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个人简介

博士,1982年毕业于武汉大学生物系生物化学专业,先后在美国、日本、香港进行合作研究及做博士后。1985-1999年在中国科学院水生生物研究所从事生态毒理学的研究工作。1999年8月作为人才引进到浙江大学从事环境毒理学和生化毒理学研究工作, 2009年入选浙江省151人才工程计划重点资助人员。 中国环境诱变剂学会理事,《癌变.畸变.突变》杂志编委,浙江省生化学会理事。已发表论文120余篇,获浙江省科技进步二等奖、三等奖各一项,授权发明专利6项。

研究领域

1.蛋白磷酸酶2A在微囊藻毒素致毒过程中的作用。 2.蛋白磷酸酶2A与疾病相关性研究。 3.环境污染物引起的细胞信号转导网络的改变及其细胞学效应。 4.噬藻体控制水华蓝藻的基本方法与技术。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1.Fu Wenyu, Chen Jiaping, Wang Xiumin and Xu Lihong. Altered expression of p53, Bcl-2 and Bax induced by microcystin-LR in vivo and in vitro, Toxicon,2005,46: 171-177 2.Fu Wenyu, Xu Lihong, Yu Yingnian. Proteomic analysis of cellular response to microcystin in human amnion FL cells, Journal of Proteome Research, 2005,4,2207-2215 3.Liu Huigang, Wang Yan, Lian Lingjun and Xu Lihong. Tributytin induces DNA damage as well as oxidative damage in rats, Environmental Toxicology,2006,21,166-171 4.Jin XU, Lin-dan JI, Li-hong XU. Lead-induced apoptosis in PC 12 cells: involvement of p53, Bcl-2 family and caspase-3. Toxicology Letters,2006,166:160-167 5.Xiao-Feng Wang, Ming-Luan Xing, Ying Shen, Xin Zhu, Li-Hong Xu. Oral administration of Cr(VI) induced oxidative stress, DNA damage and apoptotic cell death in mice,Toxicology,2006,228:12-23 6.Zhu Xin, Mingluan Xing, Jianlin Lou, Xiaofeng Wang, Wenyu Fu, XU Lihong Apoptotic related biochemical changes in human amnion cells induced by tributyltin,Toxicology,2007,230:45-52 7.Liu Huigang, Li-Hong Xu. Garlic oil prevents tributyltin-induced oxidative damage in vivo and in vitro. Journal of Food Protection. 2007,70(3):716-721 8.Liu Huigang, Guo Zonglou,Lihong Xu and Stephen Hsu. Protective effect of green tea polyphenols on tributyltin-induced oxidative damage detected by in vivo and in vitro models,Environmental Toxicology ,2008,23(1):77-83 9.Xing Mingluan,Wang Xiaofeng, Lihong Xu. Alteration of proteins expression in apoptotic FL cells induced by MCLR,Environmental Toxicology 23(4): 451-8 10.Jin Xu, Ling-jun Lian, Chen Wu, Xiao-feng Wang, Wen-yu Fu, Li-hong Xu Lead induces oxidative stress, DNA damage and alteration of p53,Bax and Bcl-2 expressions in mice. Food and Chemical Toxicology,2008,46(5): 1488-1494 11.Huang Pu,Xu Lihong,Oral administration of cyanobacterial bloom extract induced the altered expression of the PP2A, Bax and Bcl-2 in mice,Environmental Toxicology,2008, 23(6):688-693 12.Wenyu Fu,Yu Yingnian,Xu Lihong. Identification of temporal differentially expressed protein responses to microcystin in human amniotic epithelial cells,Chemical Research in Toxicology,2009,22(1):41-51 13.Ming-luan Xing, Xiao-feng Wang, Xin Zhu, Xu-dong Zhou, Li-hong Xu,Morphological and Biochemical Changes Associated with Apoptosis Induced by Okadaic Acid in Human Amniotic FL Cells Environmental Toxicology 24: 437–445, 2009 14.Xu Jin,Ji Lindan,Xu Lihong,Endoplasmic Reticulum May Not Be Involved in the Lead-Induced Apoptosis in PC 12 Cells In Vitro,Environmental Toxicology,2010,25: 55–60 15.Xiao-Feng Wang, Xiao-Ming Lou, Ying Shen, Ming-Luan Xing, Li-Hong Xu. Apoptotic-related protein changes induced by hexavalent chromium in mice liver. Environmental Toxicology 2010,25: 77–82 16.Huang Pu, Qun Zheng and Lihong Xu, The apoptotic effect of oral administration of microcystin-RR on mice liver. Environmental Toxicology, 2010.

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