胡晓彤 - 浙江大学

个人简介

学习和工作简历 1980年9月-1986年7月杭州市学军中学 1986年9月-1991年7月浙江医科大学临床医学专业，攻读学士学位 1991年9月-1994年7月浙江医科大学组织胚胎学专业，攻读硕士学位 1995年8月-2000年9月浙江医科大学组织胚胎学教研室 2000年10月-至今浙江大学医学院附属邵逸夫医院生物医学研究（治疗）中心 2001年9月-2002年9月香港大学玛丽医院内科系进修 2002年12月-2006年12月香港大学医学院病理系，攻读博士学位 2010年3月-2010年4月香港大学医学院病理系访问学者

研究领域

肿瘤发生发展分子机制及早期诊断标志物研究

近期论文

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1.Fei W, Chen L, Chen J, Shi Q, Zhang L, Liu S, Li L, Zheng L, Hu X*. RBP4 and THBS2 are serum biomarkers for diagnosis of colorectal cancer. Oncotarget 2017 Sep 21; 8(54): 92254-64. (IF=5.415) 2.Liu S, Fei W, Shi Q, Li Q, Kuang Y, Wang C, He C, Hu X*. CHAC2, downregulated in gastric and colorectal cancers, Phospholipase C delta 1 is a novel 3p22.3 tumor suppressor involved in cytoskeleton organization, with its epigenetic silencing correlated with high-stage gastric cancer. ...Oncogene 2009 Jul; 3.Hu X*, Kuang Y, Li L, Tang H, Shi Q, Shu X, Zhang Y, Chan FK, Tao Q, He C. Epigenomic and Functional Characterization of Junctophilin 3 (JPH3) as a Novel Tumor Suppressor Being Frequently Inactivated by Promoter CpG Methylation in Digestive Cancers. Theranostics 2017 May 30; 7(7): 2150 -63. (IF=9.195) acted as a tumor suppressor inducing apoptosis and autophagy through unfolded protein response. Cell Death Dis 2017 Aug 24; 8(8): e3009. (IF=6.147) 28(26): 2466-75. (IF=8.559) 4.Liu X, Hu X, Kuang Y, Yan P, Li L, Li C, Tao Q, Cai X. BCLB, methylated in hepatocellular carcinoma, is a starvation stress sensor that induces apoptosis and autophagy through the AMPK-mTOR signaling cascade. Cancer Lett 2017 Jun 1; 395: 63-71. (IF=6.147) 5.Fei W, Liu S, Hu X*. High FOXRED1 expression predicted good prognosis of colorectal cancer. Am J Cancer Res 2016 Nov 1; 6(11): 2722-8. (IF=3.686) (IF=5.008) 6.Chen R, Zhu J, Dong Y, He C, Hu X*. Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells. Oncotarget 2015 Oct 20; 6(32): 32841-55. 7.Zhu J, Chen R, Mo L, Tang H, Kuang Y, Fei W, He C, Hu X*. Expression of fibulin-1 predicted good prognosis in patients with colorectal cancer. Am J Transl Res 2015 Feb 15; 7(2): 339-47. (IF=3.425) 8.Hu X, Xuan H, Du H, Jiang H, Huang J. Down-Regulation of CD9 by Methylation Decreased Bortezomib Sensitivity in Multiple Myeloma. PLoS One 2014 May 2; 9(5): e95765. (IF=3.532) 9.Hu X, Sui X, Li L, Huang X, Rong R, Su X, Shi Q, Mo L, Shu X, Kuang Y, Tao Q, He C. Protocadherin 17 acts as a tumor suppressor inducing tumor cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers. J Pathol 2013 Jan; 229(1): 62-73. (IF=7.33) 10.Sui XB, Jin LJ, Huang XF, Geng SM, He C, Hu XT*. p53 Signaling and Autophagy in Cancer: A 11.Hu XT, Chen YW, Liang ACT, Au WY, Wong KY, Wan TSK, Wong MLY, Shen L, Chan KK, Guo T, Chu KM, Tao Q, Chim CS, Loong F, Choi WWL, Lu L, So CC, Chan LC, Kwong YL, Liang RHS, Srivastava G.... CD44 activation in mature B-cell malignancies by a novel recurrent IGH translocation. Blood 2010 Mar;115(2): 2458-61. (IF=11.84) Revolutionized Strategy Could be Developed for Cancer Treatment. Autophagy 2011 Jun; 7(6): 565-71. (IF=11.019) 12.Hu XT, Zhang FB, Fan YC, Shu XS, Wong AH, Zhou W, Shi QL, Tang HM, Fu L, Guan XY, Rha SY, Tao Q, He C.