孙莲莉 - 浙江大学

个人简介

一、工作经历： 2014.06-至今浙江大学药学院副教授 2012.06-2014.5 浙江大学生仪学院讲师 2009.05-2012.05 浙江大学药学院博士后 2008.07-2009.04 德国美因茨大学药学院博士后二、教育经历： 2005.09-2008.06 德国美因茨大学药学院生物制药专业（联合培养） 2003.09-2008.06 浙江大学药学院药物分析专业理学博士 1999.09-2003.06 浙江大学药学院药学专业理学学士

研究领域

运用结构生物学和分子生物学的方法对天然活性代谢酶进行系统研究，包括酶克隆、表达、纯化、结晶及三维结构解析。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. L Sun, M Luan, W Zhu, S Gao, Q Zhang, C Xu, X Lu, X Xu, J Tian, L Zhang. Study on antitubercular constituents from the seeds of Nigella glandulifera, Chem. Pharm. Bull., 2013, 61, 873-876. 2. L Sun, Y Chen, C Rajendran, U Mueller, S Panjikar, M Wang, R Mindnich, C Rosenthal, TM Penning, J Stöckigt. Crystal structure of perakine reductase, a founding member of a novel aldo-keto reductase (AKR) subfamily which undergoes unique conformational changes during NADPH binding,J. Biol. Chem. 2012, 287, 11213-11221. 3. F Wu‡, H Zhu‡, L Sun‡, C Rajendran, M Wang, X Ren, S Panjikar, A Cherkasov, H Zou, J Stöckigt. Scaffold tailoring by a newly detected Pictet−Spenglerase activity of strictosidine synthase: from the common tryptoline skeleton to the rare piperazino-indole framework. J. Am. Chem. Soc. 2012, 134, 1498-1500.(‡ Co-first) 4. L Zhang, X Li, W Zheng, Z Fu, W Li, L Ma, K Li, L Sun, J Tian. Proteomics analysis of UV-irradiated Lonicera japonica Thunb. with bioactive metabolites enhancement. Proteomics, 2013, 13, 3508-3522. 5. Z Fu, L Zhang, X Liu, Y Zhang, Q Zhang, X Li, W Zheng,L Sun, J Tian. Comparative proteomic analysis of the sun- and freeze-dried earthworm Eisenia fetida with differentially thrombolytic activities.J. Proteomics, 2013, 83, 1-14. 6. X Wang, L Sun, K Huang, S Shi, L Zhang, J Xu, H Peng, X Sun, L Wang, X Wu, Y Zhao, X Li, J Stöckigt, J Qu. Phytochemical investigation and cytotoxic evaluation of the components of the medicinal plant Ligularia atroviolace. Chemistry & Biodiversity, 2009, 6, 1053-1065. 7. L Sun, M Ruppert, Y Sheludko, H Warzecha, Y Zhao, J Stöckigt. Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia,Plant Mol. Biol. 2008, 67, 455-467