徐岷涓 - 上海交通大学 - 系统生物医学研究院

个人简介

学习经历 1.2001/9–2006/7，北京大学，生药学，博士 2.1997/9–2001/7，北京大学，药学，学士工作经历 1.2010/3-至今，上海交通大学，系统生物医学研究院，副研究员 2.2008/5-2010/2，北京大学，天然药物与仿生药物国家重点实验室，助理研究员 3.2006/9-2008/4，德国维尔茨堡大学，博士后，洪堡学者

研究领域

结构复杂、活性多样的天然产物是现代药物的重要组成部分和新药发现的重要来源，徐岷涓博士主要研究领域为天然药物化学和药学，包括新结构类型的发现、新生物活性的筛选、新生物合成机理的解析，并结合大规模代谢网络建模构建药物的生物合成体系，为创新海洋药物研究服务。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Combinatory Biosynthesis of Prenylated 4 Hydroxybenzoate Derivatives by Overexpression of the Substrate-Promiscuous Prenyltransferase XimB in Engineered E. coli Bei-Bei He(#); Xu-Liang Bu(#); Ting Zhou; Shu-Ming Li; Min-Juan Xu(*); Jun Xu(*) ACS Synth. Biol., 2018, 7: 2094~2104 2. Deciphering the streamlined genome of Streptomyces xiamenensis 318 as the producer of the anti-fibrotic drug candidate xiamenmycin Xu Min Juan(#); Wang Jia Hua; Bu Xu Liang; Yu He Lin; Li Peng; Ou Hong Yu; He Ying; Xu Fang Di; Hu Xiao Yan; Zhu Xiao Mei; Ao Ping; Xu Jun(*) Scientific Reports, 2016, 6: 18977 3. Structural diversity of anti-pancreatic cancer capsimycins identified in mangrove-derived Streptomyces xiamenensis 318 and post-modification via a novel cytochrome P450 monooxygenase Yu He Lin(#); Jiang Shu Heng; Bu Xu Liang; Wang Jia Hua; Weng Jing Yi; Yang Xiao Mei; He Kun Yan; Zhang Zhi Gang; Ao Ping; Xu Jun(*); Xu Min Juan(*) Scientific Reports, 2017, 7(1): 40689 4. Total synthesis and stereochemical revision of xiamenmycin A Jiao Xiaozhen(#); Yao Yangyang; Yang Beibei; Liu Xiaoyu; Li Xiaoyu; Yang Hongguang; Li Li; Xu Jun; Xu Minjuan(*); Xie Ping(*) Organic and Biomolecular Chemistry, 2016, 14(5): 1805~1813 5. Xiamenmycin Attenuates Hypertrophic Scars by Suppressing Local Inflammation and the Effects of Mechanical Stress Liu, Xiao-Jin(#); Xu, Min-Juan(#); Fan, Si-Teng; Wu, Zheng; Li, Jun; Yang, Xiao-Mei; Wang, Ya-Hui; Xu, Jun(*); Zhang, Zhi-Gang(*) Journal of Investigative Dermatology, 2013, 133(5): 1351~1360 6. Characterization of the Xiamenmycin Biosynthesis Gene Cluster in Streptomyces xiamenensis 318 Yang, Yong(#); Fu, Ling; Zhang, Jinlong; Hu, Linghan; Xu, Minjuan(*); Xu, Jun(*) PLos One, 2014, 9(6): e99537 7. In Vivo Metabolism Study of Xiamenmycin A in Mouse Plasma by UPLC-QTOF-MS and LC-MS/MS Lei Feng(#); Gao Du; Zhang Xi; Xu Jun; Xu Min Juan(*) Marine Drugs, 2015, 13(2): 727~740 8. Identification and Characterization of an Anti-Fibrotic Benzopyran Compound Isolated from Mangrove-Derived Streptomyces xiamenensis Xu, Min-Juan(#); Liu, Xiao-Jin(#); Zhao, Yi-Lei; Liu, Dong; Xu, Zhen-Hao; Lang, Xiao-Meng; Ao, Ping; Lin, Wen-Han; Yang, Song-Lin; Zhang, Zhi-Gang(*); Xu, Jun(*) Marine Drugs, 2012, 10(3): 639~654