个人简介
学历和研究经历：毕业于浙江医科大学生物医学工程系，毕业后分配到浙江医科大学分子生物学实验室工作，2002 年成立神经生物学教研室后转入神经生物学教研室从事教学和科研工作，同年以同等学力考上博士研究生，2005年6月毕业，获博士学位。2003年3月至2005年4月公派赴美国City of Hope National Medical Center从事访问学者研究工作，2006年11月至2007年2月赴香港科技大学生物化学系从事合作研究。主要研究方向为离子型谷氨酸受体及其亚单位在中枢神经系统生理及病理过程中的作用。
近期论文
查看导师最新文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
（1） Lijun Zhu, Bingsen Zhou, Xinhuan Chen et al. Inhibitory mechanisms of heterocyclic carboxaldehyde thiosemicabazones for two forms of human ribonucleotide reductase. Biochemical Pharmacology 2009;78:1178-1185.
（2） Shao Xin*, Lijun Zhu*, Yubin Wang et al. Threonine 82 at the PDZ Domain of PICK1 is Critical for AMPA Receptor Interaction and Localization, Neurochemistry International (accepted) (* co-first author)
（3） Yi Shen, ShuangShuang Liu, MinYe Zhan, Jianhong Luo, Lijun Zhu. Interleukin-2 enhances dendritic development and spinogenesis in cultured hippocampal neurons. Anatomical Record (accepted) .
（4） Yi Shen*, Li-Jun Zhu*, Shuang-Shuang Liu, Su-Ya Zhou and Jian-Hong Luo. Interleukin-2 inhibits NMDA receptor-mediated currents directly and may differentially affect subtypes. Biochem Biophys Res Commun. 2006 Dec 15;351(2):449-54. (* co-first author)
（5） Min Guan, Lijun Zhu, George Somlo, et al. Bortezomib therapeutic effect is associated with expression of FGFR3 in multiple myeloma cells. Anticancer Res. 2009 Jan;29(1):1-9.
（6） Lijun Zhu, George Somlo, Bingsen Zhou, et al. Fibroblast Growth Factor Receptor 3 inhibited by short-hairpin RNAs Leads to Apoptosis in Multiple Myeloma. Molecular Cancer Therapeutics 2005 May;4(5):787-98
（7） Lijun Zhu, Yun Yen, Jimin Shao, et al.Fibroblast Growth Factor Receptor 3 Up-regulates Vascular Endothelial Growth Factor Expression In L6 Cells. International Journal of pharmacology 2(3): 324-330, 2006 .
（8） Zhu Lijun, Chen Z, Zhang LS, Xu SJ, Xu AJ, Luo JH. Spatiotemporal changes of the N-methyl-D-aspartate receptor subunit levels in rats with pentylenetetrazole-induced seizures. Neurosci Lett. 2004 Feb 6;356(1):53-6.
（9） Jimin Shao, Bingsen Zhou, Lijun Zhu, Weihua Qiu, Yate-Ching Yuan, Bixin Xi, and Yun Yen. In vitro characterization of enzymatic properties and inhibition of the p53R2 subunit of human ribonucleotide reductase. Cancer Research 2004; 64: 1-6.
（10） Jimin Shao, Bingsen Zhou, Lijun Zhu, Angel J. Di Bilio, Leila Su, Yate-Ching Yuan, Shijun Ren, Eric J. Lien, Jennifer Shih, and Yun Yen. Determination of the potency and subunit-selectivity of ribonucleotide reductase inhibitors with a recombinant-holoenzyme-based in vitro assay. Biochemical Pharmacology 2005; 69: 627–634.
（11） Shao J, Zhou B, Di Bilio AJ, Zhu Lijun, Wang T, Qi C, Shih J, Yen Y. A Ferrous-Triapine complex mediates formation of reactive oxygen species that inactivate human ribonucleotide reductase.Mol Cancer Ther. 2006 Mar;5(3):586-92.
（12） Chung V, Zhou B, Liu X, Zhu Lijun, Boo LM, Nguyen HV, Ann DK, Song J, Chen Y, Yen Y. SUMOylation plays a role in gemcitabine- and bortezomib-induced cytotoxicity in human oropharyngeal carcinoma KB gemcitabine-resistant clone. Mol Cancer Ther. 2006 Mar;5(3):533-40.
（13） Xu SJ, Chen Z, Zhu Lijun, Shen HQ, Luo JH. Visual recognition memory is related to basic expression level of NMDA receptor NR1/NR2B subtype in hippocampus and striatum of rats. Acta Pharmacol Sin. 2005 Feb;26(2):177-80.
（14） Chen zhong, Li Weidong, Zhu Lijun, Shen YingJie, Wei Erqing. Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats Acta pharmacol Sin 2002;23(4) 361-366.
京公网安备 11010802027423号