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Bioorganic chemistry Biophysical chemistry Biosynthesis of menaquinone Chemical biology Structural biology

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Thiamine carbene liganded gold(i) chloride catalyzes an efficient aldehyde–alkyne–amine coupling reaction in water. Author(s): Narra, Rajashekar ; Unnithan, Vignesh Gopalakrishnan ; Wong, Ting Hei ; Guo, Zhihong View this author's profile. Source: Green Chemistry, v. 25, (5), February 2023, p. 1920-1924 Fast Delivery of Multifunctional NIR-II Theranostic Nanoaggregates Enabled by the Photoinduced Thermoacoustic Process. Author(s): Xie, Huilin ; Zhang, Chen ; Li, Tingting ; Hu, Lianrui ; Zhang, Jianquan ; Guo, Heng ; Liu, Zhao ; Peng, Dinglu ; Li, Zeshun ; Wu, Weijun ; Gao, Ji ; Bi, Zhenyu ; Wang, Jinghan ; Zhang, Pengfei ; Kwok, Tsz Kin View this author's profile ; Lam, Wing Yip View this author's profile ; Guo, Zhihong View this author's profile ; Xi, Lei ; Li, Kai ; Tang, Benzhong View this author's profile. Source: Advanced Science, April 2023, article number 2301104 Water-Soluble Aggregation-Induced Emission Luminogens with Near-Infrared Emission for Advanced Phototheranostics. Author(s): Shen, Hanchen ; Xu, Changhuo ; Ye, Ruquan ; Liu, Tzu-Ming ; Zhang, Jianyu ; Kwok, Ryan T. K. View this author's profile ; Lam, Jacky W. Y. View this author's profile ; Guo, Zhihong View this author's profile ; Sun, Jianwei View this author's profile ; Tang, Benzhong View this author's profile. Source: Small Science, v. 3, (9), September 2023, article number 2300052 Phenylacetyl pepstatin inhibitors of aspartyl proteases from Streptomyces varsoviensis. Author(s): Ye, Weijian ; Guo, Zhihong View this author's profile. Source: Journal of Antibiotics, v. 75, (9), September 2022, p. 519-522 Cry3Aa*SpyCatcher Fusion Crystals Produced in Bacteria as Scaffolds for Multienzyme Coimmobilization. Author(s): Sun, Qian ; Heater, Bradley S. ; Li, Tin Lok View this author's profile ; Ye, Weijian ; Guo, Zhihong View this author's profile ; Chan, Michael K.. Source: Bioconjugate Chemistry, v. 33, (2), February 2022, p. 386-396 Listeria monocytogenes MenI Encodes a DHNA-CoA thioesterase necessary for menaquinone biosynthesis, cytosolic survival, and virulence. Author(s): Smith, Hans B. ; Li, Tin Lok View this author's profile ; Liao, Man Kit ; Chen, Grischa Y. ; Guo, Zhihong View this author's profile ; Sauer, John-Demian. Source: Infection and Immunity, v. 89, (5), April 2021, article number e00792-20 A tough nitric oxide-eluting hydrogel coating suppresses neointimal hyperplasia on vascular stent. Author(s): Chen, Yin ; Gao, Peng ; Huang, Lu ; Tan, Xing ; Zhou, Ningling ; Yang, Tong ; Qiu, Hua ; Dai, Xin ; Michael, Sean ; Tu, Qiufen ; Huang, Nan ; Guo, Zhihong View this author's profile ; Zhou, Jianhua ; Yang, Zhilu ; Wu, Hongkai View this author's profile. Source: Nature Communications, v. 12, (1), December 2021, article number 7079 Substrate recognition and catalytic mechanism of the phosphate acyltransferase PlsX from Bacillus subtilis. Author(s): Jiang, Yiping ; Qin, Mingming ; Guo, Zhihong View this author's profile. Source: ChemBioChem, v. 21, 2020 Identification of an amphipathic peptide sensor of the Bacillus subtilis fluid membrane microdomains. Author(s): Jiang, Yiping ; Dai, Xin ; Qin, Mingming ; Guo, Zhihong View this author's profile. Source: Communications Biology, v. 2, (1), August 2019, article number 316 Single-Turnover Kinetics Reveal a Distinct Mode of Thiamine Diphosphate-Dependent Catalysis in Vitamin K Biosynthesis. Author(s): Qin, Mingming ; Song, Haigang ; Dai, Xin ; Chan, Chi Kong ; Chan, Wan View this author's profile ; Guo, Zhihong View this author's profile. Source: ChemBioChem, v. 19, (14), July 2018, p. 1514-1522 Two Active Site Arginines Are Critical Determinants of Substrate Binding and Catalysis in MenD: A Thiamine-dependent Enzyme in Menaquinone Biosynthesis. Author(s): Qin, Mingming ; Song, Haigang ; Dai, Xin ; Chen, Yaozong ; Guo, Zhihong View this author's profile. Source: Biochemical Journal, v. 475, (22), November 2018, p. 3651-3667 Crystal Structure of the Thioesterification Conformation of Bacillus Subtilis O-succinylbenzoyl-CoA Synthetase Reveals a Distinct Substrate-binding Mode. Author(s): Chen, Yaozong ; Li, Tin Lok View this author's profile ; Lin, Xingbang ; Li, Xin ; Li, Xiang David ; Guo, Zhihong View this author's profile. Source: Journal of Biological Chemistry, v. 292, (29), July 2017, p. 12296-12310 Facile Formation of a Microporous Chitosan Hydrogel Based on Self-crosslinking. Author(s): Chen, Yin ; Huang, Lu ; Dai, Xin ; Tian, Qian ; Yu, Miao ; Agheb, Maria ; Chan, Ho Nam ; Poon, ellen ; Guo, Zhihong View this author's profile ; Boheler,kenneth richard ; Wu, Hongkai View this author's profile. Source: Journal of Materials Chemistry B, v. 5, (47), December 2017, p. 9291-9299 Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate. Author(s): Chen, Yaozong ; Jiang, Yiping ; Guo, Zhihong View this author's profile. Source: Biochemistry, v. 55, (48), December 2016, p. 6685-6695 A Thiamine-Dependent Enzyme Utilizes an Active Tetrahedral Intermediate in Vitamin K Biosynthesis. Author(s): Song, Haigang ; Dong, Chen ; Qin, Mingming ; Chen, Yaozong ; Sun, Yueru ; Liu, Jingjing ; Chan, Wan View this author's profile ; Guo, Zhihong View this author's profile. Source: Journal of the American Chemical Society, v. 138, (23), June 2016, p. 7244-7247 A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Author(s): Song, Juxian ; Sun, Yueru ; Peluso, Ivana ; Zeng, Yu ; Yu, Xing ; Lu, Jiahong ; Xu, Zheng ; Wang, Mingzhong ; Liu, Liangfeng ; Huang, Yingyu ; Chen, Leilei ; Durairajan, Siva Sundara Kumar ; Zhang, Hongjie ; Zhou, Bo ; Zhang, Hongqi ; Lu, Aiping ; Ballabio, Andrea ; Medina, Diego Luis ; Guo, Zhihong View this author's profile ; Li, Min. Source: Autophagy, v. 12, (8), August 2016, p. 1372-1389 An Atypical α/β-Hydrolase Fold Revealed in the Crystal Structure of Pimeloyl-Acyl Carrier Protein Methyl Esterase BioG from Haemophilus Influenzae. Author(s): Shi, Jie ; Cao, Xinyun ; Chen, Yaozong ; Cronan, John E. ; Guo, Zhihong View this author's profile. Source: Biochemistry, v. 55, (48), December 2016, p. 6705-6717 Identification and Characterization of a Methionine gamma-Lyase in the Calicheamicin Biosynthetic Cluster of Micromonospora echinospora. Author(s): Song, Haigang ; Xu, Ri ; Guo, Zhihong View this author's profile. Source: ChemBioChem, v. 16, (1), 2015, p. 100-109 Microsecond Protein Folding Events Revealed by Time-Resolved Fluorescence Resonance Energy Transfer in a Microfluidic Mixer. Author(s): Jiang, Liguo ; Zeng, Yan ; Sun, Qiqi ; Sun, Yueru ; Guo, Zhihong View this author's profile ; Qu, Jianan View this author's profile ; Yao, Shuhuai View this author's profile. Source: Analytical Chemistry, v. 87, (11), June 2015, p. 5589-5595 Structural basis for the ATP-dependent configuration of adenylation active site in Bacillus subtilis o-Succinylbenzoyl-CoA synthetase. Author(s): Chen, Yaozong ; Sun, Yueru ; Song, Haigang ; Guo, Zhihong View this author's profile. Source: Journal of Biological Chemistry, v. 290, (39), September 2015, p. 23971-23983

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