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个人简介

教育经历 03.2015–09.2018, Postdoc fellow/project leader, Depart. of Chemistry, 德州大学奥斯汀分校, USA, Collaborators: Prof. Eric V. Anslyn, Prof. Andrew Ellington; 09.2012–02. 2015, PhD, Depart. of Chemistry, 巴斯大学, UK, Supervisors: Prof. Tony D. James, Prof. Steven Bull; 03.2012–09. 2012, R&D researcher, Shanghai, 东京化成上海化学品公司(TCI); 09.2009–03.2012, MSc, Applied Chemistry, School of Phamacy, 华东理工大学, Supervisor:Xuhong Qian (Member of Chinese Academy of Engineering); 09.2005–06.2009, BSc, Department of Resources and Environment, 陕西科技大学 学术成绩简介 近五年来,孙晓龙博士参与多项美国国防威胁署、国防高等研究计划署以及美国自然科学基金的项目,重要成果体现在以第一作者身份发表科研论文16篇,包括Chem. Rev. (IF: 54.301)1篇(ESI高被引)、Nat. Chem. (IF: 23.193)1篇、JACS (IF: 14.695)2篇、Angew. Chem. Int. Ed.(IF: 12.257)1篇、ACS Cent. Sci. (IF:12.837)1篇、Chem. Sci. (IF:9.556)3篇。发表于ACS Central Science的研究成果,被《泰晤士报》The Times、福克斯新闻 Fox News、美国科学促进会EurekAlert、人民网、参考消息等100多家国内外新闻媒体以通讯稿/视频采访的形式予以报道。一作揭示葡萄糖荧光识别机理的研究成果(Journal of the American Chemical Society 2018, 140, 2348),被美国化学会志选为热点以DEMYSTIFYING THE FLUORESCENCE OF BORONIC ACID-BASED SUGAR SENSORS 为题在Spotlights on Recent JACS Publications上报道。国内外知名学者、知名杂志主编、副主编等对其在荧光传感识别领域的诸多成绩给予引用报道。另外,团队申请国际发明专利一项(PCT:WO 2015128622);中国发明专利一项(CN 102806070)。 另外,在2016年分子传感与逻辑门(MSMLG)国际会议做邀请报告、2019年环境催化与传感国际会议(CASE)上做邀请报告;参加国际会议6次,获得2016 MSMLG 会议最佳墙报奖、2013年英日双边J400 Chemonostics会议最佳墙报奖。此外,还曾担任JACS、RSC Advances、Dyes and Pigments、Textile Research Journal、ChemistrySelect、《精细化工》等国际期刊审稿人。

研究领域

荧光传感技术及生物/环境应用,功能材料开发 (1) 光学信号级联放大体系的构建 (2) 新型荧光探针和光学标记染料的开发 (3) 色度光谱分析技术平台的开发 (4) 功能/智能高分子材料开发及应用、便携设备的制造

近期论文

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Sun X., Chwatko M., Lee D. H., Batchman J. L., Reuther J. F., Lynd N. A.,* Anslyn E. V.* Chemically-triggered synthesis, remodelling, and degradation of soft materials. 2019, In Preparation; Sun X., Liang T., Edupuganti R., Qiang T, James T. D.,* Anslyn E. V.* Investigation of binding affinities between boronic acid and saccharide-mimicked diols via indicator displacement assay. Front. Chem. 2019, In Preparation; Wu, L.; Sedgwick, A. C.; Sun, X.; Bull, S. D.; He, X.; James, T. D., Reaction-based fluorescent probes for the detection and imaging of reactive oxygen, nitrogen and sulfur species. Acc. Chem. Res. 2019, Accept (IF: 21.661) Meadows M. K.,‡ Sun X.‡ Kolesnichenko I. V., Hinson C., Johnson K. A.,* Anslyn E. V.* Mechanistic Studies of a “Declick” Reaction. Chem. Sci. 2019, DOI: 10.1039/C9SC00690G (IF: 9.556). Wu, L.; Sedgwick, A. C.; Sun, X.; Bull, S. D.; He, X.; James, T. D., Reaction-based fluorescent probes for the detection and imaging of reactive oxygen, nitrogen and sulfur species. Acc. Chem. Res. 2019, Accept (IF: 21.661) Sun X., Chapin B. M., Metola P., Collins B., Wang B.,* James T. D.,* Anslyn E. V.* The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids. Nat. Chem. 2019, 11, 768-778 (IF: 23.193). Sun X.,† Boulgakov A. A.,† Smith L. N., Metola P., Marcotte E. M.,* Anslyn E. V.* Photography Coupled with Self-Propagating Chemical Cascades: Differentiation and Quantitation of G and V Nerve Agent Mimics via Chromaticity. ACS. Cent. Sci. 2018, 4, 854-861 (IF: 12.837) Sun X., James T. D.,* Anslyn E. V.* Arresting “Loose Bolt” Internal Conversion from −B(OH)2 Groups is the Mechanism for Emission Turn-On in ortho-Aminomethylphenylboronic Acid-Based Saccharide Sensors. J. Am. Chem. Soc. 2018, 140, 2348–2354 (IF: 14.695) Sun X., Anslyn E. V.* An Auto-Inductive Cascade for the Optical Sensing of Thiols in Aqueous Condition: Application in the Detection of a VX Nerve Agent Mimic. Angew. Chem. Int. Ed. 2017, 129, 9650-9654 (IF: 12.257); Sun X., Dahlhauser S. D. Anslyn E. V.* New Auto-Inductive Cascade for the Optical Sensing of Fluoride: Application in the Detection of Phosphoryl Fluoride Nerve Agents. J. Am. Chem. Soc. 2017, 139, 4635-4638 (IF: 14.695); Sun, X., James, T. D.* Glucose Sensing in Supramolecular Chemistry. Chem. Rev. 2015, 115, 8001-8037 (IF: 54.301); Guo, S.; Chen, J.; Cai, B.-Y.; Chen, W.-W.; Li, Y.-F.; Sun, X.; Chen, G.-R.; He, X.-P.; James, T. D., Low-dimensional materials facilitate the conjugation between fluorogenic boronic acids and saccharides. Materials Chemistry Frontiers 2017, 1 (1), 61-64. Sun X., Lacina K., Ramsamy E., Flower S. E., Fossey J. S., Qian X. H., Anslyn E. V.,* Bull S.,* and James T. D.* Reaction-based Indicator displacement Assay (RIA) for the selective colorimetric and fluorometric detection of peroxynitrite. Chem. Sci. 2015, 6, 2963-2967 (IF: 9.556); Sun, X., Xu, Q.; Kim, G., Flower, S. E., Lowe, J. P., Yoon, J., Fossey, J. S., Qian, X. H., Bull, S.,* and James, T. D.* A water-soluble boronate-based fluorescence probe for the selective detection of peroxynitrite and imaging in living cells. Chem. Sci. 2014. 5, 3368-3373 (Front cover, IF: 9.556); Lampard, E. V.; Sedgwick, A. C.; Sun, X.; Filer, K. L.; Hewins, S. C.; Kim, G.; Yoon, J.; Bull, S. D.; James, T. D., Boronate‐Based Fluorescence Probes for the Detection of Hydrogen Peroxide. ChemistryOpen 2018, 7 (3), 262-265. Yevglevskis, M.; Lee, G. L.; Sun, J.; Zhou, S.; Sun, X.; Kociok-Köhn, G.; James, T. D.; Woodman, T. J.; Lloyd, M. D., A study on the AMACR catalysed elimination reaction and its application to inhibitor testing. Org. Bio. Chem. 2016, 14 (2), 612-622. Sun, X.,† Zhu, B.,† Ji, D.-K., Chen, Q., He, X.-P.,* Chen, G. R.,* James, T. D.,* Selective Fluorescence Detection of Monosaccharides Using a Material Composite Formed Between Graphene Oxide and Boronate-based Receptors. ACS Appl. Mater. Interfaces. 2014, 6, 10078–10082 (IF: 8.456); Sun, X., S.-Y. Xu, S. E. Flower, J. S. Fossey, X. Qian and T. D. James.* "Integrated" and "insulated" boronate-based fluorescent probes for the detection of hydrogen peroxide. Chem. Commun. 2013, 49, 8311-8313 (Front cover, reported in various scientific media, IF: 6.164); Sedgwick, A. C.; Sun, X.; Kim, G.; Yoon, J.; Bull, S. D.; James, T. D., Boronate based fluorescence (ESIPT) probe for peroxynitrite. Chem. Commun. 2016, 52 (83), 12350-12352. Sun X., Zhai W., Fossey J. S. and James T. D.* Boronic acid for fluorescence imaging of carbohydrate. Chem. Commun. feature article. 2016, 52, 3456-3469 (Front cover, IF: 6.164); Sun X., Reuther J. F., Phillips S. T.,* Anslyn E. V.* Coupling Activity-based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents. Chem. Eur. J. 2017, 23, 3903-3909 (IF: 5.160);

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