个人简介
1、学历背景: 2000-2005:浙江大学药学院药理学专业,获医学博士学位 1996-2000:浙江大学药学院药学专业,获理学学士学位
2、国外学习研究经历: 2009.10-2010.2 美国洛克菲勒大学人口与健康研究中心 访问学者
3、工作经历: 2005-2007:浙江大学药学院,师资博士后,讲师。评为浙江大学2007年优秀博士后 2007-至今:浙江大学药学院,副研究员
研究领域
1. 干细胞生物学及在组织工程和药物调控中的应用。研究干细胞定向分化过程中,功能基因组和蛋白组表达及相关信号通路调控,并探索药物诱导分化作用。
2. 防治重大疾病的中药主治功效分子基础研究和新药研发。
近期论文
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1)Dan-yan Zhu,* Jia-ying Wu, Huan Li, Jie-ping Yan, Mei-yuan Guo, Yan-bo Wo, and Yi-jia Lou. PPAR- Facilitating Maturation of Hepatic-Like Tissue Derived From Mouse Embryonic Stem Cells Accompanied by Mitochondriogenesis and Membrane Potential Retention. Journal of Cellular Biochemistry 2009, 9999:1-11.
2)DAN-YAN ZHU, YUE DU, XIN HUANG, MEI-YUAN GUO, KUI-FEN MA, YONG-PING YU, YI-JIA LOU. MAPEG Expression in Mouse Embryonic Stem Cell-Derived Hepatic Tissue System. Stem Cells and Development, 2008, 2008; 17: 775-784.
3)Yan-bo Wo, Dan-yan Zhu(并列第一作者), Ying Hu , Zhi-Qiang Wang, Jian Liu ,and Yi-Jia Lou (Yan-bo Wo, Dan-yan Zhu contributed equally to this work).Reactive oxygen species involved in prenylflavonoids, icariin and icaritin, initiated cardiac differentiation of mouse embryonic stem cells. Journal of Cellular Biochemistry,2008,103:1536-1550.
4)Danyan Zhu, Yijia Lou. Icariin-mediated expression of cardiac genes and modulation of nitric oxide signaling pathway during differentiation of mouse embryonic stem cells into cardiomyocytes in vitro. Acta Pharmacologica Sinica 2006, 27: 311-320.
5)Danyan Zhu, Linhai Qu, Xiangnan Zhang, Yijia Lou. Icariin-madiated modulation of cell cycle and p53 during cardiomyocyte differentiation in embryonic stem cells. European J Pharmacology 2005, 514: 99-110.