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个人简介

教育工作背景: 1996年7月 浙江医科大学 本科 2003年12月 瑞典卡罗琳斯卡研究院临床药理系 博士 2004-2005 年 比利时鲁汶大学分子血管中心 博士后 2005-2010 浙江大学医学院(人才引进) 副教授,副博士生导师 2011- 浙江大学医学院教授,博士生导师

研究领域

血小板基础研究

近期论文

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1. Hu H(胡虎), Daleskog M, Li N. Influences of fixatives on flow cytometric measurements of platelet P-selectin expression and fibrinogen binding. Thromb Res 2000; 100: 161-166.(影响因子2.01) 2. Li N, Hu H(胡虎), Linqvist M, Wikström Jonsson E, Goodall AH, Hjemdahl P. Platelet-leukocyte cross-talk in whole blood. Arterioscler Thromb Vasc Biol. 2000; 20: 2702-2708. (影响因子7.05) 3. Hu H(胡虎), Li N, Ekberg K, Johansson BL, Hjemdahl P. Insulin, but not proinsulin C-peptide, enhances platelet fibrinogen binding in vitro in Type 1 diabetes mellitus patients and healthy subjects. Thromb Res. 2002, 106:91-5. (影响因子2.01) 4. Hu H(胡虎), Hjemdahl P, Li N. Effects of insulin on platelet and leukocyte activity in whole blood. Thromb Res. 2002, 107:209-15. (影响因子2.01) 5. Hu H(胡虎), Zhang W, Li N. Glycoprotein IIb/IIIa inhibition attenuates platelet-activating factor-induced platelet activation by reducing protein kinase C activity. J Thromb Haemost 2003, 2:1-8. (影响因子5.26) 6. Hu H(胡虎), Varon D, Hjemdahl P, Savion N, Schulman S, Li N. Platelet-leukocyte aggregation under shear stress: Differential involvement of selectins and integrins. Thromb Haemost 2003, 90: 679-87. (影响因子3.06) 7. Li N, Hu H(胡虎), Hjemdahl P. Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry. Thromb Res. 2003;111:165-70. (影响因子2.01) 8. Hu H(胡虎), Li N, Yngen M, Österson C-G, Wallen NH, Hjemdahl P. Enhanced leukocyte-platelet cross-talk in type 1 diabetes mellitus: relationship to microangiopathy. J Thromb Haemost. 2004, 2: 58-64. (影响因子5.26) 9. Yngen M, Ostenson CG, Hu H(胡虎), Li N, Hjemdahl P, Wallen NH. Enhanced P-selectin expression and increased soluble CD40 Ligand in patients with Type 1 diabetes mellitus and microangiopathy: evidence for platelet hyperactivity and chronic inflammation. Diabetologia. 2004, 47:537-40. (影响因子5.34) 10. Hu H(胡虎), Johansson B, Hjemdahl P, Li N. Exercise-induced platelet and leucocyte activation is not enhanced in well-controlled Type 1 diabetes, despite increased activity at rest. Diabetologia. 2004, 47:853-9. (影响因子5.34) 11. Perneby C, Wallen NH, Hu H(胡虎), Li N, Hjemdahl P. Prothrombotic responses to exercise are little influenced by clopidogrel treatment. Thromb Res. 2004, 114:235-43. (影响因子2.01) 12. Hu H(胡虎), Forslund M, Li N. Influence of extracellular calcium on single platelet activation as measured by whole blood flow cytometry. Thromb Res. 2005, 116:241-7. (影响因子2.01) 13. Oury C, Daenens K, Hu H(胡虎), Bryckaert M, Hoylaerts MF. ERK2 activation in arteriolar and venular murine thrombosis: role of platelet receptors GPIb and P2X1. J Thromb Haemost. 2006, 4(2):443-52. (影响因子5.26) 14.Dong Z, Hu H(胡虎),Chen W, Li z, Liu G, Yang J. Heat shock does not induce ΓH2AX foci formation but protects cells from N-methyl-N'-nitro-N-nitrosoguanidine induced genotoxicity. Mutation Research. 2007, 629:40-8. (影响因子2.18) 15. Razmara M, Hu H(胡虎), Masquelier M, Li N. Glycoprotein IIb/IIIa blockade inhibits platelet aminophospholipid exposure by potentiating translocase and attenuating scramblase activity. Cell Mol Life Sci. 2007,64:999-1008. (影响因子4.65) 16.Xu F, Wang F, Di M, Huang Q, Wang M, Hu H(胡虎), Jin Y, Dong J, Lai M. Classification based on the combination of molecular and pathologic predictors is superior to molecular classification on prognosis in colorectal carcinoma. Clin Cancer Res. 2007, 13:5082-8。(影响因子6.18) 17.Ruan W, Xu E, Xu F, Ma Y, Deng H, Huang Q, Lv B, Hu H(胡虎), Lin J, Cui J, Di M, Dong J, Lai M. IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis. Cancer Biol Ther. 2007,6:354-9. (影响因子2.71) 18.Ruan WJ, Lin J, Xu EP, Xu FY, Ma Y, Deng H, Huang Q, Lv BJ, Hu H(胡虎), Cui J, Di MJ, Dong JK, Lai MD. IGFBP7 plays a potential tumor suppressor role against colorectal carcinogenesis with its expression associated with DNA hypomethylation of exon 1. Zhejiang Univ Sci B. 2006,7:929-32.

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