李婧 - 上海交通大学 - 生命科学技术学院

个人简介

李婧，教授，博士生导师。2007年获上海交通大学生物信息学方向博士学位, 2007年至2010年为美国范德堡大学生物医学信息学系博士后。2010年起历任上海交通大学生物信息与生物统计学系副教授、教授。研究方向聚焦高通量蛋白质组生物信息学，围绕关键性、致病性蛋白质的精准鉴定与注释的科学问题，开发了系列生物信息学与统计学方法与工具，显著推动蛋白质组学在生物重要表型、复杂疾病机理解析以及精准治疗诊断的应用。累计在Nature Biotechnology、Genome Biology、Molecular Systems Biology、Bioinformatics、Molecular & Cellular Proteomics、Journal of Proteome Research、Journal of Proteomics等专业领域重要期刊发表SCI论文20余篇，获授权发明专利2项、软件著作权4项。获上海市浦江人才计划（A类）与上海交通大学SMC-晨星优秀青年教师（A类）；2016年起担任中国蛋白质组学专业委员会（CNHUPO）委员。

研究领域

蛋白质组学生物信息学组学数据统计生物信息软件与数据库开发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

B.Liu, S.Jiang, M.Li, X.Xiong, M.Zhu, D.Li, L.Zhao, L.Qian, L.Zhai, J.Li, H.Lu, S.Shan, J.Lin, Y.Lu, X.Li, M.Tan. Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN. Nature Communications. 9(1),4770, 2018. X.Yi,B.Wang, Z.An, F.Gong, J.Li*, Y. Fu*. Quality control of single amino acid variations detected by tandem mass spectrometry. Journal of Proteomics. 187,144-151, 2018. W.Wang, R. Mauleon,Z.Hu,D.Chebotarov, S.Tai,Z.Wu, ..., J.Li, et al. Genomic variation in 3,010 diverse accessions of Asian cultivated rice. Nature. 557(7703),43-49, 2018. B.Wang, J.Li, X.Cheng, Q.Zhou, J.Yang, M.Zhang, H.Chen, J.Li*. NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis. Scientific Reports. 8:6021, 2018. J.Xiao,A.Tanca, B.Jia, R.Yang, B.Wang,Y.Zhang J.Li*. Metagenomic Taxonomy-Guided Database-Searching Strategy for Improving Metaproteomic Analysis. Journal of Proteome Research. 6;17(4):1596-1605, 2018. M.Lei, J.Xu, LC.Huang, L.Wang, J.Li*. Network module-based model in the differential expression analysis for RNA-seq. Bioinformatics. 33(17):2699-2705, 2017. M.Zhang, B.Wang, J.Xu, X.Wang, L.Xie, B.Zhang*, Y.Li*, J.Li*. CanProVar 2.0: An Updated Database of Human Cancer Proteome Variation. Journal of Proteome Research. 16(2):421-432, 2017. M.Zhang, H.Li, Y.He, H.Sun, L.Xia, L.Wang, B.Sun, L.Ma, G.Zhang, J.Li*, Y.Li*, L.Xie*. Construction and Deciphering of Human Phosphorylation-Mediated Signaling Transduction Networks. Journal of Proteome Research 14(7):2745-57, 2015. J. Xu, L. Wang, J. Li*. Biological network module-based model for the analysis of differential expression in shotgun proteomics. Journal of Proteome Research. 13 (12): 5743-50, 2014. Q. Wang, S. Zhang, S. Pang, M. Zhang, B. Wang, Q. Liu*,J. Li*. GroupRank: Rank Candidate Genes in PPI Network by Differentially Expressed Gene Groups. PLoS One. 9(10): e110406, 2014. J Wang, D. Zhang, J. Li*. PREAL: Prediction of Allergenic Protein By Maximum Relevance Minimum Redundancy (MRMR) Feature Selection. BMC Systems Biology. 7(Suppl 5):S9, 2013. J Wang, Y Yu, Y Zhao, D. Zhang and J. Li*. Evaluation and Integration of Existing Methods for Computational Prediction of Allergens. BMC Bioinformatics. 14(Suppl 4): S1, 2013. Y. He, M. Zhang, Y. Ju, D. Lv, Z. Yu, H. Sun, W. Yuan, F.He, J. Zhang, H. Li, J. Li, Y.Li, G. Zhang , L. Xie . dbDEPC 2.0: database of differentially expressed proteins in human cancers. Nucleic Acids Research, 40(Database issue): D964-71, 2012. J. Li, D. Dexter, B. Zhang. CanProVar: A Human Cancer Proteome Variation Database. Human Mutation. 31(3):219-28, 2010. D. Lin, J. Li, R.J. Slebos, D.C. Liebler. Cysteinyl Peptide Capture for Shotgun Proteomics: Global Assessment of Chemoselective Fractionation. Journal of Proteome Research. 9(10):5461-72, 2010. J. Li, L. L. Zimmerman, B.-H. Park, D.L. Tabb, D.C. Liebler, B. Zhang. Network-assisted Protein Identification and Data Interpretation in Shotgun Proteomics. Molecular Systems Biology. 5: 303, 2009. T.A.Addona, … J. Li, …S.A. Carr. Multi-Site Assessment of The Precision and Reproducibility of Multiple Reaction Monitoring–based Measurements of Proteins in Plasma. Nature Biotechnology.27, 633-641, 2009. H.L Ball, B. Zhang, J. Riches, R. Gandhi, J. Li, J. M. Rommens, J.S. Myers. SBDS Is A Multi-functional Protein Implicated in Cellular Stress Responses. Human Molecular Genetics. 18(19): 3684-95, 2009. J. Li, Z. Liu, Y. Pan, Q. Liu, X. Fu, N.GF. Cooper, Y. Li, M. Qiu, T. Shi. Regulatory Module Network of bHLH Transcription Factors in Mouse Brain. Genome Biology. 8: R244, 2007.