个人简介
2022.1-至今：中国农业大学营养与健康系教授
2019.6-2020.6: 美国加州大学戴维斯分校做访问学者
2017.1-2021.12：中国农业大学食品科学与营养工程学院教授
2012.6-2013.6：荷兰瓦赫宁根大学做访问学者
2007.1-2016.12：中国农业大学食品科学与营养工程学院副教授
2004.7-2006.12：中国农业大学食品科学与营养工程学院讲师
2001.9-2004.7：中国农业大学，食品科学专业，获博士学位
1998.9-2001.2：哈尔滨商业大学，食品科学专业，获硕士学位
1993.5-1997.7：东北农业大学，食品科学与工程专业，获学士学位
研究领域
益生菌肠道适应机制的研究
乳酸菌次级代谢产物的结构及生物合成机制研究
乳酸菌发酵剂及微生态制剂的开发
近期论文
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Zhengyuan Zhai, Shuxins Xie, Hongxing Zhang, Huaxi Yi and Yanling Hao*. Homologous over-expression of chain length determination protein EpsC increases the molecular weight of exopolysaccharide in streptococcus thermophilus 05-34. Frontiers in Microbiology, 2021, 12:696222.
Yao Xiong, Zhengyuan Zhai, Yuanqiu Lei, Bingbing Xiao, and Yanling Hao*. A Novel Major Pilin Subunit Protein FimM Is Involved in Adhesion of Bifidobacterium longum BBMN68 to Intestinal Epithelial Cells. Frontiers in Microbiology, 2020, 11:590435.
Zhengyuan Zhai, Yang Yang, Hui Wang, Guohong Wang, Fazheng Ren, Zaigui Li, Yanling Hao*. Global transcriptomic analysis of Lactobacillus plantarum CAUH2 in response to hydrogen peroxide stress. Food Microbiology, 2020, 87:103389.
Guohong Wang, Jiaxi Li, Shuxin Xie, Zhengyuan Zhai, and Yanling Hao*.The N-terminal domain of rhamnosyltransferase EpsF influences exopolysaccharide chain length determination in Streptococcus thermophilus 05-34. Peer J, 2020, 8:e8524.
Guohong Wang, Zhengyuan Zhai, Fazheng Ren, Zaigui Li, Bing Zhang and Yanling Hao*.Combined transcriptomic and proteomic analysis of the response to bile stress in a centenarian-originated probiotic Lactobacillus salivarius Ren. Food Research International, 2020, 137:109331.
Qi Xu, Zhengyuan Zhai, Haoran An, Yang Yang, Jia Yin, Guohong Wang, Fazheng Ren and Yanling Hao*. The MarR Family Regulator BmrR Is Involved in Bile Tolerance of Biodobacterium longum BBMN68 via Controling the Expression of an ABC Transporter. Appl. Environ. Microbiol., 2019, 85.3: e02453-18.
Xiayin Ma, Guohong Wang, Zhengyuan Zhai, Pengyu Zhou and Yanling Hao*. Global Transcriptomic Analysis and Function Identification of Malolactic Enzyme Pathway of Lactobacillus paracasei L9 in Response to Bile Stress. Frontiers in Microbiology, 2018, 9:1978-1989.
Pengyu Zhou, Zhengyuan Zhai, Yao Xiong, Peihua Ma and Yanling Hao*. Characterization of a Cryptic Rolling-Circle Replication Plasmid pMK8 from Enterococcus durans 1–8. Current Microbiology, 2018, 75:1198–1205.
Yang Yang, Jia Yin, Jie Liu, Qi Xu, Tian Lan, Fazheng Ren and Yanling Hao*. The Copper Homeostasis Transcription Factor CopR Is Involved in H2O2 Stress in Lactobacillus plantarum CAUH2. Frontiers in Microbiology, 2017, 8:2015-2025.
Dan Li, Jiaxi Li, Feng Zhao, Guohong Wang, Qianqian Qin and Yanling Hao*. The influence of fermentation condition on production and molecular mass of EPS produced by Streptococcus thermophilus 05-34 in milk-based medium. Food Chemistry. 2016, 367-372.
Wanli Zhou, Guohong Wang, Chunmei Wang, Fazheng Ren, Yanling Hao*. Both IIC and IID Components of Mannose Phosphotransferase System Are Involved in the Specific Recognition between Immunity Protein PedB and Bacteriocin-Receptor Complex. PLOS ONE, 2016, 11(10) :e0164973.
Haoran An, Fran?ois P. Douillard, Guohong Wang, Zhengyuan Zhai, Jin Yang, Shuhui Song, Jianyun Cui, Fazheng Ren, Yunbo Luo, Bing Zhang and Yanling Hao*. Integrated transcriptomic and proteomic analysis of the bile stress response in a centenarian-originated probiotic Bifidobacterium longum BBMN68. Molecular & Cellular Proteomics. 2014.13(10):2558-2572.
Zhao F, Wang Y, An H, Hao Y*, Hu X and Liao X*. New Insights into the Formation of Viable but Nonculturable Escherichia coli O157:H7 Induced by High-Pressure CO2.MBio, 2016 Aug 30;7 (4). pii: e00961-16. doi: 10.1128/mBio.00961-16.
Zhengyuan Zhai, Fran?ois P. Douillard, Haoran An, Guohong Wang, Xinghua Guo, Yunbo Luo and Yanling Hao*. Proteomic characterization of the acid tolerance response in Lactobacillus delbrueckii subsp. bulgaricus CAUH1 and functional identification of a novel acid stress-related transcriptional regulator Ldb0677. Environmental Microbiology. 2014, 16 (6), 1524–1537.
Zhengyuan Zhai, Haoran An, Guohong Wang, Yunbo Luo and Yanling Hao*. Functional role of pyruvate kinase from Lactobacillus bulgaricus in acid tolerance and identification of its transcription factor by bacterial one-hybrid. Scientific Reports. 2015, 19(5): 17024.doi:10.1038/srep 17024.
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