个人简介

10/1978-7/1982 Department of Chemistry, Hangzhou University (currently Zhejiang University), Hangzhou, China BSc, July, 1982 8/1982-9/1985 Shanghai Institute of Organic Chemistry, The Chinese Academy of Sciences, Shanghai, China MSc, December 1984; Supervisor: Prof. Wei-Shan Zhou [Memorial Page] [Special Issue in Chin. J. Chem.] [photo#1; #2; #3] 10/1985-4/1990 Institute for Chemical Research, Kyoto University, Japan PhD, 23 March 1990; Supervisor: Prof. Yoshimitsu Nagao Appointments: 5/1990-8/1992 Research Associate, Department of Chemistry, The Scripps Research Institute, La Jolla, USA Prof. K. C. Nicolaou's group, involved in studies on enediynes and taxol. [photos#1; #2; #3] 9/1992-12/1997 Assistant Professor, Department of Chemistry, The Hong Kong University of Science and Technology 1/1998-6/2007 Associate Professor, Department of Chemistry, The Hong Kong University of Science and Technology 7/2007-present Professor, Department of Chemistry & Center for Cancer Research, The Hong Kong University of Science and Technology

研究领域

Synthetic organic and bioorganic chemistry. Chirality & catalysis, and synthesis of bioactive molecules including diverted total synthesis of natural products.

Asymmetric catalysis and enantioselective reactions; diverted total synthesis of natural products and biomedically interesting molecules; studies on diversity-oriented synthesis of privileged heterocyclic scaffolds, microwave-assisted solid phase organic synthesis (MASPOS), combinatorial synthesis, and applications in chemical biology and chemical genetics.

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Synthesis of 5-Alkyl-5-aryl-1-pyrroline N-Oxides from 1-Aryl-Substituted Nitroalkanes and Acrolein via Michael Addition and Nitro Reductive Cyclization: Jingjing Xu, Xingyao Li, Jinlong Wu,* and Wei-Min Dai,* Tetrahedron 2014, 70, 6384–6391. [DOI: 10.1016/j.tet.2014.07.046] One-Pot Synthesis of Dibenz[b,f][1,4]oxazepines via Mg(ClO4)2-Catalyzed Ugi Four-Component Reaction and Microwave-Assisted Intramolecular SNAr: Jialu Luo, Jinlong Wu, and Wei-Min Dai,* Diversity Oriented Synthesis 2014, 1, 29–34. [DOI: 10.2478/dos-2014-0001] Synthesis of Highly Functionalized Benzofuran-2-carboxamides by Ugi Four-Components Reaction and Microwave-Assisted Rap–Stoermer Reaction: Weiwei Han, Jinlong Wu, and Wei-Min Dai,* Synlett 2014, 25, 2019–2024. [DOI: 10.1055/s-0034-1378351] Synthesis of 5-Alkyl-5-aryl-g-lactams from 1-Aryl-Substituted Nitroalkanes and Methyl Acrylate via Michael Addition and Reductive Lactamization: Jingjing Xu, Xingyao Li, Jinlong Wu,* and Wei-Min Dai,* Tetrahedron 2014, 70, 3839–3846. [DOI: 10.1016/j.tet.2014.04.074] Highlighted in Synfacts 2014, 10, 803. [DOI: 10.1055/s-0034-1378443] Synthesis of the Conjugated Tetraene Acid Side Chain of Mycolactone E by Suzuki–Miyaura Cross-Coupling Reaction of Alkenyl Boronates: Yuan Wang and Wei-Min Dai,* Eur. J. Org. Chem. 2014, 323–330. [Cover Picture] [DOI: 10.1002/ejoc.201301484] Increasing Appendage Diversity on 3,4-Dihydro-3-oxo-2H-1,4-benzoxazines via Aphos–Pd(OAc)2-Catalyzed Suzuki–Miyaura Cross-Coupling of Aryl Chlorides: Gongli Yu, Yu Zheng, Jinlong Wu, and Wei-Min Dai,* Tetrahedron 2013, 69, 10488–10496. [DOI: 10.1016/j.tet.2013.09.057] An Efficient and Reliable Catalyst System Using Hemilabile Aphos for B-Alkyl Suzuki–Miyaura Cross-Coupling Reaction with Alkenyl Halides: Ning Ye and Wei-Min Dai,* Eur. J. Org. Chem. 2013, 831–835. [Cover Picture] [DOI: 10.1002/ejoc.201201602] A Concise Total Synthesis of Amphidinin B: Dongdong Wu, Jinlong Wu, and Wei-Min Dai,* Chin. J. Chem. 2013, 31, 105–110. [Cover Picture] [DOI: 10.1002/cjoc.201201069] Review: Generation of Molecular Shape Diversity. From Privileged Scaffolds to Diverted Total Synthesis: Wei-Min Dai,* Diversity Oriented Synthesis 2012, 1, 11–20. [DOI: 10.2478/dos-2012-0003] Toward a Total Synthesis of Divergolide A; Synthesis of the Amido Hydroqunione Core and the C10–C15 Fragment: Guanglian Zhao, Jinlong Wu, and Wei-Min Dai,* Synlett 2012, 2845–2849. [DOI: 10.1055/s-0032-1317491] Concise Diverted Total Synthesis of Amphidinolide T1 and T4 from a (12E)-Cycloalkene by Selective Functionalized of the C12–C13 Double Bond: Lijie Sun, Dongdong Wu, Jinlong Wu, and Wei-Min Dai,* Synlett 2011, 3036–3040. [DOI: 10.1055/s-0031-1289903] Determination of Absolute Configuration of 2-Methyl-1-(o-tolyl)naphthalene and the Related Axially Chiral Biaryls: Lijie Sun and Wei-Min Dai,* Tetrahedron 2011, 67, 9072–9079. [DOI: 10.1016/j.tet.2011.09.107] In(OTf)3-Catalyzed Highly Chemo- and Regioselective Head-to-Tail Heterodimerization of Vinylarenes with 1,1-Diarylethenes: Jing Dai, Jinlong Wu, Guanglian Zhao, and Wei-Min Dai,* Chem. Eur. J. 2011, 17, 8290–8293. [DOI: 10.1002/chem.201101190] Synthesis of Two Diastereoisomers of Iriomoteolide-1a via a Tunable Four-Module Coupling Approach Using Ring-Closing Metathesis as the Key Step: Yuanxin Liu, Gaofeng Feng, Jian Wang, Jinlong Wu, and Wei-Min Dai,* Synlett 2011, 1774–1778. [DOI: 10.1055/s-0030-1260822] Total Synthesis of Amphidinolide T3 Using Ring-Closing Metathesis and Asymmetric Dihydroxylation Strategy: Dongdong Wu, Huoiming Li, Jian Jin, Jinlong Wu, and Wei-Min Dai,* Synlett 2011, 895–898 [DOI: 10.1055/s-0030-1259706] [special issue dedicated to Professors Xiyan Lu and Li-Xin Dai] Tandem Wittig–Intramolecular Diels–Alder Cycloaddition of Ester-Tethered 1,3,9-Decatrienes under Microwave Heating: Jinlong Wu, Xiuqing Jiang, Jingjing Xu, and Wei-Min Dai,* Tetrahedron 2011, 67, 179–192. [DOI: 10.1016/j.tet.2010.10.088] A Concise Total Synthesis of Amphidinolide T2: Huoming Li, Jinlong Wu, Jialu Luo, and Wei-Min Dai,* Chem. Eur. J. 2010, 16, 11530–11534. [DOI: 10.1002/chem.201001794] Synthesis of Anti-Microtubule N-(2-Arylindol-7-yl)benzenesulfonamide Derivatives and Their Antitumor Mechanisms: Chun-Tang Chiou, Grace Shiahuy Chen, Meng-Ling Chen, Huoming Li, Lei Shi, Xiang-Hong Huang, Wei-Min Dai, and Ji-Wang Chern,* ChemMedChem, 2010, 5, 1489–1497. [DOI: 10.1002/cmdc.201000228] Synthesis of the C7–C23 Fragment Related to Iriomoteolide-1a via B-Alkyl Suzuki–Miyaura Cross-Coupling and Indium-Mediated Aldehyde Allylation: Yuanxin Liu, Jian Wang, Huoming Li, Jinlong Wu, Gaofeng Feng, and Wei-Min Dai,* Synlett 2010, 2184–2188. [DOI: 10.1055/s-0030-1258507] Synthesis of N-Arylisoindolin-1-ones via Pd-Catalyzed Intramolecular Decarbonylative Coupling of N-(2-Bromobenzyl)oxanilic Acid Phenyl Esters: Yu Zheng, Gongli Yu, Jinlong Wu, and Wei-Min Dai,* Synlett 2010, 1075–1080. [DOI: 10.1055/s-0029-1219580]"