Guest Professor, Xiamen University 2010 → … Visiting Professor (JSPS), Kyushu University Jan 2008 → Mar 2008 Visiting Professor (21st Century COE Program: Creation of Integrated Eco Chemistry), Osaka University Jul 2005 Visiting Professor, University of Tsukuba Jan 2005 → Feb 2005

研究领域

molecular recognition fluorescent sensor design fluorescence imaging theranostic systems chiral recognition saccharide recognition anion recognition sensors for reactive oxygen species (ROS) probes for redox imbalance

近期论文

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A BODIPY-based probe for amyloid-β imaging in vivo Zhu, M., Zhang, G., Hu, Z., Zhu, C., Chen, Y., James, T. D., Ma, L. & Wang, Z., 10 Mar 2023, In: Organic Chemistry Frontiers. 10, 8, p. 1903-1909 7 p. Aggregation-Induced Emission (AIE), Life and Health Wang, H., Li, Q., Alam, P., Bai, H., Bhalla, V., Bryce, M. R., Cao, M., Chen, C., Chen, S., Chen, X., Chen, Y., Chen, Z., Dang, D., Ding, D., Ding, S., Duo, Y., Gao, M., He, W., He, X., Hong, X., & 69 others, 8 Aug 2023, In: ACS Nano. 17, 15, p. 14347-14405 59 p. A hemicyanine-based fluorescent probe for ratiometric detection of ClO- and turn-on detection of viscosity and its imaging application in mitochondria of living cells and zebrafish James, T., 15 May 2023, In: Sensors and Actuators B: Chemical. 383, 133510. A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species Yan, K. C., Gardiner, J. E., Sedgwick, A. C., Thet, N., Heylen, R. A., James, T. D., Jenkins, A. T. A. & He, X. P., 7 Jul 2023, In: Chemical Communications. 59, 53, p. 8278-8281 4 p. Constructing A Solar Evaporator by Stacking Exhausted Wood Sponges for Freshwater Generation and Fertilizer Recovery Li, M., Xu, M., Wang, H., Liu, S., Xiao, Y., Wang, L. & James, T. D., 21 Jul 2023, (E-pub ahead of print) In: ChemSusChem. e202300426. Current trends in the detection and removal of heavy metal ions using functional materials Li, M., Shi, Q., Song, N., Xiao, Y., Wang, L., Chen, Z. & James, T., 2 Aug 2023, (E-pub ahead of print) In: Chemical Society Reviews. 34 p. Development of a hydroxyflavone-labelled 4554W peptide probe for monitoring αS aggregation Watt, K., Meade, R., James, T. & Mason, J., 31 Dec 2023, In: Scientific Reports. 13, 1, 10968. Fluorometric detection of volatile amines using an indanonalkene platform Zhang, P., Wu, T., Cao, H., Zhang, J., James, T. D. & Sun, X., 10 Jan 2023, (E-pub ahead of print) In: Organic Chemistry Frontiers. 10, 6, p. 1393-1398 6 p. Harnessing solar energy for electrocatalytic biorefinery using lignin-derived photothermal materials Zhao, X., Shi, L., Tian, B., Li, S., Liu, S., Li, J., Liu, S., James, T. D. & Chen, Z., 31 May 2023, In: Journal of Materials Chemistry A. 11, 23, p. 12308-12314 7 p. Human serum albumin-based supramolecular host-guest boronate probe for enhanced peroxynitrite sensing Tian, H., Guo, C., Hu, X. L., Wang, J. B., Zang, Y., James, T. D., Li, J. & He, X. P., 14 Jun 2023, In: Organic and Biomolecular Chemistry. 21, 22, p. 4661-4666 6 p. Article has an altmetric score of 1 Luminescent materials derived from biomass resources Ge, M., Liu, S., Li, J., Li, M., Li, S., James, T. D. & Chen, Z., 15 Feb 2023, In: Coordination Chemistry Reviews. 477, 214951. Metal–organic framework (MOF) hybridized gold nanoparticles as a bifunctional nanozyme for glucose sensing Tong, P. H., Wang, J-J., Hu, X. L., James, T. & He, X-P., 22 Jun 2023, (E-pub ahead of print) In: Chemical Science. 14, 28, 8 p. Multifunctional 1,3-benzoxazole-merocyanine-based probe for the ratiometric fluorescence detection of pH/HSO3−/viscosity in mitochondria Wu, W. N., Song, Y. F., Zhao, X. L., Wang, Y., Fan, Y. C., Xu, Z. H. & James, T. D., 15 May 2023, In: Chemical Engineering Journal. 464, 142553. Photoactivatable senolysis with single-cell resolution delays aging Shi, D., Liu, W., Gao, Y., Li, X., Huang, Y., Li, X., James, T., Guo, Y. & Li, J., 2 Feb 2023, (E-pub ahead of print) In: Nature Aging. Photoinduced electron transfer (PeT) based fluorescent probes for cellular imaging and disease therapy Niu, H., Liu, J., O'Connor, H. M., Gunnlaugsson, T., James, T. D. & Zhang, H., 7 Apr 2023, In: Chemical Society Reviews. 52, 7, p. 2322-2357 36 p. Polymer Indicator Displacement Assay (PIDA) with Boronic Acid Receptors on Graphene Foam Electrodes for Self-Optimised Impedimetric Lactic Acid Determination Wikeley, S. M., Lozano-Sanchez, P., Caffio, M., James, T. D. & Marken, F., 15 Feb 2023, In: Sensors and Actuators B: Chemical. 377, 133089. Ratiometric sensing of β-galactosidase based on excited-state intramolecular proton transfer (ESIPT) and solid-state luminescence enhancement Tian, H., Lin, W., Hu, X. L., Wang, J. B., Zhang, M. Y., Zang, Y., Wu, X. Y., Li, J., James, T. D. & He, X. P., 21 Jun 2023, In: Organic Chemistry Frontiers. 10, 12, p. 2913-2917 5 p. Recent advances in fluorescent and colorimetric chemosensors for the detection of chemical warfare agents: a legacy of the 21st century Kumar, V., Kim, H., Pandey, B., James, T. D., Yoon, J. & Anslyn, E. V., 21 Jan 2023, In: Chemical Society Reviews. 52, 2, p. 663-704 Recent progress in the development of fluorescent probes for imaging pathological oxidative stress Geng, Y., Wang, Z., Zhou, J., Zhu, M., Liu, J. & James, T. D., 16 May 2023, In: Chemical Society Reviews. 52, 11, p. 3873–3926 54 p. Responsive Probes and Molecular Bioimaging Zhang, R. & James, T. D., 1 Mar 2023, In: Chemistry - An Asian Journal. 18, 5, e202300058. Reversible Recognition-Based Boronic Acid Probes for Glucose Detection in Live Cells and Zebrafish Wang, K., Zhang, R., Zhao, X., Ma, Y., Ren, L., Ren, Y., Chen, G., Ye, D., Wu, J., Hu, X., Guo, Y., Xi, R., Meng, M., Yao, Q., Li, P., Chen, Q. & James, T. D., 16 Apr 2023, In: Journal of the American Chemical Society. 145, 15, p. 8408-8416 Room temperature phosphorescence from natural wood activated by external chloride anion treatment Zhai, Y., Li, S., Li, J., Liu, S., James, T. D., Sessler, J. L. & Chen, Z., 5 May 2023, In: Nature Communications. 14, 1, 2614. Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore Wu, Y., Han, H. H., He, L., Li, L., Zang, Y., Li, J., He, X. P., Ding, Y., Cao, W. & James, T. D., 6 Apr 2023, In: Chemical Communications. 59, 34, p. 5051-5054 4 p. Self-Assembled Artificial Light-Harvesting System Constructed Using Electrostatic Interactions in Aqueous Solution for the Sensing of Heavy Metal Cations Li, M., Shi, Q., Song, N., Chen, Z., Wang, L. & James, T. D., 30 May 2023, (E-pub ahead of print) In: Advanced Optical Materials. 9 p., 2203079. Structure-activity of chlormethine fluorescent prodrugs: Witnessing the development of trackable drug delivery Jin, W., Fan, B., Qin, X., Liu, Y., Qian, C., Tang, B., James, T. D. & Chen, G., 30 Apr 2023, In: Coordination Chemistry Reviews. 480, p. 214999 Targeted photothermal release of antibiotics by a graphene nanoribbon-based supramolecular glycomaterial Shang, Y., Zhang, S., Gan, H-Q., Yan, K-C., Xu, F., Mai, Y., Chen, D., Hu, X., Zou, L., James, T. D. & He, X-P., 25 Jan 2023, In: Chemical Communications. 59, 8, p. 1094-1097 The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy Han, H. H., Wang, H. M., Jangili, P., Li, M., Wu, L., Zang, Y., Sedgwick, A. C., Li, J., He, X. P., James, T. D. & Kim, J. S., 13 Jan 2023, In: Chemical Society Reviews. 52, 3, p. 879-920 42 p. Tumor microenvironment-oriented MOFs for chemodynamic therapy Di, X., Pei, Z., Pei, Y. & James, T. D., 1 Jun 2023, In: Coordination Chemistry Reviews. 484, 215098. Visualizing Drug Release from a Stimuli-Responsive Soft Material Based on Amine-Thiol Displacement Wu, T., Huang, S., Feng, X., Liu, X., James, T. D., Sun, X. & Qian, X., 17 May 2023, In: ACS Applied Materials and Interfaces. 15, 19, p. 22967-22976 “All-in-one” carbon dots-based catalyst for converting CO2 to cyclic carbonates Wang, R., Wan, J., Guo, H., Tian, B., Li, S., Li, J., Liu, S., James, T. D. & Chen, Z., 25 Jun 2023, In: Carbon. 211, 9 p., 118118. A molecular recognition platform for the simultaneous sensing of diverse chemical weapons Zeng, L., Chen, T., Zhu, B., Koo, S., Tang, Y., Lin, W., James, T. D. & Kim, J. S., 28 Apr 2022, In: Chemical Science. 13, 16, p. 4523-4532 An endoplasmic reticulum targeting green fluorescent protein chromophore-based probe for the detection of viscosity Wei, X., Zhu, Y., Yu, X., Cai, L., Ruan, N., Wu, L., Jia, N., James, T. D. & Huang, C., 28 Sept 2022, In: Chemical Communications. 58, 76, p. 10727-10730 An upcycled wood sponge adsorbent for drinking water purification by solar steam generation Li, M., Xu, M., Shi, Q., Wang, H., Guo, H., Wang, L. & James, T. D., 1 Jul 2022, In: Environmental Science: Nano. 9, 7, p. 2559-2571 13 p. A photosensitive sustainable lignin nanoplatform for multimodal image-guided mitochondria-targeted photodynamic and photothermal therapy Liu, X., Li, M., Li, X., Ge, M., Liu, S., Li, S., Li, J., Ding, J., Ragauskas, A. J., Sun, W., James, T. D. & Chen, Z., 31 Dec 2022, In: Materials Today Chemistry. 26, 101000. A practical strategy to develop isoform-selective near-infrared fluorescent probes for human cytochrome P450 enzymes Feng, L., Tian, X., Yao, D., Yu, Z., Huo, X., Tian, Z., Ning, J., Cui, J., James, T. D. & Ma, X., 30 Apr 2022, In: Acta Pharmaceutica Sinica B. 12, 4, p. 1976-1986 11 p. A spiropyran with low pKa for tracking DNA G-quadruplexes and revealing the dissipation of ΔΨm with senescence using an in-situ switching strategy Tian, X., Li, J., Zhang, Y., Gao, Y., Afzal, M. W., Wang, A., James, T. D., Bai, Y. & Guo, Y., 15 May 2022, In: Sensors and Actuators B: Chemical. 359, 131618. Dual-Channel Fluorescent Probe for the Simultaneous Monitoring of Peroxynitrite and Adenosine-5′-triphosphate in Cellular Applications Wu, L., Liu, J., Tian, X., Groleau, R. R., Feng, B., Yang, Y., Sedgwick, A. C., Han, H. H., Wang, Y., Wang, H. M., Huang, F., Bull, S. D., Zhang, H., Huang, C., Zang, Y., Li, J., He, X. P., Li, P., Tang, B., James, T. D., & 1 others, 12 Jan 2022, In: Journal of the American Chemical Society. 144, 1, p. 174-183 10 p. Editorial: Suprastars of Chemistry Xiao, T., James, T. D., Borovkov, V., Castellano, R. K. & Deng, C., 6 Jun 2022, In: Frontiers in Chemistry. 10, 932508. Exhausted Cr(VI) Sensing/Removal Aerogels Are Recycled for Water Purification and Solar-Thermal Energy Generation Li, X., Li, M., Shi, Q., Guo, H., Wang, L., Guo, X., Chen, Z., Sessler, J. L., Xiao, H. & James, T. D., 1 Sept 2022, In: Small. 18, 35, 2201949. Fluorescent probes and functional materials for biomedical applications Hu, X. L., Gan, H. Q., Meng, F-D., Han, H. H., Shi, D-T., Zhang, S., Zou, L., He, X-P. & James, T., 31 Oct 2022, In: Frontiers of Chemical Science and Engineering. 16, 10, p. 1425-1437 13 p. Fluorescent probes for the detection of disease-associated biomarkers Dou, W. T., Han, H. H., Sedgwick, A. C., Zhu, G. B., Zang, Y., Yang, X. R., Yoon, J., James, T. D., Li, J. & He, X. P., 30 Apr 2022, In: Science Bulletin. 67, 8, p. 853-878 26 p. High-throughput fluorescent screening of β -lactamase inhibitors to improve antibiotic treatment strategies for tuberculosis Yan, F., He, S., Han, X., Wang, J., Tian, X., Wang, C., James, T., Cui, J., Ma, X. & Feng, L., 15 Nov 2022, In: Biosensors and Bioelectronics. 216, 114606. Imaging of hypochlorous acid in mitochondria using an asymmetric near-infrared fluorescent probe with large Stokes shift Hu, W., Qiang, T., Li, C., Ren, L., Chang, F., Wang, B., Li, M., Song, X. & James, T., 14 Oct 2022, In: Chemical Science. 13, p. 11140-11149 Metabolically Specific In Situ Fluorescent Visualization of Bacterial Infection on Wound Tissues Zhong, C. J., Hu, X. L., Yang, X. L., Gan, H. Q., Yan, K. C., Shu, F. T., Wei, P., Gong, T., Luo, P. F., James, T. D., Chen, Z. H., Zheng, Y. J., He, X. P. & Xia, Z. F., 7 Sept 2022, In: ACS Applied Materials and Interfaces. 14, 35, p. 39808-39818 11 p. MOF-Derived Robust and Synergetic Acid Sites Inducing C-N Bond Disruption for Energy-Efficient CO2Desorption Xing, L., Li, M., Li, M., Xu, T., Li, Y., Qi, T., Li, H., Hu, Z., Hao, G. P., Zhang, S., James, T. D., Mao, B. & Wang, L., 20 Dec 2022, In: Environmental Science and Technology. 56, 24, p. 17936-17945 10 p. Molecularly engineered AIEgens with enhanced quantum and singlet-oxygen yield for mitochondria-targeted imaging and photodynamic therapy Xu, F. Z., Zhu, L., Han, H. H., Zou, J. W., Zang, Y., Li, J., James, T. D., He, X. P. & Wang, C. Y., 28 Aug 2022, In: Chemical Science. 13, 32, p. 9373-9380 mtDNA-Specific Ultrasensitive Near-Infrared Fluorescent Probe Enables the Differentiation of Healthy and Apoptotic Cells Wang, Y., Niu, H., Wang, K., Wang, G., Liu, J., James, T. D. & Zhang, H., 31 May 2022, In: Analytical Chemistry. 94, 21, p. 7510-7519 10 p. Nanococktail Based on Supramolecular Glyco-Assembly for Eradicating Tumors In Vivo Feng, W., Zhang, S., Wan, Y., Chen, Z., Qu, Y., Li, J., James, T. D., Pei, Z. & Pei, Y., 11 May 2022, In: ACS Applied Materials and Interfaces. 14, 18, p. 20749-20761 13 p. Nanoplatforms with synergistic redox cycles and rich defects for activatable image-guided tumor-specific therapy Zhu, H., Yin, X., Zhou, Y., Xu, S., James, T. D. & Wang, L., 8 Sept 2022, In: Chem. 8, 9, p. 2498-2513 16 p. Near-infrared fluorescent probe for hydrogen sulfide: High-fidelity ferroptosis evaluation in vivo during stroke Liang, T., Qiang, T., Ren, L., Cheng, F., Wang, B., Li, M., Hu, W. & James, T. D., 28 Apr 2022, In: Chemical Science. 13, 10, p. 2992-3001 10 p.

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