马钢 - 上海交通大学 - 生命科学技术学院

个人简介

上海交通大学副研究员，Bio-X研究院发育功能基因组学组副组长，博士，硕导。安徽科技学院学士，长春军需大学硕士，上海交通大学博士。

研究领域

A-1型短指(趾)症致病基因IHH在骨发育中的功能分析；Wnt，BMP及Hedgehog等信号通路在皮肤及毛囊干细胞发育及相关疾病发生中的作用；合成生物学中特定生物学功能模块的设计与开发，尤其关注调节基因表达和重要生物质代谢途径的元器件的开发与应用。

近期论文

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Sixia Huang#, Xuming Zhu#, Yanfang Liu, Yixin Tao, Guoyin Feng, Lin He, Xizhi Guo*, Gang Ma*. Wls is Expressed in the Epidermis and Regulates Embryonic Hair Follicle Induction in Mice. PLoS ONE 7(9): e45904. doi:10.1371/journal.pone.0045904. Hui-Yi Kua#, Huijuan Liu#, Wai Fook Leong#, Lili Li, Deyong Jia, Gang Ma, Yuanyu Hu, Xueying Wang, Jenny F. L. Chau, Ye-Guang Chen, Yuji Mishina, Sharon Boast, James Yeh, Li Xia, Guo-Qiang Chen, Lin He, Stephen P. Goff, and Baojie Li*. c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16 INK4a expression. Nature Cell Biology 2012, 7: 727-737. Gang Ma#, Lili Li#, Yuanyu Hu, Jenny Fung Ling Chau, Bi Jin Au, Deyong Jia, Huijuan Liu, James Yeh, Lin He, Aijun Hao*, and Baojie Li*. Atypical Atm-p53 genetic interaction in osteogenesis is mediated by Smad1 signaling. Journal of Molecular Cell Biology. Journal of Molecular Cell Biology 2012; 4(2):118-20. Ma G, Yu J, Xiao Y, Chan D, Gao B*, Hu J, He Y, Guo S, Zhou J, Zhang L, Gao L, Zhang W, Kang Y, Cheah KS, Feng G, Guo X, Wang Y, Zhou CZ, He L*. INDIAN HEDGEHOG mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels. Cell Research 2011; 21(9):1343-57. Gao B#, Hu J#, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L*, Cheah KS, Chan D*. A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature 2009; 458, 1196-1200. Ma G, Xiao Y, He L*. Recent progress in the study of Hedgehog signaling. Journal of Genetics and Genomics 2008; 35(3): 129-137. Ma G#, He Z#, Fang W, Tang W, Huang K, Li Z, He G, Xu Y, Feng G, Zheng T, Zhou J, He L*, Shi Y*. The Ser9Gly Polymorphism of the Dopamine D3 Receptor Gene and Risk of Schizophrenia: An Association Study and a large Meta-Analysis. Schizophrenia research 2008; 101:26-35. Ma G#, Shi Y#*, Tang W, He Z, Huang K, Li Z, He G, Feng G, Li H, He L*. An association study between the genetic polymorphisms within TBX1 and schizophrenia in the Chinese population. Neurosci Lett 2007; 425(3):146-150.