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个人简介

周天华,博士,浙江大学求是特聘教授,“国家杰出青年科研基金”获得者,教育部“新世纪优秀人才计划”获得者、科技部“中青年科技创新领军人才”,浙江省“钱江人才计划”获得者,浙江省重点科技创新团队(胃肠疾病诊治新技术创新团队)首席科学家;兼任中国细胞生物学学会理事、中国细胞生物学学会青年委员会副主任委员、细胞结构与细胞行为分会副会长、浙江大学青年教授联谊会副会长、Cell Research(影响因子14.8)、Journal of Experimental Clinical Cancer Research(影响因子4.8)等期刊编委。1988年起就读于浙江大学医学院,1993年获医学学士学位,1996年获临床医学硕士学位,1999年毕业于中科院上海生命科学研究院获博士学位。2000年至2006年在美国哈佛大学分子细胞生物学系进行博士后训练。现任浙江大学学位评定委员会办公室主任、学科建设处处长、医学院细胞生物学与遗传学系主任、分子医学研究中心主任、医学细胞生物学主讲教师(http://mypage.zju.edu.cn/0005005)。

研究领域

分子细胞生物学、胃肠肿瘤学

近期论文

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1. Shen M, Cai Y, Yang Y, Yan X, Liu X and Zhou T*. (2013). Centrosomal Protein FOR20 is essential for S-phase progression by Recruiting Plk1 to Centrosomes. Cell Research 23(11):1284-1295. doi:10.1038/cr.2013.127(最新影响因子: 10.526)published online 10 September 2013. 2. Deng Y, Huang Z, Xu Y, Jin J, Zhuo W, Zhang C, Zhang X, Shen M, Yan X, Wang L, Wang X, Kang Y, Si J* and Zhou T*. (2013). MiR-215 modulates gastric cancer cell proliferation by targeting RB1. Cancer Letters Aug 24. doi: 10.1016/j.canlet.2013.08.033. (最新影响因子: 4.23). 3. Liu Y, Yan X and Zhou T*. (2013). TBCK Influences Cell Proliferation, Cell Size and mTOR Signaling Pathway. PLOS ONE 8(8): e71349. doi:10.1371/journal.pone.0071349 (最新影响因子3.73). 4. Xu Y, Deng Y, Yan X and Zhou T*. (2011). Targeting miR-375 in gastric cancer. Expert Opinion on Therapeutic Targets 15(8):961-972.(当年影响因子: 3.716) 5. Zhu X, Liu X, Jin Q, Cai Y, Yang Y and Zhou T*. (2010). The L279P Mutation of Nuclear Distribution Gene C (NudC) Influences Its Chaperone Activity and LIS1 Stability. Journal of Biological Chemistry 285(39):29903-29910. (当年影响因子: 5. 328) 6. Ding L, Xu Y, Zhang W, Deng Y, Si M, Du Y, Hao H, Liu X, Si J* and Zhou T*. (2010). MiR-375 Frequently Down-regulated in Gastric Cancer Inhibits Cell Proliferation by Targeting JAK2. Cell Research 20(7):784-793. (当年影响因子: 9.417) 7. Yang Y, Yan X, Cai Y, Lu Y, Si J and Zhou T*. (2010). NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. Proceedings of the National Academy of Sciences of the United States of America 107(8): 3499-3504.(当年影响因子: 9.771) 8. Cai Y, Yang Y, Shen M and Zhou T*. (2009) Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody. Cell Research 19(11):1305-1308. (当年影响因子: 8.151) 9. Du Y, Xu Y, Ding L, Yao H, Yu H, Zhou T* and Si M*. (2009) Down-regulation of miR-141 in gastric cancer and its involvement in cell growth. Journal of Gastroenterology 44(6):556–561. (当年影响因子: 2.909) 10. Zhou T, Zimmerman W, Liu X and Erikson RL. (2006). A Mammalian NudC-Like Protein Essential for Dynein Stability and Cell Viability. Proceedings of the National Academy of Sciences of the United States of America 103(24):9039-9044. (当年影响因子: 9.643) 11. Zhou T,* Aumais J, Liu X, Yu-Lee, LY and Erikson, RL. (2003). A role for Plk1 phosphorylation of NudC in cytokinesis. Developmental Cell 5(1):127-138. (当年影响因子: 14.807) 12. Zhou TH, Ling K, Guo J, Zhou H, Wu Y, Jing Q, Ma L and Pei G. (2000). Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. Journal of Biological Chemistry 275(4):2513-2519. (当年影响因子: 7.368)) 13. Wu GX,# Lin YM, # Zhou TH, # Gao H and Pei G. (2000). Significant down-regulation of alpha-albumin in human hepatoma and its implication. Cancer Letters 160(2), 229-236. (#共同第1作者,当年影响因子: 1.517) 14. Zhou TH, Ren XH, Yin DL, Wu YL, Li M, Lu CZ, Wu DC, Wu YQ, Peng YQ, Wang YP, Ma L and Pei G. (1997). Retardation of pain development: a case of recovery from congenital insensitivity to pain. Acta Anaesthesiologica Scandinavica 41, 1077-1079. (当年影响因子: 1.953)

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