韩卫东 - 浙江大学

个人简介

男，1979-10，肿瘤学博士，副研究员，硕士生导师。 2003.7获浙江大学医学院医学学士学位，同年进入浙江大学医学院肿瘤研究所学习，导师为教育部长江学者胡讯教授，2008.7年获肿瘤学博士学位，博士论文获全国优秀博士论文提名奖。2008-8进入浙江大学医学院附属邵逸夫医院肿瘤内科工作至今。2011.4至2012.10赴美国City of Hope Medical Center合作研究，

研究领域

自噬在肿瘤发生发展及抗肿瘤治疗过程中的作用。目前主持国家青年自然基金：一类necroptosis诱导剂抗肿瘤干细胞研究

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Han W, Li L, Qiu S, Lu Q, Pan Q, Gu Y, Luo J, Hu X. Shikonin circumvents cancer multidrug resisatnce by induction of necroptosis. Molecular Cancer Therapeutics. 2007;6(5);1641- 1649. 2. Li L, Han W*, Gu Y, Qiu S, Lu Q, Jin J, Luo J, Hu X. Honokiol induces a necrotic cell death through mitochondrial permeability transition pore. Cancer Research. 2007;67 (10);4894-4903. *共同第一作者。 3. Hu X, Han W, Li L. Targeting the Weak Point of Cancer by Induction of Necroptosis. Autophagy. 2007;3(5);490-492. 4. Zhang K, Han W*, Zhang R, Xu X, Pan Q, Hu X. Phenylobacterium zucineum sp. nov., a facultative intracellular bacterium isolated from a human erythroleukemia cell line K562. Systematic and applied microbiology. 2007;30(3);207-212. *共同第一作者。 5. Li L, Pan Q, Han W, Liu Z, Li L, Hu X. Schisandrin B Prevents Doxorubicin-induced Cardiotoxicity via Enhancing Glutathione Redox Cycling. Clinical Cancer Research. 2007; 13(22):6753-6760. 6. Han W, Xie J, LI L, Liu z, Hu X. Necrostatin-1 reverts shikonin-induced necroptosis to apoptosis. Apoptosis. 2009,May,01;14(5):674-86. 7．Han W, Pan H, Chen Y, Sun J, Wang Y, et al. EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells. PLoS ONE 2011 6(6): e18691. doi:10.1371/journal.pone.0018691. 8. Han W, Sun J, Feng L, Wang K, Li D, et al. Autophagy Inhibition Enhances Daunorubicin- Induced Apoptosis in K562 Cells. PLoS ONE 2011 6(12): e28491. doi:10.1371/journal. pone. 0028491. 9. Wang Y, Ding L, Wang X, Zhang J, Han W, Feng L, Sun J, Jin H, Wang XJ. Pterostilbene simultaneously induces apoptosis, cell cycle arrest and cyto-protective autophagy in breast cancer cells. Am J Transl Res. 2012;4(1):44-51. Epub 2012 Jan 5. 10．Han, W.; Xie, J.; Fang, Y.; Wang, Z.; Pan, H. Nec-1 Enhances Shikonin-Induced Apoptosis in Leukemia Cells by Inhibition of RIP-1 and ERK1/2. Int. J. Mol. Sci. 2012, 13, 7212-7225.