高健 - 中国农业大学

个人简介

高健，2012年6月中国农业大学临床兽医学博士毕业；2012年8月至2013年12月在首农畜牧从事奶牛养殖工作；2014年1月至2016年3月在中国农业大学生物学院从事博士后研究工作；2016年3月至今在中国农业大学动物医学院临床兽医系从事教学、临床诊疗及科学研究工作。主要教学及科研方向为动物产科疾病，包括动物繁殖性疾病、围产期常见病、奶牛乳房炎、新生仔畜疾病等。主讲《大动物临床病例分析》《奶牛围产期管理》《疫病防控》等课程；参讲《兽医产科学》《兽医产科学专题》《临床兽医专业Seminar》《群发病与牧场管理》《兽医内科学专题》《临床兽医专业英语》等课程。近年来，围绕奶牛疾病方向的研究，主持国家自然基金、北京市自然基金、十三五重点研发计划项目子课题、国家自然基金联合基金子课题、省部级重点研发计划项目及企业委托项目等。以第一或通讯作者发表30余篇SCI论文和30余篇中文期刊论文，主编/副主编国家级规划教材2部，主译专业书籍2部，参编教材或专业书籍8部。担任奶牛产业扶贫工作站北京科技特派员、中国农垦标杆牧场评审组专家等。获得省部级奖2项。

研究领域

主要教学及科研方向为动物产科疾病，包括动物繁殖性疾病、围产期常见病、奶牛乳房炎、新生仔畜疾病等

近期论文

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Li, X., Xu, C., Liang, B., Kastelic, J.P., Han, B., Tong, X., Gao, J*. 2023. Alternatives to antibiotics for treatment of mastitis in dairy cows. Front Vet Sci, 10:1160350. Liang, B., Han, B., Shi, Y., Li, X., Zhao, W., Kastelic, J., Gao, J*. 2023. Effective of phage cocktail against Klebsiella pneumoniae infection of murine mammary glands. Microb Pathog 2023:106218. Liang, B., Zhao, W., Han, B., Barkema, H.W., Niu, Y.D., Liu, Y., Kastelic, J.P., Gao, J*. 2022. Biological and genomic characteristics of two bacteriophages isolated from sewage, using one multidrug-resistant and one non-multidrug-resistant strain of Klebsiella pneumoniae. Front Microbiol, 13:943279. Chen, P., Yang, J., Wu, N., Han, B., Kastelic, J.P., Gao, J*. 2022. Streptococcus lutetiensis induces autophagy via oxidative stress in bovine mammary epithelial cells. Oxid Med Cell Longev, 2022, 2549772. Cheng, J., Zhang, J., Yang, J., Yi, B., Liu, G., Zhou, M., Kastelic, J.P., Han, B*., Gao, J*. 2021. Klebsiella pneumoniae infection causes mitochondrial damage and dysfunction in bovine mammary epithelial cells. Vet Res, 52: 17. Cheng, J., Zhou, M., Nobrega, D.B., Barkema, H.W., Xu, S., Li, M., Kastelic, J.P., Shi, Y., Han, B*., Gao, J*. 2021. Genetic diversity and molecular epidemiology of outbreaks of Klebsiella pneumoniae mastitis on two large Chinese dairy farms. J Dairy Sci, 104: 762-775. Cheng, J., Zhou, M., Nobrega, D.B., Cao, Z., Yang, J., Zhu, C., Han, B*., Gao, J*. 2021. Virulence profiles of Klebsiella pneumoniae isolated from 2 large dairy farms in China. J Dairy Sci, 104: 9027-9036. Zhao, W., Shi, Y., Liu, G., Yang, J., Yi, B., Liu, Y., Kastelic, J.P., Han, B*., Gao, J*. 2021. Bacteriophage has beneficial effects in a murine model of Klebsiella pneumoniae mastitis. J Dairy Sci, 104: 3474-3484. Shi, Y., Zhao, W., Liu, G., Ali, T., Chen, P., Liu, Y., Kastelic, J.P., Han, B*., Gao, J*. 2021. Bacteriophages isolated from dairy farm mitigated Klebsiella pneumoniae-induced inflammation in bovine mammary epithelial cells cultured in vitro. BMC Vet Res, 17: 37. Chen, P., Qiu, Y., Liu, G., Li, X., Cheng, J., Liu, K., Qu, W., Zhu, C., Kastelic, J.P., Han, B*., Gao, J*. 2021. Characterization of Streptococcus lutetiensis isolated from clinical mastitis of dairy cows. J Dairy Sci, 104: 702-714. Cheng, J., Zhang, J., Han, B., Barkema, H.W., Cobo, E.R., Kastelic, J.P., Zhou, M., Shi, Y., Wang, J., Yang, R., Gao, J*. 2020. Klebsiella pneumoniae isolated from bovine mastitis is cytopathogenic for bovine mammary epithelial cells. J Dairy Sci, 103: 3493-3504. Zhuang, C., Liu, G., Barkema, H.W., Zhou, M., Xu, S., Ur Rahman, S., Liu, Y., Kastelic, J.P., Gao, J*., Han, B*. 2020. Selenomethionine suppressed TLR4/NF-kappaB pathway by activating selenoprotein S to alleviate ESBL Escherichia coli-induced inflammation in bovine mammary epithelial cells and macrophages. Front Microbiol, 11: 1461. Rakib, M.R.H., Zhou, M., Xu, S., Liu, Y, Asfandyar, K.M., Han, B*., Gao, J*. 2020. Effect of heat stress on udder health of dairy cows. J Dairy Res, 87 (3): 315.