个人简介
教育背景及工作经历
2014.01 - 至今:华东师范大学 生命科学学院 副教授
2009.12 - 2013.11:美国Wake Forest Medical Center神经与解剖系 博士后
2004.09 - 2009.07:华东师范大学 生命科学学院 生理学专业 博士
2000.09 - 2004.07:内蒙古大学生命科学学院 生物基地班 本科
奖励情况
2012: Mary A. Bell Awards for outstanding poster presentations at the NC Chapter of the Society for Neuroscience Fall Research Day
2012: Society of Neuroscience Chapter Travel Award Nominee
2010: Wake Forest University Postdoctoral Development Award
2009:上海市优秀毕业生
研究领域
人和动物通过多种外周感觉器官获得感觉信息,大脑整合这些信息,然后依靠感知得到的信息和记忆中的经验做出决策,最终转化为运动行为。我门的研究聚焦于理解大脑如何加工整合多种感觉信息并转化为决策和运动指令。同时建立感觉运动障碍的动物模型,开发多感觉训练诱导感觉运动障碍康复的方法,并研究多感觉康复训练过程的神经可塑性机制
近期论文
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Yu L,Hu J,Shi C,Zhou L,Tian M,Zhang J,Xu J# (2021) The causal role of auditory cortex in auditory working memory. Elife Apr 29;10:e64457.
Zheng M,Xu J,Keniston L,Wu J,Chang S,Yu L (2021) Choice-dependent cross-modal interaction in the medial prefrontal cortex of rats. Mol Brain. Jan 15;14(1):13.
Yu L, Cuppini C, Xu J, Rowland BA, Stein BE (2019) Cross-Modal Competition: The Default Computation for Multisensory Processing. J Neurosci. 20;39(8):1374-1385.
Xu J, Bi T, Wu J, Meng F, Wang K, Hu J, Han X, Zhang J, Zhou X, Keniston L, Yu L (2018) Spatial receptive field shift by preceding cross-modal stimulation in the cat superior colliculus. J Physiol. 596(20):5033-5050.
Xu J#*, Yu L.*, Rowland BA, Stein BE. (2017) The normal environment delays the development of multisensory integration. Scientific Report. 7(1):4772.
Xu, J, Bi, T., Keniston, L., Zhang, J., Zhou, X., Yu, L.# (2017) Deactivation of Association Cortices Disrupted the Congruence of Visual and Auditory Receptive Fields in Superior Colliculus Neurons. Cerebral Cortex. 27(12):5568-5578.
Yu, L.,Xu, J., Rowland, B.A., and Stein, B.E. (2016). Multisensory Plasticity in Superior Colliculus Neuronsis Mediated by Association Cortex. Cerebral cortex. 26(3):1130-7.
Xu J, Yu L, Stanford TR, Rowland BA, Stein BE (2015) What does a neuron learn from multisensory experience? J Neurophysiol.Feb 1;113(3):883-9.
Xu J, Sun X, Zhou X, Zhang J, Yu L (2014) The cortical distribution of multisensory neurons was modulated by multisensory experience. Neuroscience Jul 11;272:1-9.
Xu J, Yu L, Rowland BA, Stanford TR, Stein BE (2014) Noise-rearing disrupts the maturation of multisensory integration. Eur J Neurosci 39, 602-613.
Xu J, Yu L, Rowland BA, Stanford TR, Stein BE (2012) Incorporating cross-modal statistics in the development and maintenance of multisensory integration. J Neurosci 32(7):2287-2298.
Xu J, Yu L, Cai R, Zhang J, Sun X (2010) Early continuous white noise exposure alters auditory spatial sensitivity and expression of GAD65 and GABAA receptor subunits in rat auditory cortex. Cereb Cortex 20:804-812.
Xu J, Yu L, Zhang J, Cai R, Sun X (2010) Early continuous white noise exposure alters l-alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunit glutamate receptor 2 and gamma-aminobutyric acid type a receptor subunit beta3 protein expression in rat auditory cortex. J. Neurosci. Res. 88:614-619.
Xu J, Yu L, Cai R, Zhang J, Sun X (2009) Early auditory enrichment with music enhances auditory discrimination learning and alters NR2B protein expression in rat auditory cortex. Behav Brain Res 196:49-54.
Yu L, Xu J, Rowland BA, Stein BE (2013) Development of cortical influences on superior colliculus multisensory neurons: effects of dark-rearing. Eur J Neurosci. Mar 37(10):1594-601.
Yu L, Rowland BA, Xu J, Stein BE (2013) Multisensory plasticity in adulthood: cross-modal experience enhances neuronal excitability and exposes silent inputs.J Neurophysiol. 109(2):464-74.
Cai R, Zhou X, Guo F, Xu J, Zhang J, Sun X (2010). Maintenance of enriched environment-induced changes of auditory spatial sensitivity and expression of GABA, NMDA, and AMPA receptor subunits in rat auditory cortex. Neurobiol Learn Mem 94: 452-460.
Cai R, Guo F, Zhang J, Xu J, Cui Y, Sun X (2009) Environmental enrichment improves behavioral performance and auditory spatial representation of primary auditory cortical neurons in rat. Neurobiol Learn Mem 91:366-376.
Xu F, Cai R, Xu J, Zhang J, Sun X (2007) Early music exposure modifies GluR2 protein expression in rat auditory cortex and anterior cingulate cortex. Neurosci Lett 420:179-183.