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个人简介

刘尚钟,1968年出生,1986年9月开始在原北京农业大学攻读本科学位,1993年在加入中国共产党,1996年获得中国农业大学理学博士学位,现为中国农业大学三级教授,博士生导师,理学院应用化学系系主任、兼任中国农药工业协会理事、中国植物保护协会理事。 主要从事新生物活性分子的创新研究、天然产物的全合成、生物活性化合物的工艺优化、酶联免疫与荧光偏振检测技术等,先后主持或参加了国家“十一五”、“十二五”科技支撑计划、国家自然科学基金、国家973项目等。目前,已在国内外学术期刊发表学术论文50余篇,申请国内外专利10项,国内授权专利3项、国际授权专利一项。

研究领域

主要从事新生物活性分子的创新研究、天然产物的全合成、生物活性化合物的工艺优化、酶联免疫与荧光偏振检测技术等

近期论文

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Hao Zhang, Rui-Quan Liu, Ke-Chang Liu, Qi-Bo Li, Qing-Yang Li and Shang-Zhong Liu,A One-Pot Approach to Pyridyl Isothiocyanates from Amines, Molecules 2014, 19, 13631-1364 欧俊军,刘克昌,王毅, 张浩,刘瑞全, 李奇博,汪清民,李永强, 芮昌辉, 刘尚钟*, 2,3-二取代喹唑啉-4(3H)-酮化合物的合成及生物活性研究, 有机化学,, 34,526-536 Cui, Yongliang; Liu, Kechang; Xu, Chuan; Liu, Feng; Li, Qing X.; Liu, Shangzhong; Wang, Baomin. Development of a sensitive monoclonal antibody-based indirect competitive enzyme-linked immunosorbent assay for analysing chlorantraniliprole residues. Food Chemistry, 2014, 143, 293-299. Guo, Lei; Wang, Yi; Zhou, Xuguo; Li, Zhenyu; Liu, Shangzhong; Pei, Liang; Gao, Xiwu. Functional analysis of a point mutation in the ryanodine receptor of Plutella xylostella (L.) associated with resistance to chlorantraniliprole. Pest Management Science, 2014, 70(7):1083-9. Chuan Xu, Junjun Ou, YongLiang Cui, Lei Wang, Cong Lv, Baoming Wang, Ting Xu, Qing X. Li, Shangzhong Liu, Development of a Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay for the analysis of Tetrabromobisphenol A, Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2013, 32, 113-118. Wang, Lei; Liu, Ruiquan; Lv, Cong; Ou, Junjun; Liu, Feng; Liu, Shangzhong; Wang, Min; Zhong, Jiangchun. Catalytic enantioselective synthesis of optically active a -hydroxyl-b ,g -unsaturated acid esters as novel side chains of cerebrosides. Tetrahedron: Asymmetry, 2013, 24(4), 173-177. Junjun Ou, Xiaokun Zhu, Lei Wang, Chuan Xu, Feng Liu, Long Ren, Xibao Xu, Yi Wang, Changhui Rui, and Shangzhong Liu, Synthesis and Bioactivity Study of 2?Acylamino-Substituted N?Benzylbenzohydrazide Derivatives, J. Agric. Food Chem. 2012, 60, 10942?10951. Yi Wang, Lei Guo, Suzhen Qi, Hao Zhang, Kechang Liu, Ruiquan Liu, Pei Liang, John E. Casida and Shangzhong Liu 1,* Fluorescent Probes for Insect Ryanodine Receptors: Candidate Anthranilic Diamides, Molecules, 2014, 19, 4105-4114. Ting Xu, Jia Wang, Shang-zhong Liu, Cong Lv, Weilin L. Shelver, Qing X. Li, Ji Li, A highly sensitive and selective immunoassay for the detection of tetrabromobisphenol A in soil and sediment, Analytica Chimica Acta 751 (2012) 119-127 Feng Liu, Yi Wang, Cong Lv, Lei Wang, Junjun Ou, Min Wang and Shangzhong Liu, Impact of Halogen Substituents on Interactions between 2-Phenyl-2,3-dihydro -qulinazolin-4(1H)-one Derivatives and Human Serum Albumin, Yongliang Cui, Tiegui Nan, Guiyu Tan, Qing X. Li, Baomin Wang, and Shangzhong Liu, Production of Monoclonal Antibody to Herbicide Fenoxaprop-ethyl, Hybridoma, 2011, 30(5), pp 463-467 Bing Zheng, Min Wang, Zhiyuan Li, Qinghua Bian, Jianyou Mao, Shuoning Li, Shangzhong Liu, Mingan Wang, Jiangchun Zhong, Hongchao Guo, Asymmetric Henry reaction catalyzed by a Zn-amino alcohol system, Tetrahedron: Asymmetry 22 (2011) 1156-1160. Zhi-Yuan Li, Min Wang, Qing-Hua Bian, Bing Zheng, Jian-You Mao, Shuo-Ning Li, Shang-Zhong Liu, Ming-An Wang, Jiang-Chun Zhong, and Hong-Chao Guo, Highly Enantioselective Addition of Trimethylsilylacetylene to Aldehydes Catalyzed by a Zinc-Amino-Alcohol Complex, Chemistry a European Journal, 2011, 17, 5782-5786. Ting Xu, Ke Yi Wei, Jia Wang , Sergei A. Eremin, Shang Zhong Liu, Qing X. Li, Ji Li, Development of an enzyme-linked immunosorbent assay specific to Sudan red I, Analytical Biochemistry 2010, 405, 41-49 Ming Liu, Yi Wang, Wei-Zi Wangyang, Feng Liu, Yong-Liang Cui, You-Sheng Duan, Min Wang, Shang-Zhong Liu,* and Chang-Hui Rui, Design, Synthesis, and Insecticidal Activities of Phthalamides Containing a Hydrazone Substructure, J. Agric. Food Chem. 2010, 58, 6858–6863 Ming Liu, Yongliang Cui, Yousheng Duan, Jiangchun Zhong, Wei Sun, Min Wang, Shangzhong Liu* and Qing X. Li, Synthesis of Metabolites of Polycyclic Aromatic Hydrocarbons, Mini-Reviews in Organic Chemistry, 2010, 7, 134-144 Jiang-Chun Zhong, Shi-Cong Hou, Qing-Hua Bian, Min-Min Yin, Ri-Song Na, Bing Zheng, Zhi-Yuan Li, Shang-Zhong Liu,* and Min Wang*, Highly Enantioselective Zinc/Amino Alcohol-Catalyzed Alkynylation of Aldehydes, Chemistry a European Journal, 2009, 15, 3069-3071. Yousheng Duan, Ming Liu, Wei Sun, Min Wang, Shangzhong Liu* and Qing X. Li. Recent Progress on Synthesis of Fluorescein Probes, Mini-Reviews in Organic Chemistry, 2009, 6, 35-43 Xu, Ting; Jing, Hongyu; Li, Qingxiao; Liu, Shangzhong; Sheng, Wei; Li, Ji. Development of an enzyme-linked immunosorbent assay for the detection of pentachlorophenol residues in water samples. Food and Agricultural Immunology 2007, 18(3-4), 189-201. Gao, Jinshan; Guo, Hongchao; Liu, Shangzhong; Wang, Min. Efficient soluble polymer-supported tartrate/Ti catalyst for asymmetric oxidation of prochiral sulfides. Tetrahedron Letters 2007, 48(48), 8453-8455. Liu Shangzhong, Li Qing-X. Design and Synthesis of Photoaffinity Probe Candidates for the GABA-gated Chloride Channel, Chinese Journal of Chemistry, 2006, 24, 1435-1438 Liu, S.-Z.; Li, Q.X. Photolysis of Spinosyns in seawater, stream water and various aqueous solutions. Chemosphere, 2004, 56, 1121-1127. Liu, S.-Z.; Li, Q.X. Photoaffinity Probe Candidates for Gamma-aminobutyric Acid (GABAA)-Gated Chloride Channel. Chinese Chemical Letters. 2004, 17(7), 773 Hong-Chao Guo, Xue-Yan Shi, Xian Wang, Shangzhong Liu, Min Wang. Liquid Phase Synthesis of Chiral Tartrate Ligand Library for Enantioselective Sharpless Epoxidation of Allylic Alcohols. J. Org. Chem. 2004, 69, 2042-2047. Kim H.-J.; Liu, S.Z.; Li, Q.X. Development of an enzyme-linked immunosorbent assay for the insecticide thiamethoxam. J. Agric. Food Chem, 2003, 51, 1823-1830. 编写的书目章节: Kim, H. J.; Liu, S.-Z.; Keum, Y. S.; Hwang, E. C.; Li, Q.X. 2003. Improved enzyme-linked immunosorbent assay for the insecticide imidacloprid. In: Environmental Fate and Effects of Pesticides; J.R. Coats and H. Yamamoto (Eds). ACS Symposium Series XX, Washington, DC. Series 853, 31-45.

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