刘金华 - 中国农业大学

个人简介

刘金华，男，博士，博士生导师，国家杰出青年科学基金获得者，国家有突出贡献中青年专家，获国务院政府特殊津贴，1997-2012年度山东省重大动物疫病防控泰山学者，教育部新世纪优秀人才。1989年于山东农业大学获学士学位，1992年于北京农业大学获预防兽医硕士学位，1997年于中国农业大学获预防兽医博士学位，2000年至2002年于日本北海道大学从事博士后研究工作。系农业部全国动物防疫专家委员会禽流感专家组副组长、卫生部人感染H7N9禽流感联防联控专家组成员、科技部禽流感科技攻关病原组专家组成员。主持国家自然科学基金项目、973计划、国家支撑计划等课题，围绕动物流感病毒遗传演化、致病机理和防控技术等开展研究工作，在Science、PNAS、Lancet、JVI等国际权威SCI杂志以第一作者和/或通讯作者发表SCI论文多篇。

研究领域

围绕动物流感病毒遗传演化、致病机理和防控技术等开展研究工作

近期论文

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Liu JH, Xiao HX, Lei FM, Zhu QY, Qin K, Zhang XW, Zhao DM, Wang G, Feng Y, J. Ma J, Liu W, Wang J, Gao GF. Highly pathogenic H5N1 influenza virus infection in migratory birds. Science. 2005, 309 (5738):1206. Sun YP, Qin K, Wang JJ, Pu J, Tang Q, Hu Y, Bi Y, Zhao X, Yang H, Shu Y, Liu JH. High genetic compatibility and increased pathogenicity of reassortants derived from avian H9N2 and pandemic H1N1/2009 influenza viruses. Proc Natl Acad SciUSA. 2011, 108(10):4164-9. Pu J, Wang S, Yin Y, Zhang G, Carter RA, Wang J, Xu G, Sun H, Wang M, Wen C, Wei Y, Wang D, Zhu B, Lemmon G, Jiao Y, Duan S, Wang Q, Du Q, Sun M, Bao J, Sun Y, Zhao J, Zhang H, Wu G, Liu JH, Webster RG. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proc Natl Acad SciUSA. 2015, 112(2):548-553. Gu J, Xie ZG, Gao ZC, Liu JH (contribute equal to first author), Korteweg C, Ye JX, Lau LT, Lu J, Gao ZF, Zhang B, McNutt MA, Lu M, Anderson VM, Gong EC, Yu AC, Lipkin WI. H5N1 infection of the respiratory tract and beyond: a molecular pathology study. The Lancet. 2007, 370 (9593):1137-11345. Yu Q, Liu LQ, Pu J, Zhao JY, Sun YP, Shen GN, Wei H, Zhu J, Zheng RF, Xiong D, Liu XD, Liu JH. Risk perceptions for avian influenza virus infection among poultry workers,China. Emerging Infectious Diseases. 2013, 19(2):313-316. Zhang Yi, Sun YP, Sun HL, Pu J, Bi YH, Shi Y, Lu XS, Li J, Zhu QY, Gao GF, Yang HC, Liu JH. A Single Amino Acid at the Hemagglutinin Cleavage Site Contributes to the Pathogenicity and Neurovirulence of H5N1 Influenza Virus in Mice. Journal of Virology. 2012 86(12):6924-6931. Sun Y, Tan Y, Wei K, Sun H, Shi Y, Pu J, Yang H, Gao GF, Yin Y, Feng W, Perez DR, Liu JH. Amino acid 316 of hemagglutinin and the neuraminidase stalk length influence virulence of H9N2 influenza virus in chickens and mice. Journal of Virology. 2013, 87(5):2963-2968. Sun HL, Sun YP, Pu J, Zhang Y, Zhu QY, Li J, Gu J, Chang KC, Liu JH. Comparative virus replication and host innate responses in human cells infected with three prevalent clades (2.3.4, 2.3.2, and 7) of highly pathogenic avian influenza H5N1 viruses. Journal of Virology. 2014, 88(1):725-729. Sun YP, Xu Q, Shen Y, Liu LQ, Wei K, Sun HL, Pu J, Chang KC, Liu JH. Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice. Journal of Virology. 2014, 88(8):4600-4604. Wei K, Sun H, Sun Z, Sun Y, Kong W, Pu J, Ma G, Yin Y, Yang H, Guo X, Chang KC, Liu JH. Influenza A virus acquires enhanced pathogenicity and transmissibility after serial passages in swine. Journal of Virology. 2014, 88(20):11981-11994