当前位置: X-MOL首页全球导师 国内导师 › 夏小霞

个人简介

上海交通大学特别研究员,博士生导师。2009年1月获韩国科学技术院(KAIST) 化学与生物分子工程博士学位,之后在韩国KAIST及美国Tufts大学从事博士后研究,于2012年9月加入上海交通大学,并被授予上海高校特聘教授(东方学者)称号,且入选上海市浦江人才计划(A类)。 主要研究先进功能材料的设计与微生物合成,在PNAS、Advanced Materials、Biomacromolecules等国际期刊发表SCI研究论文42篇,代表性人工蜘蛛丝研究成果被Nature Chemical Biology和麻省理工学院出版的Technology Review以“新闻和观点”和专题等形式作了评论和推介,获得美国、澳大利亚等国家发明专利授权10余项,应邀在包括2017年国际合成生物学大会、2015年哥本哈根生物科学会议等有影响的国际会议作学术报告10余次,并担任国际期刊Biotechnology Journal及ACS Biomaterials Science&Engineering编委。

研究领域

先进材料的仿生合成 新型智能生物材料的设计与合成 蛋白生物材料的高效生物制造及应用

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Zhou Z†, Zhang S†, Marelli B*, Xia XX*, Tao TH*. Engineering the future of silk materials through adaptable modification and advanced manufacturing. Adv Mater, 2018, DOI: 10.1002/adma.201706983. Jiang J†, Zhang S†, Qian Z, Qin N, Song W, Sun L, Zhou Z, Shi Z, Chen L, Li X, Mao Y, Kaplan DL, Gilbert Corder SN, Chen X, Liu M, Omenetto FG, Xia XX*, Tao TH*. Protein bricks: 2D and 3D bio-nanostructures with shape and function on demand. Adv Mater, 2018, DOI: 10.1002/adma.201705919 (Selected as inside back cover). Chen XF, Xia XX, Lee SY, Qian ZG*. Engineering tunable biosensors for monitoring putrescine in Escherichia coli. Biotechnol Bioeng, 2018, 115(4): 1014-1027. Yu JL, Xia XX, Zhong JJ*, Qian ZG*. Enhanced production of C5 dicarboxylic acids by aerobic-anaerobic shift in fermentation of engineered Escherichia coli. Process Biochem, 2017, 62: 53-58. Jiang H, Xia XX, Feng Y, Zhong JJ, Qian ZG*. Development of a robust system for high-throughput colorimetric assay of diverse amino acid decarboxylases. Process Biochem, 2017, 60: 27-34. Yu JL, Xia XX, Zhong JJ*, Qian ZG*. A novel synthetic pathway for glutarate production in recombinant Escherichia coli. Process Biochem, 2017, 59: 167-171. Huang SC†, Qian ZG†, Dan AH, Hu X, Zhou ML, Xia XX*. Rational design and hierarchical assembly of a genetically engineered resilin-slik copolymer results in stiff hydrogels. ACS Biomater Sci Eng, 2017, 3(8): 1576-1585. Qiao X, Qian Z, Li J, Sun H, Han Y, Xia XX, Zhou J, Wang C, Wang Y*, Wang C*. Synthetic engineering spider silk fiber as implantable optical waveguides for low-loss light guiding. ACS Appl Mater Interfaces, 2017, 9(17): 14665-14676. Chen L, Zhou ML, Qian ZG, Kaplan DL, Xia XX*. Fabrication of protein films from genetically engineered silk-elastin-like proteins by controlled cross-linking. ACS Biomater Sci Eng, 2017, 3(3): 335-341. Zhou ML, Qian ZG, Chen L, Kaplan DL, Xia XX*. Rationally designed redox-sensitive protein hydrogels with tunable mechanical properties. Biomacromolecules, 2016, 17(11): 3508-3515. Peng Q†, Zhang Y†*, Lu L, Shao H, Qin K, Hu X, Xia XX*. Recombinant spider silk from aqueous solutions via a bio-inspired microfluidic chip. Sci Rep, 2016, 6: 36473. Qin N†, Zhang S†, Jiang J, Corder SG, Qian Z, Zhou Z, Lee W, Liu K, Wang X, Li X, Shi Z, Mao Y, Bechtel HA, Martin MC, Xia XX, Marelli B, Kaplan DL, Omenetto FG*, Liu M*, Tao TH*. Nanoscale probing of electron-regulated structural transitions in silk proteins by near-field IR imaging and nano-spectroscopy. Nat Commun, 2016, 7: 13079. Huang W, Tarakanova A, Dinjaski N, Wang Q, Xia XX, Chen Y, Wong JY, Buehler MJ, Kaplan DL*. Design of multistimuli responsive hydrogels using integrated modeling and genetically engineered silk-elastin-like-proteins. Adv Funct Mater, 2016, 26(23): 4113-4123. Yang YX, Qian ZG, Zhong JJ*, Xia XX*. Hyper-production of large proteins of spider dragline silk MaSp2 by Escherichia coli via synthetic biology approach. Process Biochem, 2016, 51(4): 484-490. (Editors’ Choice paper) Qian ZG†, Zhou ML†, Song WW, Xia XX*. Dual thermosensitive hydrogels assembled from the conserved C-terminal domain of spider dragline silk. Biomacromolecules, 2015, 16(11): 3704-3711. Qi K, Xia XX, Zhong JJ*. Enhanced anti-oxidative activity and lignocellulosic ethanol production by biotin addition to medium in Pichia guilliermondii fermentation. Bioresource Technol, 2015, 189: 36-43. Yu JL, Xia XX, Zhong JJ*, Qian ZG*. Direct biosynthesis of adipic acid from a synthetic pathway in recombinant Escherichia coli. Biotechnol Bioeng, 2014, 111(12): 2580-2586. Xu YN, Xia XX, Zhong JJ*. Induction of ganoderic acid biosynthesis by Mn2+ in static liquid cultivation of Ganoderma lucidum. Biotechnol Bioeng, 2014, 111(11) :2358-2365. Qi K, Zhong JJ*, Xia XX*. Triggering respirofermentative metabolism in the Crabtree-negative yeast Pichia guilliermondii by disrupting the CAT8 Gene. Appl Environ Microbiol, 2014, 80(13): 3879-3887.

推荐链接
down
wechat
bug