当前位置: X-MOL首页全球导师 国内导师 › 陈伟

个人简介

入选国家、省等高级人才计划,先后负责国家蛋白质重大研究计划“青年 973 项目”、国家优秀青年基金项目,获得“树兰基金”医学青年人才奖、中美生物医学工程青年科学家奖(2019)(每 3 年 1 次, 每次中美各 1 人)等奖项;先后受邀在中国免疫学学会年会(2018)、全国生物力学大会(2018)和中美生物医学工程暨海内外生物力学研讨会(2019)上做大会主题报告。 教育经历 1997-2001 浙江大学电气工程学院 本科 2001-2003 浙江大学电气工程学院 硕士 2003-2009 美国 Georgia Insitute of Technology PhD (Bioengineering)

研究领域

膜蛋白动态识别及跨膜激活 单细胞及单分子生物医学工程 系统生物医学工程

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Lina Zhou*, Shuai Wang*, Wei Hu*, Xiaoqian Liu, Lingdong Xu, Bolu Tong, Tongtong Zhang, Zhonghui Xue, Yixin Guo, Jing Zhao, Linrong Lu, Hengyu Fan, Wenbin Qian, Jian Chen, Wei Chen#, Lie Wang#,T cell proliferation requires ribosomal maturation in nucleolar condensates dependent on DCAF13, Journal of Cell Biology, 2023; Rui Qin*, Chenyi An*, Wei Chen,Physical-chemical regulation of membrane receptors dynamics in viral invasion and immune defense,Journal of Molecular Biology, 2023; Hui Chen*, Xinyi Xu*, Wei Hu*, Songfang Wu, Jianhui Xiao, Peng Wu, Xiaowen Wang, Xuling Han, Yanruo Zhang, Yong Zhang, Ning Jiang, Wanli Liu, Changjie Lou, Wei Chen#, Chenqi Xu#, Jizhong Lou#, Self-programmed dynamics of T cell receptor condensation, PNAS, 2023; Lin Fan*, Junwei Liu*, Yang Zhang*, Chenyun Zhang, Beisheng Shi, Xinyang Hu, Wei Chen#, Weiwei Yin#, Jian’an Wang#,High-dimensional Single-cell Analysis Delineates Peripheral Immune Signature of Coronary Atherosclerosis in Human Blood, Theranostics, 2022; Xuyong Wei*, Wentao Xie*, Weiwei Yin*, Mengfan Yang * , Abdul Rehman Khan , Renyi Su, Wenzhi Shu , Binhua Pan , Guanghan Fan , Kun Wang , Fan Yang , Di Lu , Changbiao Li , Linhui Pan , Beini Cen, Haiyang Xie , Li Zhuang , Shusen Zheng , Xun Zeng# , Wei Chen#, Xiao Xu#, Prediction of tumor recurrence by distinct immunoprofiles in liver transplant patients based on mass cytometry, American journal of cancer research, 2022; Yinxuan Lei*, Panyu Fei*, Bin Song, Wenjia Shi, Cheng Luo, Dahai Luo, Dan Li#, Wei Chen#, Jie Zheng#, A loosened gating mechanism of RIG-I leads to autoimmune disorders, Nucleic Acids Research, 2022; Jiawei Shi, Junwei Liu, Xiaoxuan Tu, Bin Li, Zhou Tong, Tian Wang, Yi Zheng, Hongyu Shi, Xun Zeng#, Wei Chen#, Weiwei Yin# and Weijia Fang#, Single-Cell immune signature for detecting early-stage HCC and early assessing anti-PD-1 immunotherapy efficacy, Journal of Immunotherapy for Cancer, 2022; Juan Fan*, Jiawei Shi*, Yong Zhang*, Junwei Liu, Chenyi An, Huaying Zhu, Peng Wu, Wei Hu, Rui Qin, Danmei Yao, Xin Shou, Yibing Xu, Zhou Tong, Xue Wen, Jianpo Xu, Jin Zhang, Weijia Fang, Jizhong Lou#, Weiwei Yin#, Wei Chen#, NKG2D discriminates diverse ligands through selectively mechano‐regulated ligand conformational changes, EMBO J. , 2021; Panyu Fei, Haibo Ding, Yu Duan, Xinyi Wang, Wei Hu, Peng Wu, Mengxiao Wei, Zhengchun Peng#, Zhongze Gu#, Wei Chen#, Utility of TPP-manufactured biophysical restrictions to probe multiscale cellular dynamics, Bio-Design and Manufacturing, 2021; An Chenyi, Chen Wei, Multiplexed single-molecule force spectroscopy for dissecting biophysical regulation of membrane receptors functions on live cells, Biophysics Reports, 2021; Yan Shi#, Erdinc Sezgin#, Wei Chen#,The Role of Biomembranes and Biophysics in Immune Cell Signaling, Frontiers in Immunonlogy, 2021; Wei Hu*, Yong Zhang*, Panyu Fei*, Tongtong Zhang*, Danmei Yao*, Yufei Gao, Jia Liu, Hui Chen, Qiao Lu, Tenny Mudianto, Xinrui Zhang, Chuxuan Xiao, Yang Ye, Qiming Sun, Jing Zhang, Qi Xie, Pei-Hui Wang, Jun Wang#, Zhenhai Li#, Jizhong Lou#, Wei Chen#,Mechanical activation of spike fosters SARS-CoV-2 viral infection, Cell Research, 2021 Junwei Liu, Lulu Liu, Saisi Qu, Tongtong Zhang, Danyang Wang, Qinghua Ji, Tian Wang, Hongyu Shi, Kaichen Song, Weijia Fang, Wei Chen#, Weiwei Yin#, GdClean: removal of Gadolinium contamination in mass cytometry data, Bioinformatics, 2021; Tongtong Zhang*, Wei Hu*, Wei Chen, Plasma Membrane Integrates Biophysical and Biochemical Regulation to Trigger Immune Receptor Functions, Frontiers in Immunology 12, 53, 2021; J Liu, S Qu, T Zhang, Y Gao, H Shi, K Song, W Chen#, W Yin#, Applications of single-cell omics in tumor immunology, Frontiers in Immunology ,12, 2021; Hui Chen, Yang Cui, Xuling Han, Wei Hu, Min Sun, Yong Zhang, Pei-Hui Wang, Guangtao Song, Wei Chen#, Jizhong Lou#, "Liquid–liquid phase separation by SARS-CoV-2 nucleocapsid protein and RNA",Cell Research, 2020, Chenyi An*, Wei Hu*, Jie Gao, Bingfeng Ju, Peyman Obeidy, Yunduo Charles Zhao, Xiaoxuan Tu, Weijia Fang#, Lining Arnold Ju#, and Wei Chen#, "Ultra-stable biomembrane force probe for accurately determining slow dissociation kinetics of PD-1 blockade antibodies on single living cells", Nano Letter, 2020, Wei Hu*, Yong Zhang*, Xiaolin Sun*, Tongtong Zhang, Liling Xu, Hengyi Xie, Zhanguo Li, Wanli Liu#, Jizhong Lou#, Wei Chen#,"FcγRIIB-I232T polymorphic change allosterically suppresses ligand binding", eLife, 2019 Cheng Zhu#, Wei Chen, Jizhong Lou, William Rittase, Kaitao Li, Mechanosensing through immunoreceptors, Nat. Immun., 2019 20,1269-1278.; Peng Wu*, Tongtong Zhang*, Baoyu Liu*, Panyu Fei*, Lei Cui*, Rui Qin, Huaying Zhu, Danmei Yao, Ryan J Martinez, Wei Hu, Chenyi An, Yong Zhang, Junwei Liu, Jiawei Shi, Juan Fan, Weiwei Yin, Jie Sun, Chun Zhou, Xun Zeng, Chenqi Xu, Jianan Wang, Brian Evavold, Cheng Zhu, Wei Chen#$, Jizhong Lou#, "Mechano-regulation of Peptide-MHC Class I Conformations Determines TCR Antigen Recognition", Molecular Cell, 2019 Zhengpeng Wan, Chenguang Xu, Xiangjun Chen, Hengyi Xie, Zongyu Li, Jing Wang, Xingyu Ji, Haodong Chen, Qinghua Ji, Samina Shaheen, Yang Xu, Fei Wang, Zhuo Tang, Ji-Shen Zheng, Wei Chen, Jizhong Lou, Wanli Liu,"PI (4, 5) P2 determines the threshold of mechanical force–induced B cell activation",J Cell Biol,2018

推荐链接
down
wechat
bug