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个人简介

学历和研究经历: 2001.12-2004.6 德国基尔大学医学院免疫学研究所 博士 1998.8-2001.6 浙江大学医学院 医学微生物学/病毒学 硕士 1991.8-1996.6 浙江医科大学临床医学系 学士 2008.8-2010.6 UCIrvine Associate Specilist 2006.12- 浙江大学医学院病原生物学教研室 副教授 2005.7-2005.9 德国基尔大学医学院免疫学研究所 访问学者(DAAD资助) 2004.8-2006.12 浙江大学医学院病原生物学教研室 讲师 1996.8-2001.12 浙江大学医学院微生物学教研室 助教

研究领域

病毒感染与免疫调控及相关信号传导

近期论文

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Galitovskiy V*, Qian J*, Chernyavsky AI, Marchenko S, Gindi V, Edwards RA, Grando SA. Cytokine-Induced Alterations of {alpha}7 Nicotinic Receptor in Colonic CD4 T Cells Mediate Dichotomous Response to Nicotine in Murine Models of Th1/Th17- versus Th2-Mediated Colitis. J Immunol. 2011 Sep 1;187(5):2677-87. (equally contributed) Qian J, Galitovskiy V, Chernyavsky AI, Marchenko S, Grando SA. Plasticity of the murine spleen T-cell cholinergic receptors and their role in in vitro differentiation of naïve CD4 T cells toward the Th1, Th2 and Th17 lineages. Genes Immun. 2011 Apr;12(3):222-30 Koval L, Lykhmus O, Zhmak M, Khruschov A, Tsetlin V, Magrini E, Viola A, Chernyavsky A, Qian J, Grando S, Komisarenko S, Skok M. Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro. Int J Biochem Cell Biol. 2011 Apr; 43(4):516-24. Chernyavsky AI, Arredondo J, Galitovskiy V, Qian J, Grando SA. Upregulation of nuclear factor-kappaB expression by SLURP-1 is mediated by alpha7-nicotinic acetylcholine receptor and involves both ionic events and activation of protein kinases. Am J Physiol Cell Physiol. 2010 Nov;299(5):C903-11. Epub 2010 Jul 21. 余蓓蓓,胡勇,彭慧琴,严杰,钱景(通讯作者)。 呼吸道合胞病毒G蛋白基因重组质粒诱导小鼠免疫保护性及机制研究。 中华微生物学和免疫学杂志 2010 30(3), 218-223 余蓓蓓,冯燕,徐昌平,卢亦愚,钱景(通讯作者)。含内质控多重荧光RT-PCR同时检测麻疹病毒和风疹病毒的研究。 病毒学报 2010 26(2), 109-114 Chernyavsky A, Arredondo J, Galitovskiy V, Qian J and Grando SA. Structure and function of the nicotinic arm of acetylcholine regulatory axis in human leukemic T cells. Int J Immunopathol Pharmacol. 2009; 22(2): 461-472 Chernyavsky AI, Arredondo J, Qian J, Galitovskiy V, Grando SA. Coupling of ionic events to protein kinase signaling cascades upon activation of alpha7 nicotinic receptor: cooperative regulation of alpha2-integrin expression and Rho kinase activity. J Biol Chem. 2009 Aug 14;284(33):22140-8. Epub 2009 Jun 23. Arredondo J, Omelchenko D, Chernyavsky AI, Qian J, Skok M, Grando SA. Functional role of the nicotinic arm of the acetylcholine regulatory axis in human B-cell lines. Journal of Experimental Pharmacology 2009:1 1–7

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