陈文腾 - 浙江大学

个人简介

1. 学历背景 2004/09-2008/06，厦门大学，医学院，药学专业，本科/理学学士 2008/09-2013/06，浙江大学，药学院，药物化学，研究生/医学博士 2. 国外学习研究经历 2010/08-2011/09，美国Torrey Pines Institute for Molecular Studies，访问学者 3.工作经历 2013/07-2015/06，浙江大学，药学院，药理毒理与生化研究所，博士后 2015/07-至今，浙江大学，药学院，药物发现与设计研究所，助理研究员

研究领域

1. 靶向抗肿瘤新策略研究 2. 多肽及蛋白质合成新方法 3. 类药性杂环化合物库的构建

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Jiaan Shao, Xingyu Liu, Ke Shu, Pai Tang, Jing Luo, Wenteng Chen,* and Yongping Yu*, Tuning the annulation reactivity of vinyl azides and carbazates: A divergent synthesis of aza-pyrimidinones and imidazoles. Org. Lett. 2015, 17，4502-4505. 2. Guangxin Xia, Wenteng Chen, Jing Zhang, Jiaan Shao, Yong Zhang, Wei Huang, Leduo Zhang, Weixing Qi, Xing Sun, Bojun Li, Zhixiong Xiang, Chen Ma, Jia Xu, Hailin Deng, Yufeng Li, Ping Li, Hong Miao, Jiansheng Han, Yanjun Liu, Jingkang Shen,* and Yongping Yu*, A chemical tuned strategy to develop novel irreversible EGFR-TK inhibitors with improved safety and pharmacokinetic profiles. J. Med. Chem. 2014, 57, 9889-9900. (coauthor） 3. Shen Liu, Wenteng Chen, Jing Luo, Yongping Yu * [3+3] annulation of allylic phosphoryl-stabilized carbanions/phosphorus ylides and vinyl azides: a practice strategy for synthesis of polyfunctionalized anilines. Chem. Commun. 2014，50, 8539-8542. (coauthor) 4. Wenteng Chen, Jiaan Shao, Miao Hu, Wanwan Yu, Marc A. Giulianotti, Richard A. Houghten *, Yongping Yu* A traceless approach to amide and peptide construction from thioacids and dithiocarbamate-terminal amines. Chem. Sci.2013, 4, 970-976. 5. Jianwei Wu, Wenteng Chen, Guangxin Xia, Jing Zhang, Jiaan Shao, Biqin Tan, Chunchun Zhang, Wanwan Yu, Qinjie Weng, Haiyan Liu, Miao Hu, Hailin Deng, Yu Hao, Jingkang Shen*, Yongping Yu * Design, synthesis, and biological evaluation of novel conformationally constrained inhibitors targeting EGFR. ACS Med. Chem. Lett. 2013, 4, 974-978. (coauthor) 6. Wenteng Chen, Miao Hu, Jianwei Wu, Hongbin Zou*, Yongping Yu* Domino approach for the synthesis of pyrrolo[1,2-α] pyrazine from vinyl azides. Org. Lett., 2010, 12, 3863–3865.（被Synfacts作为亮点报道）