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个人简介

教育: 1982年,浙江医科大学临床医学专业,医学学士 1989年,浙江医科大学妇产科专业,医学硕士 1997-1998年,美国Cincinnatti大学医学院妇产科系,生殖医学研究 工作经历: 1998年起先后担任浙江大学医学院妇产科医院副院长/浙江大学医学院科研副院长/浙江大学科学技术研究院副院长。2009年起担任浙江大学妇产科医院院长至今。 现为浙江大学求是特聘教授、澳大利亚Adelaide大学客座教授、“973”首席科学家、卫生部和浙江省有突出贡献中青年专家、教育部生殖遗传重点实验室主任、浙江省生殖中心主任、浙江大学妇产科和计划生育研究所所长。

研究领域

生殖内分泌

近期论文

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1.Ruan YC, Guo JH, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H*, Zhou WL*, Chan HC*: Activation of the epithelial Na(+) channel triggers prostaglandin E(2) release and production required for embryo implantation. Nat Med 2012 Jul;18(7):1112-7. (IF:22.462 ) 2.Zhang D, Tan YJ, Qu F, Sheng JZ, Huang HF*: Functions of water channels in male and female reproductive systems. Mol Aspects Med 2012,Oct-Dec; 33(5-6): 676-90.(IF:9.970 ) 3.Ding GL, Wang FF, Shu J, Tian S, Jiang Y, Zhang D, Wang N, Luo Q, Zhang Y, Jin F, Peter CK Leung, Sheng JZ*, Huang HF*: Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia. Diabetes 2012, 61:1133-1142. (IF:8.286) 4.Lu YC, Chen H, Fok KL, Tsang LL, Yu MK, Zhang XH, Chen J, Jiang X, Chung YW, Ma AC, Leung AY, Huang HF*, Chan HC*: CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Res. 2012 Oct;22(10):1453-1466.(IF:8.190) 5.Yin LJ, Zhang Y, Lv PP, He WH, Wu YT, Liu AX, Ding GL, Dong MY, Qu F, Xu CM, Zhu XM, Huang HF*: Insufficient maintenance DNA methylation is associated with abnormal embryonic development. BMC Med 2012 Mar 13;10:26. (IF:6.035 ) 6.Liu XM, Ding GL, Jiang Y, Pan HJ, Zhang D, Wang TT, Zhang RJ, Shu J, Sheng JZ, Huang H*. Down-Regulation of S100A11, a Calcium-Binding Protein, in Human Endometrium May Cause Reproductive Failure. J Clin Endocrinol Metab 2012 Oct; 97(10):3672-83. (IF:5.967 ) 7.Chen H, Guo JH, Lu YC, Ding GL, Yu MK, Tsang LL, Fok KL, Liu XM, Zhang XH, Chung YW, Huang P, Huang HF*, Chan HC*: Impaired CFTR-Dependent Amplification of FSH-Stimulated Estrogen Production in Cystic Fibrosis and PCOS. J Clin Endocrinol Metab 2012;97:923-32.(IF:5.967 ) 8.Zhang RJ, Zou LB, Zhang D, Tan YJ, Wang TT, Liu AX, Qu F, Meng Y, Ding GL, Lu YC, Lv PP, Sheng JZ*, Huang HF*: Functional Expression of Large-Conductance Calcium-Activated Potassium Channels in Human Endometrium: A Novel Mechanism Involved in Endometrial Receptivity and Embryo Implantation. J Clin Endocrinol Metab 2012, 97:543-553.(IF:5.967 ) 9.Qu F, Wang FF, Yin R, Ding GL, El-Prince M, Gao Q, Shi BW, Pan HH, Huang YT, Jin M, Peter CK Leung, Sheng JZ, Huang HF*: A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells. J Mol Med (Berl) 2012 Aug; 90(8):911-23.(IF:4.668 ) 10.Lu YC, Ding GL, Yang J, Zhang YL, Shi S, Zhang RJ, Zhang D, Pan JX, Sheng JZ, Huang HF*: Small-conductance calcium-activated K+ channels 3 (SK3) regulate blastocyst hatching by control of intracellular calcium concentration. Hum Reprod 2012, 27:1421-1430(IF:4.475 ) 11.Zou LB, Zhang RJ, Tan YJ, Ding GL, Shi SA, Zhang D, He RH, Liu AX, Wang TT, Leung PCK, Sheng JZ*, Huang HF*: Identification of Estrogen Response Element in the Aquaporin-2 Gene That Mediates Estrogen-Induced Cell Migration and Invasion in Human Endometrial Carcinoma. J Clin Endocrinol Metab 2011, 96:E1399-E1408.(IF:5.967 ) 12.Liu AX, He WH, Yin LJ, Lv PP, Zhang Y, Sheng JZ, Leung PCK, Huang HF*: Sustained Endoplasmic Reticulum Stress as a Cofactor of Oxidative Stress in Decidual Cells from Patients with Early Pregnancy Loss. J Clin Endocrinol Metab 2011, 96:E493-E497.(IF:5.967 ) 13.Yu Zhang, Yan-Ling Zhang, Chun Feng, Yan-Ting Wu, Ai-Xia Liu, Jian-Zhong Sheng, Jie Cai, He-Feng Huang*. Comparative proteomic analysis of human placenta derived from assisted reproductive technology. Proteomics 2008, 8(20), 4344–4356. (IF:4.505 ) 14.Li MG, Ding GL, Chen XJ, Lu XP, Dong LJ, Dong MY, Yang XF Lu XE, Huang HF*. Association of Serum and Follicular Fluid Leptin Concentrations with Granulosa Cell Phosphorylated Signal Transducer and Activator of Transcription 3 Expression in Fertile Patients with Polycystic Ovarian Syndrome. J Clin Endocrinol Metab. 2007 Dec;92(12):4771-6. (IF:5.967 ) 15.Huang HF*, He RH, Sun CC, Zhang Y, Meng QX, Ma YY. Function of Aquaporins in Female & Male Reproductive Systems. Hum Reprod Update. 2006 Nov-Dec;12(6):785-95. (IF:9.234)

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