个人简介
何诚,教授,博士生导师,中国-东盟重大动物疫病防控专业科技创新院院长,中巴农业科技创新与服务中心协调人。2015年入选泰山学者特聘教授。
主持国家自然科学基金项目4项、科技部政府间合作专项1项、科技部重点研发计划、支撑计划6项,科技部国际交流合作项目1项,亚合基金项目、澜湄专项基金项目3项,省校、市-校产业合作项目15项。
获教育部科技进步一等奖1项、农业部丰收奖一等奖1项、二等奖1项。获得国家发明专利授权25项,转让12项。
研究领域
人兽共患病感染与免疫
霉菌毒素产毒素机制和防治技术
近期论文
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一、人兽共患病感染和免疫
Li XH, Zuo ZH, Wang YH, Hegemann JH, He C*.Polymorphic membrane protein 17G of Chlamydia psittaci mediated the invasion of bacteria to host cells by binding EGFR. Front.Immunol.2022,12:818487.
Li Q, Chen Sy, Yan ZQ, Fang HX, Wang ZX*, He C*.A novel intranasal vaccine with PmpG+MOMP induces robust protections both in respiratory tract and genital system posting Chlamydia psittaci infection.Front Vet Sci.2022.9:855447.
Md.Aminul Islam,Tuhin Das,Md. Arifur Rahman,Foysal Hossen,Mahin Reza,Sumit Kumar Barral,Md. Atiqul Haque,Cheng He*,Firoz Ahmed*A Review on Measures to Rejuvenate Immune System: Natural Mode of Protection Against Coronavirus Infection.Front. Immunol, 2022,13:837290.
Qiang Li, Xiaohui Li, Hongkun Quan, Yihui Wang, Guanggang Qu, Zhiqiang Shen, Cheng He*.IL-10 -/- Enhances DCs Immunity Against Chlamydia psittaci Infection via OX40L/NLRP3 and IDO/Treg Pathways.Front. Immunol. 2021,12:645653.
Zuo Z, Zou Y, Li Q, Guo Y, Zhang T, Wu J, He C*, Eko FO*.Intranasal immunization with inactivated chlamydial elementary bodies formulated in VCG-chitosan nanoparticles induces robust immunity against intranasal Chlamydia psittaci challenge.Scientif Reports, 2021,11(1):10389
Fang HX,Quan HK,Zhang YH,Li Q,Wang YH, Yuan S,Huang SJ,He C*.Co-Infection of Escherichia coli, Enterococcus faecalis and Chlamydia psittaci Contributes to Salpingitis of Laying Layers and Breeder Ducks.Pathogens.2021.6(10):755.
Cui L, Qu G, Chen Y, Wu Y, Wang C,Cheng H, Chen J. Polymorphic membrane protein 20G: A promising diagnostic biomarker for specific detection of Chlamydia psittaci infection. Microbial Pathogenesis. 2021,155:104882.
Chu J, Li XH, Qu GG, Wang YH, Li Q, Guo YX, Hou L, Liu J, Eko FO and He C.Chlamydia psittaci PmpD-N Exacerbated Chicken Macrophage Function by Triggering Th2 Polarization and the TLR2/MyD88/NF-κB Signaling Pathway. International Journal of Molecular Sciences.2020,21,2003.
Pan Q,Zhang Q,Chu J,Pais R,Liu SS, He C*,Eko FO*.Chlamydia abortus Pmp18.1 Induces IL-1β Secretion by TLR4 Activation through the MyD88, NF-κB, and Caspase-1 Signaling Pathways. Front. Cell. Infect. Microbiol.2017,7:514.
Liu SS, Sun W, Zhang W, Jia CQ, Shen YH, Yu JS, EI-Asharam S,He C*.A more effective recombinant HVT vaccine expressing PmpD-N of Chlamydia psittaci based on EF-1α promoter. Frontiers in Veterinary Medicine.2017.4:221.
二、霉菌毒素产毒素机制和防治技术
Haque MA, Wang F,Chen Y, Firoz A*, Siddique N, He C*. Bacillus spp. contamination: a novel risk originated from animal feed to human food chains in South-Eastern Bangladesh. Front.Microbiol.2021,12:783103.
Wang YH, Quan HQ, Li XH, Li Q, Haque MA, Shi Q, Fu Q, He C*. Contamination with Fumonisin B and Deoxynivalenol is a threat to egg safety and contributes to gizzard ulcerations of newborn chickens. Frontiers in Microbiology.2021, 12:676671.
Zuo ZH,Li Q,Guo YX,Li XH, Huang SJ, Hegemann JH,He.C*.Feed-borne Bacillus cereus exacerbates respiratory distress in birds infected with Chlamydia psittaci by inducing hemorrhagic pneumonia.Avian Pathology. 2020,49(3):1-12.
Xiaohui Li, Qiang Li, Yihui Wang , Zhenhai Han, Guanggang Qu, Zhiqiang Shen, Shujian Huang,Cheng He*.Gastric Ulceration and Immune Suppression in Weaned Piglets Associated with Feed-Borne Bacillus cereus and Aspergillus fumigatus.Toxins,2020,12(11):203.
Zhang Q; Zuo ZH; Guo YX; Zhang TY;Han ZH; Huang SJ; Karama M; Saleemi MK; Khan A;He C*.Contaminated feed-borne Bacillus cereus aggravates respiratory distress post avian influenza virus H9N2 infection by inducing pneumonia. Scientific Reports,2019,9:7231