车会莲 - 中国农业大学 - 食品科学与营养工程学院

个人简介

2005年以来一直致力于食物营养、食品过敏、食品安全性评价等领域的研究，尤其是在食物致敏原的鉴定、致敏性评估、过敏机理及抗过敏功能等研究方面，取得了一批具有领先水平的研究成果；同时，在保健食品、婴幼儿配方食品和特殊医学用途配方食品的研发、评价、咨询等方面也开展了很多工作。十余年来，主持各类国家级、省部级科研项目10余项、申请专利21件、7项已经获得了授权，2项实现了转化，获得软件著作权10件、参与制定国家标准5个，在国内外学术刊物上发表论文百余篇。教育经历 1995.9 - 2000.7，哈尔滨医科大学，预防医学，学士学位 2000.9 - 2005.7，哈尔滨医科大学，营养与食品卫生学，博士学位工作经历 2005.7 – 至今，中国农业大学食品科学与营养工程学院教授课程食品毒理学、食品营养学、食品免疫学、基础营养学等

研究领域

食品营养与安全、食物过敏、特殊食品

近期论文

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Wang J.J, Guo X.Y, Chen C, Sun S.F, Liu G.R, Liu M.M, Hao M.Z, Che H.L*. Gender differences in food allergy depend on the PPAR γ/NF-κB in the intestines of mice, Life Sciences,2021. Chen C, Yin Q.Y, Wu H, Cheng L, Kwon J.I, Jin J, Han T.Y, Che H.L*. Different Effects of Premature Infant Formula and Breast Milk on Intestinal Microecological Development in Premature Infants[J]. Frontiers in Microbiology,2020. Yang S, Chew H.F, Jiang Y.C, Cheng L, Guo X.Y, Che H.L & Sun N*. Lentinan Inhibited the Activation of Th2 Cells in Allergic Mice by Reducing the Amplitude of Changes in Biological Rhythm[J]. International archives of allergy and immunology, 2020. Guo X.Y, Jiang S.S, Li X.R, Yang S, Cheng L, Qiu J.Y, Che H.L*. Sequence analysis of digestion-resistant peptides may be an efficient strategy for studying the linear epitopes of Jug r 1, the major walnut allergen[J]. Food Chemistry,2020. Zhang E.K, Zhang Y.N, Fan Z.Y, Cheng L, Han S.W, Che H.L*. Apigenin Inhibits Histamine-Induced Cervical Cancer Tumor Growth by Regulating Estrogen Receptor Expression. Molecules. 2020. Wang L.Y, Wang X.Y, Chen A.X, Jin X, Che H.L*. Prediction of Type 2 Diabetes Risk and Its Effect Evaluation Based on the XGBoost Model. Healthcare (Basel),2020. Yao L, Fan Z.Y, Han S.W, Sun N, Che H.L*. Apigenin Attenuates the Allergic Reactions by Competitively Binding to ER With Estradiol. Front Pharmacol,2020. Sun S.F, Jiang S.S, Wang J.J, Chen C, Han S.W, Che H.L*. Cholera toxin induces food allergy through Th2 cell differentiation which is unaffected by Jagged2. Life Sci,2020. Fan Z.Y, Che H.L*, Yang S, Chen C. Estrogen and estrogen receptor signaling promotes allergic immune responses: Effects on immune cells, cytokines, and inflammatory factors involved in allergy. Allergologia et Immunopathologia, 2019. Jiang T.Y, He F, Han S.W, Chen C, Zhang Y.N, Che H.L*. Characterization of cAMP as an anti-allergic functional factor in Chinese jujube (Ziziphus jujuba Mill). Journal of Functional Foods,2019. Che H.L, Zhang Y.Z，Jiang S.S，Jin T.C，Lyu Shu-Chen，Kari C.N，Tara M.H. Almond (Prunus dulcis) allergen Pru du 8, the first member of a new family of food allergens. Journal of agricultural and food chemistry, 2019. Che H.L, Zhang Y.Z, Shu-Chen Lyu, Kari C. N, Tara M.H. Identification of Almond (Prunus dulcis) Vicilin As a Food Allergen, Journal of Agricultural and Food Chemistry, 2019. Lianto P, Ogutu F.O, Zhang Y.N, He F, Che H.L*. Inhibitory effects of quail egg on mast cells degranulation by suppressing PAR2-mediated MAPK and NF-kB activation. Food & nutrition research,2018. Jiang S.S, Da Y.F, Han S.W, He Y.H, Che H.L*. Notch ligand Delta-like1 enhances degranulation and cytokine production through a novel Notch/Dok-1/MAPKs pathway in vitro.[J]. Immunologic research,2018. Han S.W, Sun L, He F, Che H.L*. Anti-allergic activity of glycyrrhizic acid on IgE-mediated allergic reaction by regulation of allergy-related immune cells[J]. Scientific Reports, 2017. Zhou C, Ludmila T, Sun N, Wang C.Y, Pu Q.K, Huang K.L, Che H.L*. BALB/c mice can be used to evaluate allergenicity of different food protein extracts[J]. Food and Agricultural Immunology, 2016. 主编专著现代食品安全学，科学出版社，2018.1。食品安全实验，中国林业出版社，2018.1。食品免疫学，中国农业大学出版社，2017.06。食品卫生与安全，科学出版社，2017.1。食品安全性评价综合实验，中国林业出版社，2014.10。最佳食物搭配方案，江西科学技术出版社，2007.02。家庭饮食健康方案，江西科学技术出版社，2007.02。