蒲娟 - 中国农业大学

个人简介

教育经历 1998.09-2003.06 中国农业大学，动物医学，学士 2003.09-2005.06 中国农业大学，预防兽医学，硕士 2005.09-2008.06 中国农业大学，预防兽医学，博士工作经历 2008.06-2011.12 中国农业大学动物医学院，讲师 2012.01-2017.11 中国农业大学动物医学院，副教授 2017.11-至今中国农业大学动物医学院，教授 2013.02-2013.05 Nottingham University，UK，访问学者 2013.11-2014.12 St. Jude Children’s Research Hospital，USA，访问学者获奖及荣誉 2019年获得国家自然科学基金委优秀青年科学基金项目资助 2017年荣获北京市“青年教师教学基本功比赛”一等奖及最佳教案奖 2013年入选教育部新世纪优秀人才支持计划

研究领域

主要开展动物流感病毒流行病学与生态学及其机制研究，关注动物流感病毒的公共卫生学危害，追踪动物流感病毒在环境-动物-人中的流行与传播规律，揭示病毒致病及跨宿主传播作用机制，以探明流感病毒在生态圈中传播的关键要素，为科学防控动物和人间疫病提供理论依据

近期论文

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Pu J#, Wang S#, Yin Y#, Zhang G, Carter RA, Wang J, Xu G, Sun H, Wang M, Wen C, Wei Y, Wang D, Zhu B, Lemmon G, Jiao Y, Duan S, Wang Q, Du Q, Sun M, Bao J, Sun Y, Zhao J, Zhang H, Wu G, Liu J*, Webster RG*. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):548-53. Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H, Sun Y, Chang KC, Zhang R, Liu J, Pu J*. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian?influenza?virus in mammals. PLoS Pathog. 2022 Jul 6; 18(7): e1010645. Pu J#, Yin Y#, Liu J, Wang X, Zhou Y, Wang Z, Sun Y, Sun H, Li F, Song J, Qu R, Gao W, Wang D, Wang Z, Yan S, Chen M, Zeng J, Jiang Z, Sun H, Zong Y, Wang C, Tong Q, Bi Y, Huang Y, Du X, Chang KC, Liu J*. Reassortment with dominant chicken H9N2 influenza virus contributed to the fifth H7N9 virus human epidemic. J Virol. 2021 Mar 17:JVI.01578-20. Song J, Wang C, Gao W, Sun H, Jiang Z, Wang K, Ren X, Wang Z, Tong Q, Wang M, Sun H, Sun Y, Liu J, Pu J*. A D200N hemagglutinin substitution contributes to antigenic changes and increased replication of avian H9N2 influenza virus. Vet Microbiol. 2020 Jun;245:108669. Gao W, Zu Z, Liu J, Song J, Wang X, Wang C, Liu L, Tong Q, Wang M, Sun H, Sun Y, Liu J, Chang KC, Pu J*. Prevailing I292V PB2 mutation in avian influenza H9N2 virus increases viral polymerase function and attenuates IFN-β induction in human cells. J Gen Virol. 2019 Sep;100(9):1273-1281. Wang C, Wang Z, Ren X, Wang L, Li C, Sun Y, Wang M, Tong Q, Sun H, Pu J*. Infection of chicken H9N2 influenza viruses in different species of domestic ducks. Vet Microbiol. 2019 Jun;233:1-4. Li C, Wang S, Bing G, Carter RA, Wang Z, Wang J, Wang C, Wang L, Wu G, Webster RG, Wang Y, Sun H, Sun Y, Liu J, Pu J*. Genetic evolution of influenza H9N2 viruses isolated from various hosts in China from 1994 to 2013. Emerg Microbes Infect. 2017 Nov 29;6(11):e106. Pu J#, Sun H#, Qu Y, Wang C, Gao W, Zhu J, Sun Y, Bi Y, Huang Y, Chang KC, Cui J, Liu J*. M Gene Reassortment in H9N2 Influenza Virus Promotes Early Infection and Replication: Contribution to Rising Virus Prevalence in Chickens in China. J Virol. 2017 Mar 29;91(8):e02055-16. Xu G#, Zhang X#, Gao W, Wang C, Wang J, Sun H, Sun Y, Guo L, Zhang R, Chang KC, Liu J, Pu J*. Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity. J Virol. 2016 Aug 26;90(18):8105-14. Wei Y, Xu G, Zhang G, Wen C, Anwar F, Wang S, Lemmon G, Wang J, Carter R, Wang M, Sun H, Sun Y, Zhao J, Wu G, Webster RG, Liu J, Pu J*. Antigenic evolution of H9N2 chicken influenza viruses isolated in China during 2009-2013 and selection of a candidate vaccine strain with broad cross-reactivity. Vet Microbiol. 2016;182:1-7.