个人简介
1998年毕业于浙江医科大学，2003年获浙江大学医学院生理学博士学位，2003年10至2006年10月在美国华盛顿大学医学院神经病理系从事帕金森病发病的分子机理的博士后研究工作，获得美国帕金森病基金会资助的博士后研究基金。2006年底回国，现在为浙江大学医学院神经生物学系副教授。目前主持国家自然科学基金和浙江省自然科学基金项目各1项，参与国家自然科学基金重点项目1项，并获得浙江大学优秀青年教师计划(紫金计划)资助。已发表SCI收录的论文近20篇，主要研究方向为帕金森病的发病机制以及生物标志物的研究。
近期论文
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1.Klegeris A, Li J, Bammler TK, Jin J, Zhu D, Kashima DT, Pan S, Hashioka S, Maguire J, McGeer PL, Zhang J. Prolyl endopeptidase is revealed following SILAC analysis to be a novel mediator of human microglial and THP-1 cell neurotoxicity. Glia. 2008, Apr 15;56(6):675-85.
2.Shi M*, Jin J*, Wang Y, et al.: Mortalin: A Protein Associated With Progression of Parkinson Disease? J Neuropathol Exp Neurol , 2008，67(2):117-24 (*：co-first author)
3.Pan S, Shi M, Jin J, Albin RL, Lieberman A, Gearing M, Lin B, Pan C, Yan X, Kashima DT et al: Proteomics identification of proteins in human cortex using multi-dimensional separations and MALDI tandem mass spectrometer. Mol Cell Proteomics 2007. Oct;6(10):1818-23
4.Leverenz JB, Umar I, Wang Q, Montine TJ, McMillan PJ, Tsuang DW, Jin J, Pan C, Shin J, Zhu D et al: Proteomic identification of novel proteins in cortical lewy bodies. Brain Pathol 2007, 17(2):139-145.
5.Jin J, Shie FS, Liu J, Wang Y, Davis J, Schantz AM, Montine KS, Montine TJ, Zhang J: Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein. J Neuroinflammation 2007, 4:2.
6.Jin J, Li GJ, Davis J, Zhu D, Wang Y, Pan C, Zhang J: Identification of novel proteins associated with both alpha-synuclein and DJ-1. Mol Cell Proteomics 2007, 6(5):845-859.
7.Jin J, Davis J, Zhu D, Kashima DT, Leroueil M, Pan C, Montine KS, Zhang J: Identification of novel proteins affected by rotenone in mitochondria of dopaminergic cells. BMC Neurosci 2007, 8(1):67.
8.Chen L, Jin J, Davis J, Zhou Y, Wang Y, Liu J, Lockhart PJ, Zhang J: Oligomeric alpha-synuclein inhibits tubulin polymerization. Biochem Biophys Res Commun 2007, 356(3):548-553.
9.Xu J, Chen J, Peskind ER, Jin J, Eng J, Pan C, Montine TJ, Goodlett DR, Zhang J: Characterization of proteome of human cerebrospinal fluid. Int Rev Neurobiol 2006, 73:29-98.
10.Pan S, Wang Y, Quinn JF, Peskind ER, Waichunas D, Wimberger JT, Jin J, Li JG, Zhu D, Pan C et al: Identification of glycoproteins in human cerebrospinal fluid with a complementary proteomic approach. J Proteome Res 2006, 5(10):2769-2779.
11.Jin J, Hulette C, Wang Y, Zhang T, Pan C, Wadhwa R, Zhang J: Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease. Mol Cell Proteomics 2006, 5(7):1193-1204.
12.Abdi F, Quinn JF, Jankovic J, McIntosh M, Leverenz JB, Peskind E, Nixon R, Nutt J, Chung K, Zabetian C, Jin J, et al: Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis 2006, 9(3):293-348.
13.Zhou Y, Wang Y, Kovacs M, Jin J, Zhang J: Microglial activation induced by neurodegeneration: a proteomic analysis. Mol Cell Proteomics 2005, 4(10):1471-1479.
14.Jin J, Meredith GE, Chen L, Zhou Y, Xu J, Shie FS, Lockhart P, Zhang J: Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson\'s disease. Brain Res Mol Brain Res 2005, 134(1):119-138.
15.Jin J, Yang J, Gao Z, Yu Y: Proteomic analysis of cellular responses to low concentration N-methyl-N\'-nitro-N-nitrosoguanidine in human amnion FL cells. Environ Mol Mutagen 2004, 43(2):93-99.
16.Gao Z, Jin J, Yang J, Yu Y: Zinc finger proteins and other transcription regulators as response proteins in benzo[a]pyrene exposed cells. Mutat Res 2004, 550(1-2):11-24.
17.金静华, 高志华, 杨军, 余应年. 低浓度MNNG诱发FL细胞应答反应的蛋白质组学研究. 浙江大学学报医学版,. 2003, 32(5):375-379.
18.Jin J, Gao Z, Guo L, Yang J, Yu Y: Altered expression of zinc finger proteins, ADAMs, and integrin-related proteins following treatment of cultured human cells with a low concentration of N-methyl-N\'-nitro-N-nitrosoguanidine. Environ Mol Mutagen 2003, 41(5):344-352.
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