个人简介
2002年毕业于浙江大学医学院获预防医学专业学士学位;
2007年毕业于浙江大学医学院获博士学位,从事电磁场的生物学效应研究;
2007-2011年于加拿大UBC医学院从事临床肿瘤学方向的博士后研究;
2011年3月起,受聘浙江大学医学部,从事环境医学、肿瘤生物学和职业病学研究。
研究成果以第一作者和通讯作者身份发表于Oncogene、JID等SCI收录的Top期刊杂志论文20余篇;主持国家自然科学基金项目3项、省部级科研项目多项。
研究领域
1. 环境医学:环境污染(包括物理因素和化学因素)的生物学效应研究及健康风险评估。
2. 职业医学:职业性危害因素的控制评价,职业病和中毒的干预措施研究。
3. 肿瘤生物学:肿瘤标志物的筛选及其应用研究。
近期论文
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1. Jing Guo, Yue Fei, Junqin Li, Lisan Zhang, Qiong Luo, Guangdi Chen*. Duration and Prevalent Hypertension among Middle-aged and Elderly Chinese Adults, A Cross-sectional Study from CHARLS 2011-2012. BMJ Open 2016 In press.
2. Jing Guo, Liling Su, Xinyuan Zhao, Zhengping Xu, Guangdi Chen*. Relationships between urinary antimony levels and both mortalities and prevalence of cancers and heart diseases in general US population, NHANES 1999-2010. Sci Total Environ. 2016 Jul 8. [Epub ahead of print] (*Co-corresponding Authors) PMID: 27396316
3. Liling Su, Yue Fei, Xiaoxia Wei, Jing Guo, Xiangen Jiang*, Liqin Lu*, Guangdi Chen*. Associations of parental occupational exposure to extremely low-frequency magnetic fields with childhood leukemia risk. Leuk Lymphoma. 2016 Apr 7: 1-8. [Epub ahead of print] (*Co-corresponding Authors) PMID: 27054704
4. Dongyu Li, Xinyuan Zhao, Wei Qin, Hequn Zhang, Yue Fei, Liwei Liu, Ken-Tye Yong, Guangdi Chen*, Ben Zhong Tang*, Jun Qian*. Toxicity assessment and long-term three-photonfluorescence imaging of bright aggregation-inducedemission nanodots in zebrafish. Nano Research 2016, 9(7): 1921-1933. (*Co-corresponding Authors)
5. Li Jiang, Xinyuan Zhao, Yue Fei, Dongdong Yu, Jun Qian, Jinguang Tong, Guangdi Chen*, Sailing He*. The effects of magnetic fields exposure on relative permittivity of saline solutions measured by a high resolution SPR system.Sci Rep. 2016 Apr 28; 6: 25111. (*Co-corresponding Authors) PMID: 27121618
6. Zhaopin Wang, Lijuan Wang, Shuangshuang Zheng,Zheyuan Ding, Hui Liu, Wen Jin, Yifeng Pan, Zexin Chen, Ying Fei, Guangdi Chen, Zhengping Xu, Yunxian Yu*. Effects of electromagnetic fields on serum lipids in workers of a power plant. Environ Sci Pollut Res Int. 2016 Feb; 23(3): 2495-504. PMID: 26423285
7. Chen Lin, Xinyuan Zhao, Desen Sun, Lingda Zhang, Wenpan Fang, Tingjia Zhu, Qiang Wang, Botao Liu, Saisai Wei, Guangdi Chen, Zhengping Xu*, Xiangwei Gao*. Transcriptional activation of follistatin by Nrf2 protects pulmonary epithelial cells against silica nanoparticle-induced oxidative stress. Sci Rep. 2016 Feb 16; 6: 21133. (*Co-corresponding Authors) PMID: 26878911
8. Zhaopin Wang, Ying Fei, Hui Liu, Shuangshuang Zheng, Zheyuan Ding, Wen Jin, Yifeng Pan, Zexin Chen, Lijuan Wang, Guangdi Chen, Zhengping Xu, Yongjian Zhu, Yunxian Yu*. Effects of electromagnetic fields exposure on plasma hormonal and inflammatory pathway biomarkers in male workers of a power plant. Int Arch Occup Environ Health. 2016 Jan; 89(1):33-42. PMID: 25808749
9. Rongpan Bai, Chunhua Weng, Haojie Dong, Siqi Li, Guangdi Chen*, Zhengping Xu*. MicroRNA-409-3p suppresses colorectal cancer invasion and metastasis partly by targeting GAB1 expression. Int J Cancer. 2015 Nov 15; 137(10): 2310-22. (*Co-corresponding Authors) PMID: 25991585
10. Wen Sun, Liling Su, Yan Sheng, Ye Shen*, Guangdi Chen*. Is there association between Glutathione S Transferases polymorphisms and cataract risk: a meta-analysis? BMC Ophthalmology. 2015 Jul 26; 15: 84. (*Co-corresponding Authors) PMID: 26208492
11. Guohong Zhang, Yabin Cheng, Guangdi Chen, Yun Tang, Gholamreza Ardekani, Anand Rotte, Magdalena Martinka, Kevin McElwee, Xuezhu Xu, Qi Wang*, Youwen Zhou*. Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis. Oncotarget. 2015 Sep 8; 6(26): 23026-35. (*Co-corresponding Authors) PMID: 26246476
12. Jun Qian, Zhenfeng Zhu, Chris Wai Tung Leung, Wang Xi, Liling Su, Guangdi Chen, Anjun Qin, Ben Zhong Tang*, Sailing He*. Long-term two-photon neuroimaging with a photostable AIE luminogen. Biomed Opt Express. 2015 Mar 24; 6(4):1477-86. (*Co-corresponding Authors) PMID: 25909029
13. Yongdui Chen, Siqi Li, Liling Su, Jinghao Sheng, Wen Lv, Guangdi Chen*, Zhengping Xu*. Association of progranulin polymorphism rs5848 with neurodegenerative diseases: a meta-analysis. J Neurol. 2015 Apr;262(4):814-22. (*Co-corresponding Authors) PMID: 25578179
14. Yabin Cheng, Jing Lu, Guangdi Chen, Gholamreza Safaee Ardekani, Anand Rotte, Magdalena Martinka, Xuezhu Xu, Kevin J. McElwee, Guohong Zhang*, Youwen Zhou*. Stage-specific prognostic biomarkers in melanoma. Oncotarget. 2015 Feb 28;6(6):4180-9. (*Co-corresponding Authors) PMID: 25784655
15. Kanghui Li, Xinyuan Zhao, Yixing Zhai, Guangdi Chen, El-Hang Lee, Sailing He*. A Study on the Biocompatibility of Surface-Modified Au/Ag Alloyed Nanobox Particles in Zebrafish in Terms of Mortality Rate, Hatch Rate and Imaging of Particle Distribution Behavior. Progress In Electromagnetics Research. 2015, 150, 89-96.