个人简介
教授, 博士生导师。1997年北京大学博士毕业,1997年至2004年11月分别到德国哥廷根大学和德国灵长中心做博士后,美国康涅狄格大学访问学者,美国犹他大学Research Fellow,美国天普大学Associate Scientist。2004年11月至今任上海交通大学生命科学技术学院教授、博士生导师。曾主持上海市浦江人才计划基金、教育部高等学校博士点基金和教育部留学回国人员基金。现主持国家自然科学基金重点项目, 国家自然科学基金重大研究计划培育项目, 农业部重大项目子课题和科技部重大研究计划子课题。已在Nature Cell Biology, Molecular Biology of the Cell, Developmental Biology, Cellular Signalling, Journal of Cellular Physiology, Biology of Reproduction, Cell Proliferation, Fertility and Sterility, Human Reprodution, Journal of Endocrinology等重要学术刊物上发表论文近50篇。受邀为FEBS J, Reproductive Biology and Endocrinology, DNA and Cell Biology 等杂志撰写综述。最新研究成果—发现成年哺乳动物卵巢内具有自我更新和分化潜能的生殖干细胞,开辟了一个崭新研究领域。Science,Nature, Nature Medicine和众多家杂志刊发评论文章,Nature China将这一成果列入最新研究亮点。为国际Faculty of 1000 Biology推荐论文,世界各大媒体(包括《纽约时报》、《华盛顿邮报》、《路透社》、《美国广播公司新闻》(ABC News)、《泰晤士报》(The Times)等)纷纷报道。现为美国Reproductive Biology and Endocrinology 杂志Adviser,美国American Journal of Biochemistry and Biotechnology 杂志客座编辑,香港研究资助局大学教育资助委员会国际评委, 中国组织工程研究与临床康复杂志编委,Stem Cell Reviews and Reports, Cell Proliferation, Developmental Dynamics, Cloning and Stem Cells, DNA and Cell Biology 等十余家杂志特邀审稿人。
近期论文
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Zou K, Yuan Z, Yang Z, Luo H, Sun K, Zhou L, Xiang J, Shi L, Yu Q, Zhang Y, Hou R, Wu J. Production of offspring from a germline stem cell line derived from ovaries. Nature Cell Biology 2009; 11: 631-636 (通讯作者, Table of Contents Cover Story). Yuan Z., Hou R., Wu J. Generation of mice by transplantation of an adult spermatogonial cell line after cryopreservation. Cell proliferation 2009; 42: 123-131 (通讯作者) Zhang Y., Wu J. Molecular cloning and characterization of a new gene, Oocyte-G1. J cell Physiol 2009; 218: 75-83 (通讯作者) (Cover Story) Shi L, Wu J. Epigenetic regulation in mammalian preimplantation embryo development. Reproductive Biology and Endocrinology 2009; 7:59 (通讯作者) Yu Q., Wu J. Involvement of cyclins in mammalian spermatogenesis. Mol Cell Biochem. 2008; 315(1-2): 17-24 (通讯作者). Yang Z., Wu J. Mouse Dynein Axonemal Intermediate Chain 2: Cloning and Expression. DNA and Cell Biology 2008; 27: 479-488 (通讯作者) (Cover Story) Wu J., Zhang Y., Tian G.G., Zou K., Lee C.M., Yu Q., Yuan Z. Short-type PB-cadherin promotes self-renewal of spermatogonial stem cells via multiple signaling pathways. Cell Signal. 2008; 20: 1052-1060 (通讯作者) Zhang Y., Yang Z., Wu J. Signaling pathways and preimplantation development of mammalian embryos. FEBS J 2007; 274: 4349-4359 (通讯作者) Yang Z., Wu J. MicroRNAs and Regenerative Medicine. DNA and Cell Biology 2007; 26: 257-246 (通讯作者) Wu J., Tian Q. Role of follicle stimulating hormone and epidermal growth factor in the development of porcine preantral follicle in vitro. Zygote 2007; 15: 233-240 (通讯作者) Wu J., Xu B., Wang W. Effects of luteinizing hormone and follicle stimulating hormone on the developmental competence of porcine preantral follicle oocytes grown in vitro. J Assist Reprod Genet 2007; 24: 419-424 (通讯作者) Yang, Z., Wu, J. Small RNAs and development. Med Sci Monit 2006; 12: RA125-129 (通讯作者)