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Cheng Q, Cao B, Yao F, Li J, Deng Z, You D*. Regulation of DNA phosphorothioate modifications by the transcriptional regulator DptB in Salmonella. Molecular Microbiology 2015, doi: 10.1111/mmi.13096. Cao B, Zheng X, Cheng Q, Yao F, Zheng T, Babu IR, Zhou H, Dedon PC, You D*. In vitro analysis of phosphorothioate modification of DNA reveals substrate recognition by a multiprotein complex. Scientific Reports 2015, doi: 10.1038/srep12513. Cao B, Cheng Q, Gu C, Yao F, DeMott MS, Zheng X, Deng Z, Dedon PC, You D*. Pathological phenotypes and in vivo DNA cleavage by unrestrained activity of a phosphorothioate-based restriction system in Salmonella. Molecular Microbiology 2014, 93(4):776-785. Cao B, Chen C, DeMott MS, Cheng Q, Clark TA, Xiong X, Zheng X, Butty V, Levine SS, Yuan G, Boitano M, Luong K, Song Y, Zhou X, Deng Z, Turner SW, Korlach J, You D*, Wang L*, Chen S*, Dedon PC. Genomic mapping of phosphorothioates reveals partial modification of short consensus sequences. Nature Communications 2014, 5: 3951. Zhu T, Cheng X, Liu Y, Deng Z, You D*. Deciphering and engineering of the final step halogenase for improved chlortetracycline biosynthesis in industrial Streptomyces aureofaciens. Metabolic Engineering 2013, 19:69-78. Zhang C, Kong L, Liu Q, Lei X, Zhu T, Yin J, Lin B, Deng Z, You D*. In vitro characterization of echinomycin biosynthesis: formation and hydroxylation of L-tryptophanyl-S-enzyme and oxidation of (2S,3S) β-hydroxytryptophan. PLoS One 2013, 8 (2): e56772. Lei X, Kong L, Zhang C, Liu Q, Yao F, Zhang W, Deng Z, You D*. In vivo investigation of the substrate recognition capability and activity affecting amino acid residues of glycosyltransferase FscMI in biosynthesis of candicidin. Molecular BioSystems 2013, 9 (3): 422-430. Cao B, Yao F, Zheng X, Cui D, Shao Y, Zhu C, Deng Z, You D*. Genome mining of the biosynthetic gene cluster of the polyene macrolide antibiotic tetramycin and characterization of a P450 monooxygenase involved in the hydroxylation of the tetramycin B polyol segment. ChemBioChem 2012, 13(15):2234-42. Zhang W, Wang L, Kong L, Wang T, Chu Y, Deng Z, You D*. Unveiling the post-PKS redox tailoring steps in biosynthesis of the type II polyketide antitumor antibiotic xantholipin. Chemistry & Biology 2012, 19(3):422-32. (Cell Press journals) Liu Q, Yao F, Chooi Y, Kang Q, Xu W, Li Y, Shao Y, Shi Y, Deng Z, Tang Y*, You D*. Elucidation of piericidin A1 biosynthetic locus revealed a thioesterase-dependent mechanism of α-pyridone ring formation. Chemistry & Biology 2012, 19(2):243-53. (Cell Press journals) Wang T, Bai L, Zhu D, Lei X, Liu G, Deng Z, You D*. Enhancing macrolide production in Streptomyces by coexpressing three heterologous genes. Enzyme and Microbial Technology 2012, 50: 5-9. (Comments by Faculty of 1000) Xu T, Yao F, Zhou X, Deng Z*, You D*. A novel host-specific restriction system associated with DNA backbone S-modification in Salmonella. Nucleic Acids Research 2010, 38(20): 7133-41. (selected as feature article) Yao F, Xu T, Zhou X, Deng Z*, You D*. Functional analysis of spfD gene involved in DNA phosphorothioation in Pseudomonas fluorescens Pf0-1. FEBS Letters 2009, 583(4):729-33. Chen W, Huang T, He X, Meng Q, You D, Bai L, Li J, Wu M, Li R, Xie Z, Zhou H, Zhou X, Tan H, Deng Z*. Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H. The Journal Biological Chemistry 2009, 284(16): 10627-38. Xu T, Liang J, Chen S, Wang L, He X, You D, Wang Z, Li A, Xu Z, Zhou X, Deng Z*. DNA phosphorothioation in Streptomyces lividans: mutational analysis of the dnd locus. BMC Microbiology 2009, 9: 41. Zhou Y, Meng Q, You D, Li J, Chen S, Ding D, Zhou X, Zhou H, Bai L, Deng Z*. Selective removal of aberrant extender units by a type II thioesterase for efficient FR-008/candicidin biosynthesis in Streptomyces sp. strain FR-008. Applied Environmental Microbiology 2008, 74(23):7235-42. You D*, Xu T, Yao F, Zhou X, Deng Z*. Direct evidence that ThiI is an ATP pyrophosphatase for the adenylation of uridine in 4-thiouridine biosynthesis. ChemBioChem 2008, 9(12):1879-82. Wang L, Chen S, Xu T, Taghizadeh K, Wishnok JS, Zhou X, You D, Deng Z*, Dedon PC*. Phosphorothioation of DNA in bacteria by dnd genes. Nature Chemical Biology 2007, 3(11): 709-10. (Comments by Nat Chem Biol, C&EN, Nature China) Chen Q, You D, Liang Y, Su X, Gu X, Luo M, Zheng X*. Crystal structure of Thermoanaerobacter tengcongensis hypoxanthine-guanine phosphoribosyl transferase L160I mutant--insights into inhibitor design. FEBS Journal 2007, 274(17):4408-15. You D, Wang L, Yao F, Zhou X, Deng Z*. A novel DNA modification by sulfur: DndA is a NifS-like cysteine desulfurase capable of assembling DndC as an iron-sulfur cluster protein in Streptomyces lividans. Biochemistry 2007, 46(20):6126-33.