个人简介
心胸外科学博士,博士生导师,主任医师。浙江省心脏外科重点学科(创新学科)带头人,现任浙江大学医学院附属第二医院心脏大血管外科主任、心脏中心副主任;浙江省医学会心胸外科分会副主任委员。1998年7月和2002年7月先后获得浙江大学心胸外科学硕士和博士学位。2000年10月~2001年10月赴德国基尔大学学习并成为德国医师学会会员。在胸心外科疾病的诊断和手术治疗等方面积累了丰富的临床经验,尤其在小切口微创心内直视手术方面处于省内领先地位。主要研究方向为肺癌分子靶向治疗基础研究\心肌缺血再灌注损伤及冠脉搭桥血管移植物再狭窄的防治。发表论文30余篇,其中SCI收录论文15篇。作为项目负责人承担省部共建项目、浙江省自然科学基金、浙江省医药卫生科研基金等多项科研项目。先后获得浙江省科技进步二等奖、三等奖各一项。作为导师或导师组成员先后培养硕士、博士研究生十余名。
研究领域
肺癌分子靶向治疗基础研究\心肌缺血再灌注损伤及冠脉搭桥血管移植物再狭窄的防治等
近期论文
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[1].Kong M, Li X, Wang C, Ding C, Dong A, Duan Q, Shen Z Tissue distribution and cancer growth inhibition of magnetic lipoplex-delivered type 1 insulin-like growth factor receptor shRNA in nude mice. Acta Biochim Biophys Sin. 2012 ;44(7):591-6
[2].Ding C, Wang C, Dong A, Kong M, Jiang D, Tao K, Shen Z. Anterolateral minithoracotomy versus median sternotomy for the treatment of congenital heart defects: a meta-analysis and systematic review. J Cardiothorac Surg. 2012 May 4;7:43
[3].Chunmao Wang, Chao Ding, Minjian Kong, Ai-Qiang Dong, Jianfang Qian, Daming Jinag, Zhonghua,Shen. Tumor-targeting magnetic lipoplex delivery of short hairpin RNA suppresses IGF-1R overexpression of lung adenocarcinoma A549 cells in vitro and in vivo. Biochemical and Biophysical Research Communications. 2011, 410:537–42
[4].Wu M, Zhang S, Dong A, He Z, Chen S, Chen R. Long-term outcomes of maze procedure plus valve replacement in treating rheumatic valve disease resulting in atrial fibrillation. Ann Thorac Surg. 2010 Jun;89(6):1942-9.
[5].Minjian Kong, Junqiang Fan, Aiqiang Dong Hai-feng CHENG, and Rongzhen Xu. Effects of polyphyllin I on growth inhibition of human non-small lung cancer cells and in xenograft, Acta Biochim Biophys Sin 2010, 42: 827–833
[6].Zhao BQ, Dong AQ, Cai SY, Successful resection of a giant subpericardial lipoma with recurrent ventricular arrhythmias. Acta Cardiologica. 2009,64(2),275-277.
[7].Ai-Qiang Dong, Min-Jian Kong , Zhi-Yuan Ma, Jian-Fang QIAN , Hai-feng CHENG, and Xiao-hong XU Knock-down of the Insulin-like Growth Factor 1 Receptor Enhances the Chemosensitivity to Cisplatin in Human Lung Adenocarcinoma A549 Cells. Acta Biochimica et Biophysica Sinica 2008,40(6):497-504
[8].Ai-Qiang Dong, Min-Jian Kong, Zhi-Yuan Ma, Jian-Fang QIAN , and Xiao-hong XU. Down-regulation of IGF-ⅠR using small, interfering, hairpin RNA (siRNA) inhibits growth of human lung cancer cell line A549 in vitro and in nude mice. Cell Biology International. 2007,31(5):500-507.
[9].Ma Z, Dong A, Kong M, Qian F. Silencing of the type 1 insulin-like growth factor receptor increases the sensitivity to apoptosis and inhibits invasion in human lung adenocarcinoma A549 cells. Cellular and Molecular Biology Letters. 2007,12(4):556-72.
[10].Jian-Fang QIAN, Ai-Qiang DONG, Min-Jian KONG,Zhi-yuan MA, Jun-qiang FAN, and Guan-yu JIANG. Suppression of IGF-ⅠR Expression by Small Interfering RNA Inhibits A549 Human Lung Cancer Cell In Vitro Invasion and In Xenograft Nude Mice. Acta Biochimica et Biophysica Sinica. 2007,39(2):137-47.
[11].Ma Z, Dong A, Fan J, Cheng H. Does sleeve lobectomy concomitant with or without pulmonary artery reconstruction (double sleeve) have favorable results for non-small cell lung cancer compared with pneumonectomy? A meta-analysis. European Journal of Cardio-thoracic Surgery. 2007,32(1):20-28.
[12].Zhang S, Chen RK, Dong AQ, et al. Outcome of Cox Maze procedure concomitant with mitral valve operation in treatment of atrial fibrillation. Chin Med J (Engl). 2006,119(16)1392-1395.
[13].Zeng YJ, Xu SW, Wang Q, Chang Y, Dong AQ. Assessment of hemodynamics properties of a new-type artificial heart valve prosthesis using catheterization and echocardiography. Am J Hematol. 2006,81(8):563-7.