个人简介
2008年毕业于英国伦敦大学国王学院心血管系并获博士学位（PhD）。现任浙江大学医学院附属第一医院心内科副主任医师、副研究员，博士生导师。兼任中华医学会心血管病分会青年委员、基础研究学组委员；中国病理生理学会心血管专业委员会青年委员，国际心脏病研究会（ISHR）中国分会执委会青年委员；浙江省生物医学学会理事；浙江省生物医学工程学会心脏专业委员会委员兼秘书；《中国医学前沿杂志》编委。学习经历 1994.9-1999.6：浙江大学医学院临床医学系，99年6月获学士学位 1999.9-2002.6：浙江大学医学院内科心血管病专业，02年6月获硕士学位 2005.9-2008.12: 英国伦敦大学国王学院心血管系，08年12月获博士学位 研究工作经历 2002.8-2005.9：浙江大学医学院附属第一医院心内科，2004年9月晋升主治医师 2008.9-2008.12：英国伦敦大学国王学院血管生物学研究所 研究助理 2009.1-至今：浙江大学医学院附属第一医院心内科，同时也是浙江大学心血管病研究所成员 2009.12：晋升浙江大学医学部副研究员 2010.7：浙江大学医学部硕士生导师 2011.7：浙江大学医学部博士生导师 2013.12：浙江大学医学院附属第一医院副主任医师；科室副主任 2015.10：浙江大学医学部 教授
研究领域
动脉粥样硬化发病机制、血管干细胞生物学及血管组织工程
近期论文
查看导师新发文章
（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）
1. Chen T1, Margariti A, Kelaini S, Cochrane A, Guha ST, Hu Y, Stitt AW, Zhang L*, Xu* Q MicroRNA199b Modulates Vascular Cell Fate during iPS Cell Differentiation by Targeting the Notch Ligand Jagged1 and Enhancing VEGF Signaling. Stem Cells. 2014 Dec 23. doi: 10.1002/stem. (*corresponding author) (影响因子7.133，TOP期刊)
2. Yu X*, Zhang L*, Wen G, Zhao H3, Luong LA3, Chen Q4, Huang Y4, Zhu J2, Ye S3, Xu Q5, Wang W6, Xiao Q3.Upregulated sirtuin 1 by miRNA-34a is required for smooth muscle cell differentiation from pluripotent stem cells. Cell Death Differ. 2014 Dec 19. doi: 10.1038/cdd.2014.206.（co-first author，非第一单位）(影响因子8.835，TOP期刊)
3. Zhao H1, Wen G1, Huang Y1, Yu X1, Chen Q1, Afzal TA1, Luong le A1, Zhu J1, Shu Y1, Zhang L*, Xiao Q*.MicroRNA-22 Regulates Smooth Muscle Cell Differentiation From Stem Cells by Targeting Methyl CpG–Binding Protein 2. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):918-29. doi: 10.1161/ATVBAHA.114.305212. (*corresponding author，非第一单位) （影响因子7.804，TOP期刊)
4. Zhou Y1, Yang F, Chen T, Wu Y, Yang M, Zhu J, Zhang L. An updated view on the differentiation of stem cells into endothelial cells. Sci China Life Sci. 2014 Aug;57(8):763-73. doi: 10.1007/s11427-014-4712-4. Epub 2014 Aug 8.（IF 1.512）
5. Li Zhang, Qingbo Xu. Stem/Progenitor cells in vascular regeneration.Arteriosclerosis, Thrombosis, and Vascular Biology (影响因子7.804，TOP期刊) 2014 Jun;34(6):1114-9. doi: 10.1161/ATVBAHA.114.303809.
6. Yijiang Zhou, Feng Yang, Yutao Wu, Mei Yang, Qingzhong Xiao*, Li Zhang*. MicroRNAs in Endothelial Development and Differentiation. Journal of Stem Cell Research & Therapy (IF 5.86) 2014 accepted. (*corresponding author)
7. Jian Chen, Lei Zhao, Zhelan Zheng, Yijiang Zhou, Li Zhang*, Guoping Jiang. Retrospective Echocardiographical Analysis of Unilateral Absence of Pulmonary Artery. Hong Kong Journal of Paediatrics 2014; 19:10-14. (*corresponding author)
8. Qishan Chen, Min Jin, Jianhua Zhu, Qingzhong Xiao, Li Zhang*. Functions of heterogeneous nuclear ribonucleoproteins (hnRNPs) in stem cell maintenance and differentiation. BioMed Research International (IF 2.804) 2013: 623978. doi: 10.1155/2013/623978. (*corresponding author)
9. Qishan Chen, Min Jin, Feng Yang, Jianhua Zhu, Qingzhong Xiao, Li Zhang*. Matrix metalloproteinases: regulators of cell behavior in vascular formation and remodeling. Mediators of Inflammation (IF 3.263) Volume 2013 (2013), Article ID 928315, http://dx.doi.org/10.1155/2013/928315 (*corresponding author)
10. Gao D, Zhang L, Dhillon R, Hong TT, Shaw RM, Zhu J. Dynasore protects mitochondria and improves cardiac lusitropy in langendorff perfused mouse heart. PLoS One（IF 4.65）2013 Apr 15;8(4):e60967. doi: 10.1371/journal.pone.0060967.
11. Fang C, Wen G, Zhang L, Lin L, Moore A, Wu S, Ye S, Xiao Q*. An Important Role of Matrix Metalloproteinase-8 in Angiogenesis in Vitro and in Vivo. Cardiovascular Research（IF 6.064，TOP期刊）2013 Mar 19. [Epub ahead of print]
12. Yuan Huang, Luyang Lin, Xiaotian Yu, Guanmei Wen, Xiangyuan Pu, Hanqing Zhao, Changcun Fang, Jianhua Zhu, Qingbo Xu, Shu Ye, Li Zhang*, Qingzhong Xiao*. Functional Involvements of Heterogeneous Nuclear Ribonucleoprotein A1 in Smooth Muscle Differentiation from Stem Cells in vitro and in vivo. Stem Cells（IF 7.781，TOP期刊）2013 Jan 17 (*corresponding author)
13. Xiaoye Zheng, Chao Shen, Liangfeng Zhu, Qi Shan Chen, Yutao Wu, Hui Yan, Ting Chen, Qingzhong Xiao, Jianhua Zhu*, Li Zhang*. Angiotensin II promotes differentiation of mouse embryonic stem cells to vascular smooth muscle cells through PI3-kinase signaling pathway and NF-κB. Differentiation（IF 3.069）. 2013 85:41-54 (*corresponding author)
14. Yijiang Zhou, Jianhua Zhu, Qingzhong Xiao*, Li Zhang*. Reactive oxygen species in vascular formation and development. Oxidative Medicine and Cellular Longevity (IF 3.393). 2013:374963. doi: 10.1155/2013/374963. Epub 2013 Jan 22 (*corresponding author)
15. Jianhua Zhu; Chen Ting; Lin Yan; Zhoubin Li; Meimei Wong; Xiaoye Zheng; Xiaopin Pan; Li Zhang*, Hui Yan. Regulation of microRNA-155 in atherosclerotic inflammatory responses by targeting MAP3K10. PloS ONE（IF 4.092） 2012 November; 7(11):e46551 (*corresponding author)
16. Li Zhang, Yijiang Zhou, Jianhua Zhu, Qingbo Xu. An updated view on stem cell differentiation into smooth muscle cells. Vascular pharmacology（IF 2.63）2012 May-Jun;56(5-6):280-7.
17. Zhang L, Jin M, Margariti A, Wang G, Luo Z, Zampetaki A, Zeng L, Ye S, Zhu J, Xiao Q. Sp1-dependent activation of HDAC7 is required for PDGF-BB-induced smooth muscle cell differentiation from stem cells. J Biol Chem（IF 5.328 ，TOP期刊）. 2010 Dec 3; 285(49):38463-72.
18. Zhang L, Sheppard OR, Shah AM, Brewer AC. Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F. Free Radic Biol Med（IF 5.399，TOP期刊）. 2008 Sep 1;45(5):679-85.
京公网安备 11010802027423号