个人简介
主要利用基因敲除小鼠，从事甲状腺癌、皮肤癌、结肠癌等发病分子机制的研究，还承担干细胞与皮肤衰老和治疗、皮肤创伤愈合和各种皮肤病的相关研究，主持国家自然科学基金项目1项、上海市自然科学基金项目2项、教育部博士点基金项目1项，参与自然科学基金项目多项，还长期作为主讲教师承担《生物化学》课程的教学工作。
研究领域
肿瘤发生发展的信号机制研究
干细胞与肿瘤和衰老的关系
各种皮肤疾病的机理研究
近期论文
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Wang Q, Gao X, Yu T, Yuan L, Dai J, WangW, Chen G, Jiao C, Zhou W, Huang Q, Cui L, Zhang P, Moses RE, Yang J, Chen F,Fu J, Xiao J, Li L, Dang Y, Li X.REGγ Controls Hippo Signaling and Reciprocal NF-κB-YAP Regulation toPromote Colon Cancer. Clinical Cancer Research 2018;24(8):2015-2025.（并列通讯作者）
Li L,Dang Y, Zhang J, et al. REGγis critical for skin carcinogenesis by modulating the Wnt/β- catenin pathway.Nature Communications2015;6:6875.(并列第一作者）
Xu P, Dang Y, Wang L, Liu X, Ren X, Gu J, Liu M, Dai X, Ye X.Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.Cancer Lett. 2016;383(2):161-170.(并列第一作者）
Zhai Y,Dang Y, Gao W, Zhang Y, Xu P, Gu J, Ye X.P38 and JNK signal pathways are involved in the regulation of phlorizin against UVB-induced skin damage.Experimental Dermatol2015; 24(4):275-9.(并列第一作者）
Li K, Guo Q, Yang J, Chen H, Hu K, Zhao J, Zheng S, Pang X, Zhou S, Dang Y, Li L.FOXD3 is a tumor suppressor of colon cancer by inhibiting EGFR-Ras-Raf-MEK-ERK signal pathway.Oncotarget2017;8(3):5048-5056.（并列通讯作者）
Yang X, Li L, Huang Q, Xu W, Cai X, Zhang J, Yan W, Song D, Liu T, Zhou W, Li Z, Yang C,Dang Y*, Xiao J*. Wnt signaling through Snail1 and Zeb1 regulates bone metastasis in lung cancer.American Journal of Cancer Research2015; 5(2):748-55.（并列通讯作者）
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y(*), Liu T(*), Li L(*). REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway. Experimental Dermatology, 2017, 26(11):1118-1124.（并列通讯作者）
Dang Yongyan, Liu Bei, Xu Peng, Zhu Pingya, Ye Xiyun, Liu Mingyao. Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.Plos ONE2014；9(3): e89835.（第一作者）
Xiyun Ye, Luyang Wang,Yongyan Dang*, Bei Liu, Di Zhao. Investigation of the 1064nm Q-switched Nd:YAG laser on collagen expression in an animal model. Photomedicine and Laser Surgery; 30: 604-609; 2012. (通讯作者）
Qin Y, Qin X, Xu P, Zhi Y, Xia W, Dang Y(*), Gu J(*), Ye X(*). Potential role of S100A8 in skin rejuvenation with the 1064-nm Q-switched Nd:YAG laser.Lasers Med Sci 2018; 33(3):581-588.（并列通讯作者）
Ren X, Ge M, Qin X, Xu P, Zhu P,Dang Y*, Gu J, Ye X.S100a8/NF-κB signal pathway is involved in the 800-nm diode laser-induced skin collagen remodeling. Lasers Med Sci. 2016;31(4):673-8.（并列通讯作者）
Li Lei，Zhao D, Wei H, Yao L,Dang Y, Amjad A,et al. REGγ deficiency promotes premature aging via the casein kinase 1 pathway. PNAS; 110: 11005-11010; 2013.
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