毛亚飞 - 浙江大学

个人简介

主要经历 2004-至今　浙江大学医学院副教授，硕导 1998-2004　浙江大学医学院　讲师 1993-1998　浙江医科大学　助教

研究领域

病原菌基因工程疫苗及相关药物研制　　主要研究幽门螺杆菌基因工程疫苗、金葡菌肠毒素相关药物研制。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Jie Yan, Li-Li Chen, Yi-Hui Luo, Ya-Fei Mao, Meng He. High frequency of HGV and TTV infections in blood donors in Hangzhou, WJG, 2001, 7(5): 637-641（SCI）4/5 2. Ya-Fei Mao, Jie Yan, Li-Wei Li, Li shu-ping. Construction of hpaA gene from a clinical isolate of Helicobacter pylori and identification of the fusion protein. WJG, 2003, 9(7):1529-1535（SCI）1/4 3. Jie Yan, Shao-Hui Liang, Ya-Fei Mao, Li-Wei Li, Shu-Ping Li. Construction of expression systems for flaA and flaB genes of Helicobacter pylori and determination of immunoreactivity and antigenicity of the recombinant proteins. WJG, 2003,9(10):2240-2250（SCI）3/5 4. Ya-Fei Mao, Jie Yan. Construction of prokaryotic expression system of ureB gene from a clinical Helicobacter pylori strain and identification of the recombinant protein immunity WJG, 2004, 10(7):977-984 5. Jie Yan, Ya-Fei Mao. Construction of prokaryotic expression system of vacA gene and detection of vacA gene, VacA protein and antibody in Helicobacter pylori isolates and patients’ sera WJG, 2004, 10 (7):985-990 6. Jie Yan, Ya-Fei Mao, Zhe-Xin Shao. Frequencies of the expression of main protein antigens from Helicobacter pylori isolates and production of specific serum antibodies in the infected patients. WJG，2005, 11(3):421-425 7. Ping Ruan, Xiao-Ping Xia, Dexter Sun, David M. Ojcius, Ya-Fei Mao, Wen-Yan Yue, Jie Yan (corresponding author). Recombinant SpaO and H1a as immunogens for protection of mice from lethal infection with Salmonella paratyphi A: Implications for rational design of typhoid fever vaccines. Vaccine, 2008, 26: 6639-6644 8. Luo DJ, Xue F, Ojcius DM, Zhao JF, Mao YF, Li LW, Lin XA, Yan J (corresponding author). Protein typing of major outer membrane lipoproteins from Chinese pathogenic Leptospira spp. and characterization of their immunogenicity. Vaccine, 2009, 28: 243-255. 9. Ai Hua Sun, Ya Fei Mao, Ye Hu, Qi Sun, Jie Yan (corresponding author). Sensitive and specific ELISA coated by TpN15-TpN17-TpN47 fusion protein for detection of antibodies to Treponema pallidum. Clin Chem Lab Med (CCLM), 2009, 47:321-326. 10. Dandan Jin, David M. Ojcius, Dexter Sun, Haiyan Dong, Yihui Luo, Yafei Mao, Jie Yan (corresponding author). Leptospira interrogans Induces Apoptosis in Macrophages via Caspase-8- and Caspase-3-Dependent Pathways. Infect Immun, 2009, 77: 799-809. 11. Haiyan Dong, Ye Hu, Feng Xue, Dexter Sun, David M. Ojcius, Yafei Mao, Jie Yan (corresponding author). Characterization of the ompL1 gene of pathogenic Leptospira species in China and cross-immunogenicity of the OmpL1 protein. BMC Microbiol, 2008, 8: 223-235. 12. Liu Y, Zheng W, Li L, Mao Y, Yan J (corresponding author). Pathogenesis of leptospirosis: interaction of Leptospira interrogans with in vitro cultured mammalian cells. J Med Microbiol Immunol, 2007, 196: 233-239 13. Lei Zhang, Chenglin Zhang, David M. Ojcius, Jinfang Zhao, Xu’ai Lin, Yafei Mao, Liwei Li, Jie Yan (corresponding author). Identification of Mce as a critical outer membrane protein of pathogenic Leptospira species responsible for RGD motif-dependent adherence and host-cell invasion. Mol Microbiol, 2010, In revision.(manuscritp No.: MMI-2010-09754)