梁如冰 - 上海交通大学 - 生命科学技术学院

个人简介

梁如冰，博士，副研究员。2003年硕士毕业于北京师范大学细胞生物学研究所教育部重点实验室，2007年获上海交通大学生物化学与分子生物学博士学位。2007年3月起在上海交通大学生命科学技术学院生物技术系(微生物代谢国家重点实验室)功能基因组学实验室工作。先后赴UCSD、哈佛大学做访问学者与博士后工作。主要从事微生物染色体改造与功能研究、基因调控、工程菌株构建与代谢工程等方面的研究。目前已发表论文13篇，已申请专利2项。主持国家自然科学基金与教育部基金等多项，参与多项973，863等项目研究，是国家微生物代谢重点实验室、教育部创新团队和国家自然科学基金创新研究群体的骨干成员，上海市生物工程学会和上海市微生物学会的会员。曾先后获得“上海交通大学晨星青年学者奖励计划”和“上海高校选拔培养优秀青年教师科研专项基金”等奖励。

研究领域

微生物条件性基因表达调控、基因改造与功能研究及代谢工程

近期论文

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Zheng Lu*, Rubing Liang*, Jianhua Liu. Necessity not redundancy: the function of RNase HIII in Chlamydia pneumoniae. Molecular Microbiology. 2012 (* Co-first author) Rubing Liang, Jing Zhou, Wenhua Wang, Jianhua Liu. Construction of an estrogen detection bacteria assay based on an estrogen-sensitive intein. Applied and Environmental Microbiology, 2011, 77(7): 2488-2495. Rubing Liang, Jianhua Liu. Construction and appliance of the temperature-sensitive Pseudomonas strain using TS intein. Applied and Environmental Microbiology Rubing Liang, Jianhua Liu. Method for the obtainment of the intermediate products in the essential biosynthesis pathway of Escherichia coli. Analytical Biochemistry Rubing Liang, Jianhua Liu. Scarless and sequential gene modification in Pseudomonas using PCR product flanked by short homology regions. BMC Microbiology, 2010, 10 (1): 209 Jing Zhou, Rubing Liang#, Jianhua Liu, Wenhua Wang. Detection of typical environmental estrogens using new estrogenic-sensitive genetic strain assay, Chinese Journal of Environmental Engineering, 2010, 10(4), 2387-2390. (# Corresponding author) Xipeng Liu, Jing-Li Hou, Chunpeng Li, Yu-Feng liu, Rubing Liang, Jianhua Liu. Expression and Characterization of Thymine-DNA Glycosylase from Aeropyrum pernix. Protein Expression and Purification, 2010, 70(1):1-6 Rubing Liang, Jianhua Liu. In-frame deletion of Escherichia coli essential genes in complex regulon. BioTechniques, 2008, 44 (2): 209-215 Rubing Liang, Jianhua Liu. New Escherichia coli strain construction for environmental estrogens screen based on estrogen-sensitive intein. Journal of Biotechnology, 2008, 136: S637 Rubing Liang, Jianhua Liu. Metabolic engineering of Escherichia coli for L-threonine high production. Journal of Biotechnology, 2008, 136: S309 Rubing Liang, Xipeng Liu, Dongli Pei, Jianhua Liu. Biochemical characterization of Ribonuclease HII and Ribonuclease HIII from Chlamydia pneumonia AR39. Microbiology, 2007, 153 (Pt 3): 787-793 Rubing Liang, Xipeng Liu, Jianhua Liu, Qiushi Ren, Peiji Liang, Zhixin Lin, Xiangming Xie. A novel strategy to create temperature-sensitive mutants with T7-expression system in Escherichia coli, Journal of Microbiological Methods, 2007, 68(3): 497-506 Xipeng Liu, Yang Zhang, Rubing Liang, Jing-Li Hou, Jianhua Liu. Characterization of the 3' exonuclease of Chlamydophila pneumoniae endonuclease IV on double-stranded DNA and the RNA strand of RNA/DNA hybrid. Biochemistry and Biophysics Research Communication, 2007, 361 (4): 987-993.