个人简介
B.Sc., University of Toronto (1994)
Ph.D., University of British Columbia (1999)
Awards & Recognition
- Japan Society for Promotion of Science - Invitation Fellowship (2010)
- Petro-CanadaYoung Investigator Award (2007)
- Elsevier Journal of Chromatography A Top Referee Award (2003, 2005)
- Premier's Research Excellence Award, Province of Ontario (2004-2009)
- CLL Teaching & Learning Grant, McMaster University (2004)
- Japan Society for Promotion of Science Postdoctoral Fellowship (2001-2003)
研究领域
Separation science, Metabolomics, Biomolecular interactions,
Capillary electrophoresis, Electrospray ionization,
Mass Spectrometry, Chemometrics, Chemical Education.
近期论文
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R. Lee and P. Britz-McKibbin "Differential Rates of Glutathione Oxidation for Assessment of Cellular Redox Status and Antioxidant Capacity by Capillary Electrophoresis-Mass Spectrometry: An Elusive Biomarker of Oxidative Stress" Anal. Chem. 81, 7047-7056, 2009.
K.R. Chalcraft, R. Lee, C. Mills and P. Britz-McKibbin "Virtual Quantification of Metabolites by Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry: Predicting Ionization Efficiency without Chemical Standards" Anal. Chem. 81, 2506-2515, 2009.
J.M.A. Gavina, M.T. Mazhab-Jafari, G. Melacini and P. Britz-McKibbin "Label-free Assay for Thermodynamic Analysis of Protein-ligand Interactions: A Multivariate Strategy for Allosteric Ligand Screening" Biochemistry 48, 223-225, 2009 (Rapid Reports).
K.R. Chalcraft and P. Britz-McKibbin"Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry: A Second-Tier Method with Improved Specificity and Sensitivity" Anal. Chem. 81, 307-314, 2009.
C. Kaiser, G. Segui-Lines, J.C. D’Amaral and P. Britz-McKibbin "Electrokinetic Probes for Single-step Screening of Polyol Stereoisomers: The Virtues of Ternary Boronate Ester Complexation” Chem. Commun. 338-340, 2008.
A.S. Ptolemy and P. Britz-McKibbin �gNew Advances in On-line Sample Preconcentration by Capillary Electrophoresis using Dynamic pH Junction�h Analyst 133, 1643-1648, 2008 (Highlight).
A.S. Ptolemy, R. Lee and P. Britz-McKibbin "Strategies for Comprehensive Analysis of Amino Acids as Biomarkers of Oxidative Stress” Amino Acids 33, 3-18, 2007(Invited Review).
G. Segui-Lines, J. M. A. Gavina, J. D’Amaral and P. Britz-McKibbin "High-throughput Screening of Holoprotein Conformational Stability by Dynamic Ligand Exchange-Affinity Capillary Electrophoresis” Analyst 132, 741-744, 2007(Communication).
E. Bernard, N. Gernigon and P. Britz-McKibbin "Resveratrol Photoisomerization: An Integrative Guided-Inquiry Experiment" J. Chem. Educ. 84, 1159-1161, 2007. (JCE Featured Molecule: Resveratrol)
P. Britz-McKibbin “Comprehensive Metabolomics by CE-MS: Strategies for Characterization of Unknown Low Abundance Metabolites” GIT Laboratory Journal Europe 5-6, 24-25, 2007(Invited Review).
R. Lee, A. S. Ptolemy, L. Niewzcas and P. Britz-McKibbin “Integrative Metabolomics for Characterizing Unknown Low Abundance Metabolites by Capillary Electrophoresis-Mass Spectrometry with Computer Simulations” Anal. Chem. 79, 403-415, 2007 (Accelerated Article). #9 Most Assessed Article in Analytical Chemistry: Jan-March 2007.
J. M. A. Gavina and P. Britz-McKibbin “Protein Unfolding and Conformational Studies by Capillary Electrophoresis” Current Analytical Chemistry 3, 17-31, 2007 (Invited Review) .
P. Britz-McKibbin �gComprehensive Metabolomics by CE-MS: Strategies for Characterization of Unknown Low Abundance Metabolites�h GIT Laboratory Journal, 5-6, 24-25, 2007.
P. Britz-McKibbin "High-throughput Screening by Capillary Electrophoresis" Laboratory Focus, 11, 4, 2007.
J. M. A. Gavina, R. Das and P. Britz-McKibbin “Dynamic Unfolding Studies of Regulatory Subunit of cAMP-Dependent Protein Kinase by Capillary Electrophoresis: Impact of cAMP Dissociation on Protein Stability” Electrophoresis 27, 4196-4124, 2006.
A. S. Ptolemy and P. Britz-McKibbin* "On-line Sample Preconcentration with Chemical Derivatization by Capillary Electrophoresis: Capillary as Preconcentrator, Microreactor and Chiral Selector for High-throughput Metabolite Screening" J. Chromatogr. A, 1106, 7-18, 2006 (Invited review).
P. Britz-McKibbin* “Capillary Electrophoresis: Steroids (Practical Applications)” Encyclopedia of Separation Science, Academic Press, Elsevier, 2006, (Invited Review - in press).
A. S. Ptolemy, L. Tran and P. Britz-McKibbin* "Single-step Enantioselective Amino Acid Flux Analyses in Bacteria by Capillary Electrophoresis with on-line Sample Preconcentration with Chemical Derivatization" Anal. Biochem. 354, 192-204, 2006.
S. Samson and P. Britz-McKibbin* "Enhanced Binding and Conformational Selectivity in Affinity Capillary Electrophoresis using a Water-soluble Recorcin[4]arene as an Intrinsic Buffer and Electrokinetic Host" Electrophoresis 27, 842-851, 2006.
A. S. Ptolemy, M. LeBihan and P. Britz-McKibbin* "On-line Sample Preconcentration with Chemical Derivtization of Bacterial Biomarkers by Capillary Electrophoresis: A Dual Strategy for Integrating Sample Pretreatment with Chemical Analysis" Electrophoresis, 26, 4206-4214, 2005.