研究领域

Interdisciplinary frontiers of microfluidics, bioanalytical science and materials chemistry. MEMS, microfluidics, soft lithography, and surface chemistry to design and provide new tools for the applications and understanding of fundamentals in materials and biological sciences, including microfluidic chemical reactors, high throughput single-cell analysis and chemical separations.

Dr Wu’s research focuses on the interdisciplinary frontiers of microfluidics, bioanalytical science and materials chemistry. We use the technologies in MEMS, microfluidics, soft lithography, and surface chemistry to design and provide new tools for the applications and understanding of fundamentals in materials and biological sciences, including microfluidic chemical reactors, high throughput single-cell analysis and chemical separations.

近期论文

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Li, H.; Cheng, J.; Deng, H.; Zhao, E.; Shen, B.; Lam, J. W. Y.; Wong, K. S.; Wu, H.; Li, B. S.*; Tang, B. Z.*, Aggregation-Induced Chirality, Circularly Polarized Luminescence, and Helical Self-Assembly of a Leucine-Containing AIE Luminogen. Journal of Materials Chemistry C, 2015, in press. Chen, Y.; Wang, J.; Shen, B.; Chan, C. W. Y.; Wang, C.; Zhao, Y.; Chan, H. N.; Tian, Q.; Chen, Y.; Yao, C.; Hsing, I. M.; Li, R. A.*; Wu, H.*, Engineering a freestanding biomimetic cardiac patch using biodegradable poly(lactic-co-glycolic acid) (PLGA) and human embryonic stem cell-derived ventricular cardiomyocytes (hESC-VCMs). Macromolecular Bioscience 2015, in press. Ketov, S. V.*; Shi, X.; Xie, G.; Kumashiro, R.; Churyumov, A. Y.; Bazlov, A. I.; Chen, N.; Ishikawa, Y.; Asao, N.; Wu, H.*, Louzguine-Luzgin, D. V., Nanostructured Zr-Pd Metallic Glass Thin Film for Biochemical Applications. Scientific Reports 2015, 5, in press. Chen, Y.; Cao, W.; Zhou, J.; Pidhatika, B.; Xiong, B.; Huang, L.; Tian, Q.; Shu, Y.; Wen, W.; Hsing, I.-M.; Wu, H.*, Poly (L-lysine)-graft-folic acid-coupled poly (2-methyl-2-oxazoline)(PLL-g-PMOXA-c-FA): a novel bioactive copolymer for specific targeting to folate receptor-positive cancer cells. ACS applied Materials & Interfaces 2015, in press. Chan, H. N.; Chen, Y.; Shu, Y.; Chen, Y.; Tian, Q.; Wu, H.*, Direct, one-step molding of 3D-printed structures for convenient fabrication of truly 3D PDMS microfluidic chips. Microfluidics and Nanofluidics 2015, 1-10. Xiong, B.; Chen, Y.; Shu, Y.; Shen, B.; Chan, H. N.; Chen, Y.; Zhou, J.; Wu, H.*, Highly emissive and biocompatible dopamine-derived oligomers as fluorescent probes for chemical detection and targeted bioimaging. Chemical Communications 2014, 50, 13578-13580. Li, H.; Cheng, J.; Zhao, Y.; Lam, J. W. Y.; Wong, K. S.; Wu, H.; Li, B. S.*; Tang, B. Z.*, L-Valine methyl ester-containing tetraphenylethene: aggregation-induced emission, aggregation-induced circular dichroism, circularly polarized luminescence, and helical self-assembly. Materials Horizons 2014, 1, 518-521. Ahadian, S.; Ramón-Azcón, J.; Chang, H.; Liang, X.; Kaji, H.; Shiku, H.; Nakajima, K.; Ramalingam, M.; Wu, H.; Matsue, T.; Khademhosseini, A.*, Electrically regulated differentiation of skeletal muscle cells on ultrathin graphene-based films. RSC Advances 2014, 4, 9534-9541. Chen, S.*; Zhang, H.; Shi, X.; Wu, H.*; Hanagata, N.*, Microfluidic generation of chitosan/CpG oligodeoxynucleotide nanoparticles with enhanced cellular uptake and immunostimulatory properties. Lab on a Chip 2014, 14, 1842-1849. Chang, H.*; Kang, J.*; Chen, L.; Wang, J.; Ohmura, K.; Chen, N.; Fujita, T.; Wu, H.*; Chen, M., Low-temperature solution-processable Ni(OH)2 ultrathin nanosheet/N-graphene nanohybrids for high-performance supercapacitor electrodes. Nanoscale 2014, 6, 5960-5966. Qiu, Y.; Zhao, Y.; Yang, X.; Li, W.; Wei, Z.; Xiao, J.; Leung, S.-F.; Lin, Q.; Wu, H.; Zhang, Y.*; Fan, Z.*; Yang, S.*, Three-dimensional metal/oxide nanocone arrays for high-performance electrochemical pseudocapacitors. Nanoscale 2014, 6, 3626-3631. Ren, K.; Chen, Y.; Wu, H.*, New materials for microfluidics in biology. Current Opinion in Biotechnology 2014, 25, 78-85. Ruan, Q.; Shao, L.; Shu, Y.; Wang, J.*; Wu, H.*, Growth of Monodisperse Gold Nanospheres with Diameters from 20 nm to 220 nm and Their Core/Satellite Nanostructures. Advanced Optical Materials 2014, 2, 65-73. Shi, X.; Fujie, T.; Saito, A.; Takeoka, S.; Hou, Y.; Shu, Y.; Chen, M.; Wu, H.*; Khademhosseini, A.*, Periosteum-Mimetic Structures Made from Freestanding Microgrooved Nanosheets. Advanced Materials 2014, 26, 3290-3296. Shi, X.; Ostrovidov, S.; Shu, Y.; Liang, X.; Nakajima, K.; Wu, H.*; Khademhosseini, A.*, Microfluidic generation of polydopamine gradients on hydrophobic surfaces. Langmuir 2014, 30, 832-838. Xiong, B.; Ren, K.; Shu, Y.; Chen, Y.; Shen, B.; Wu, H.*, Recent Developments in Microfluidics for Cell Studies. Advanced Materials 2014, 26, 525-5532. Zhou, J.; Hyun, D. C.; Liu, H.; Wu, H.*; Xia, Y.*, Protein Capsules with Cross-Linked, Semipermeable, and Enzyme-Degradable Surface Barriers for Controlled Release. Macromolecular Rapid Communications 2014, 35, 1436-1442. Shi, X.*; Li, L.; Ostrovidov, S.; Shu, Y.; Khademhosseini, A.; Wu, H.*, Stretchable and micropatterned membrane for osteogenic differentiation of stem cells. ACS Applied Materials & Interfaces 2014, 6, 11915-11923. Chang, H.*; Wu, H.*, Graphene-based nanomaterials: synthesis, properties, and optical and optoelectronic applications. Advanced Functional Materials 2013, 23, 1984-1997. Chen, Y.; Cao, W.; Wen, W.; Hsing, I. M.; Wu, H.*, Folic acid coupled poly(L-lysine)-graft-(poly(2-methyl-2-oxazoline)(FA-C-PLL-G-PMOXA): a novel copolymer for specific targeting to folate receptor-positive tumor cells. 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, 27-31 Oct. 2013, Freiburg, Germany, 1015-1017."