曹戟 - 浙江大学

个人简介

1、学历背景 2008年9月至2013年12月，浙江大学药学院，药理学博士。 2004年9月至2008年6月，浙江大学，理学学士。 2、工作经历： 2014年1月-至今，浙江大学药学院，助理研究员

研究领域

主要围绕蛋白质的翻译后修饰开展抗肿瘤药物的新靶点发现及作用机制研究。

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1）Cao J #, Wang Y #, Dong R, Lin G, Zhang N, Wang J, Lin N, Gu Y, Ding L, Ying M, He Q, Yang B*. Hypoxia-Induced WSB1 Promotes the Metastatic Potential of Osteosarcoma Cells. 2015, Nov. Cancer research, 75(22): 4839-51. (TOP) 2）Cao J, Lou S, Ying M, Yang B*. DJ-1 as a human oncogene and potential therapeutic target. Biochemical Pharmacology. 2015 Feb 1;93(3):241-250. 3）Cao J #, Ying M #, Xie N, Lin G, Dong R, Zhang J, Yan H, Yang X, He Q, and Yang B *. The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-HPR: autophagy or apoptosis. Antioxidants & Redox Signaling. 2014 Jan 6. Epub ahead of print. (TOP) 4）Cao J, He L, Lin G, Hu C, Dong R, Zhang J, Zhu H, Hu Y, Wagner CR, He Q, Yang B*. Cap-dependent Translation Initiation Factor, eIF4E, is the Target for Ouabain-Mediated Inhibition of HIF-1α. Biochem Pharmacol. 2014 May 1;89(1):20-30. 5）Zhang J#, Cao J #, Ma S, Dong R, Meng W, Ying M, Weng Q, Chen Z, Ma J, Fang Q, He Q, and Yang B*. Tumor hypoxia enhances Non-Small Cell Lung Cancer metastasis by selectively promoting macrophage M2 polarization through the activation of ERK signaling. Oncotarget. 2014 Oct 30;5(20):9664-77. (Co-First) 6）Cao J, Xu D, Wang D, Wu R, Zhang L, Zhu H, He Q, Yang B.ROS-driven Akt dephosphorylation at Ser-473 is involved in 4-HPR-mediated apoptosis in NB4 cells. Free Radic Biol Med. 2009 Sep 1;47(5):536-47. 7）Zhang J#, Cao J#, Weng Q, Wu R, Yan Y, Jing H, Zhu H, He Q, Yang B. Suppression of hypoxia-inducible factor 1α (HIF-1α) by tirapazamine is dependent on eIF2α phosphorylation rather than the mTORC1/4E-BP1 pathway. PLoS One. 2010 Nov 9;5(11):e13910.(Co-First) 8）Cao J, Zhang L, Ye Q, Zhou X, Lou J, Zhu D, Hu Y, He Q, Yang B. YQ36: a novel bisindolylmaleimide analogue induces KB/VCR cell death. J Biomed Biotechnol. 2009;2009:535072.