个人简介
上海交通大学研究员,博导,Bio-X研究院院长助理。2002年获中国医科大学博士学位。上海市科技启明星,上海医学会医学遗传学分会秘书。主持的973子课题已通过验收并评为“优”,主持一项国家自然基金项目、负责一项国际合作课题。参编专著、译著四部,发表SCI论文40多篇,第一作者和通讯作者论文他引次数超过160次。
研究领域
精神疾病易感基因的研究,破解精神分裂症患者结直肠癌发生率低于正常之谜的初步研究,出生前营养不良导致精神分裂症的分子机制初探,揭示出生前营养不良导致成年后精神疾病发病风险增加的分子机制。
近期论文
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Wang Y, Zhang J, Liu B, Shao L, Wei Z, Li X, Ji J, Yang F, Wang T, Liu J, Wan C, Li B, Xu Y, Feng G, He L*, He G*. Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population. World J Biol Psychiatry. 2010;11(8):956-63. HTR2C promoter polymorphisms are associated with risperidone efficacy in Chinese female patients.Liu BC, Zhang J, Wang L, Li XW, Wang Y, Wei ZY, Ji J, Yang FP, Wan CL, Xu YF, Feng GY, He L*, He G*. Pharmacogenomics. 2010;11(5):685-92. Shi YY*, He G*, Zhang Z, Tang W, Zhang J Jr, Zhao Q, Zhang J Sr, Li XW, Xi ZR, Fang C, Zhao XZ, Feng GY, He L*. A study of rare structural variants in schizophrenia patients and normal controls from Chinese Han population. Mol Psychiatry. 2008 Oct;13(10):911-3. Zhang J, Shen Y, He G*, Li X, Meng J, Guo S, Li H, Gu N, Feng G, He L*. Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32(2): 467-71. He G#, Liu X#, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L*. MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese. Mol Psychiatry. 2006; 11(8):748-51. Chen Q, He G, Qin W, Chen QY, Zhao XZ, Duan SW, Liu XM, Feng GY, Xu YF, St Clair D, Li M, Wang JH, Xing YL, Shi JG, He L*. Family-based association study of synapsin II and schizophrenia. Am J Hum Genet. 2004; 75(5):873-7.