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Chemoselective and Diastereoselective Intramolecular (3+2) Cycloadditions of Epoxy and Aziridinyl Enolsilanes. Chen, Y.; Ling, J.; Keto, A. B.; He, Y.; Low, K. H.; Krenske, E. H.;* Chiu, P.* Angew. Chem. Int. Ed. 2022, e202116099. Direct Asymmetric Reductive Amination of α-Keto Acetals: A Platform for Synthesizing Diverse α-Functionalized Amines. Shi, Y.; Wang, J.; Yang, F.; Wang, C.; Zhang, X.;* Chiu, P.; Yin, Q.* Chem. Commun. 2022, 58, 513-516. doi: 10.1039/D1CC06601C Copper-catalyzed Reductive Ireland-Claisen Rearrangements of Propargylic Acrylates and Allylic Allenoates. Guo, S.; Wong, K. C.; Scheeff, S.; He, Z.; Chan, W. T. K.; Low, K.-H.; Chiu, P.* J. Org. Chem. 2022, 87, 429-452. doi.org/10.1021/acs.joc.1c02455 Copper-Catalyzed Enantioselective 1,2-Reduction of Cycloalkenones. Shi, Y. J.; Wang, J. X.; Yin, Q.; Zhang, X. M.*; Chiu, P.* Org. Lett. 2021, 23, 5658-5663. doi: 10.1021/acs.orglett.1c01744 Pyrroles as Dienes in (4+3) Cycloadditions. Hu, F.; Ng, J. P. L.; Chiu, P.* Synthesis. 2019, 51, 1073-1086. doi: 10.1055/s-0037-1611660 Applications of (4+3) Cycloadditions in Natural Product Synthesis. Yin, Z. S.; He, Y.; Chiu, P.* Chem. Soc. Rev. 2018, 47, 8881-8924. DOI: 10.1039/C8CS00532J. Part of the themed collection: New Directions in Natural Product Synthesis. Intramolecular (4+3) Cycloadditions of Pyrroles and Application to the Synthesis of Class II Galbulimima Alkaloids. He, J.; Chen, Z.; Li, W.; Low, K.H.; Chiu, P.* Angew. Chem. Int. Ed. 2018, 57, 5253-5256. doi: 10.1002/anie.201711439 Synthesis and Applications of Unquaternized C-bound Boron Enolates. Ng., E. W. H.; Low, K.H.; Chiu, P.* J. Am. Chem. Soc. 2018, 140, 3537-3541. doi:10.1021/jacs.8b00614 Application of a Rhodium-catalyzed Cyclization Cycloaddition Cascade Strategy to the Total Synthesis of (-)-Curcumol. Zhang, X. X.;* Ko, R. Y. Y.; Xie, X. Q.; Qi, W. P.; Li, P. C.; Chiu, P.* Org. Chem. Front., 2018, 5, 1092-1095. doi: 10.1039/C7QO01150D Transannular [4+3] Cycloadditions of Macrocyclic Epoxy Ketones. Chan, D.; Chen, Y.; Low, K. H.; Chiu, P.* Chem.-Eur. J. 2018, 24, 2375-2378. doi: 10.1002/chem.201800019/full ​ An Approach to the Welwistatin Core via a Diazoketone Rearrangement–Ring Expansion Strategy. Lam. S. M.; Wong, W. T.; Chiu, P.* Org. Lett. 2017, 19, 4468–4471. DOI: 10.1021/acs.orglett.7b01988 ​Rearrangements of α-Diazo-β-Hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones. Li, Z.; Lam, S. M.; Ip, I.; Wong, W. T.; Chiu, P.* Org. Lett. 2017, 19, 4464–4467. DOI: 10.1021/acs.orglett.7b01963 A Natural Product-like JAK2/STAT3 Inhibitor Induces Apoptosis of Malignant Melanoma Cells. Wu, K. J.; Huang J. M.; Zhong, H. J.; Dong Z. Z.; Liu, C.; Lu, J.-J.; Chen, X. P.; Chiu, P; Kwong, D. W.; Han, Q. B.; Ma, D. L.*; Leung, C. H.* PLoS One, 2017, 12(6) e0177123. DOI: 10.1371/journal.pone.0177123 Dearomative Intramolecular (4+3) Cycloadditions of Arenes with Epoxy and Aziridinyl Enolsilanes. Ling, J.; Lam, S.; Low, K.-H.; Chiu, P.* Angew. Chem., Int. Ed. 2017, 56, 8879–8882. DOI: 10.1002/anie.201704155 Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms. Wong, V. K. W.; Zeng, W.; Chen J.; Yao, X. J.; Leung, E. L.; Wang Q. Q.; Chiu, P.*; Ko, B. C. B.*; Law, B. Y. K.* Front. Pharmacol. 2017, 8:351. DOI: 10.3389/fphar.2017.00351 3-Quinuclidinol. First Update. Y. Chen, Chiu, P.* In: Electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). John Wiley & Sons, 2016. "Goldilocks Effect" of Water in Lewis-Brønsted Acid and Base Catalysis. Barron, B. J.; Wong, W. T.; Chiu, P.; Hii, K. K.* ACS Catalysis. 2016, 6, 4189–4194. DOI: 10.1021/acscatal.6b00800 Epoxy and Aziridinyl Enolsilanes in Diastereoselective Inter- and Intramolecular Friedel–Crafts Alkylations. Ling, J.; Lam, S. K.; Lo, B.; Lam, S.; Wong, W. T.; Chen, G.; Sun, J.; Chiu, P.* Org. Chem. Front. 2016, 3, 457–461. DOI: 10.1039/C5QO00333D.This article is selected to be in the themed collection: Hot articles in Organic Chemistry Frontiers in 2016. Copper Hydride-Catalyzed Reductive Claisen Rearrangements. Wong, K. C.; Ng, E.; Wong, W. T.; Chiu, P.* Chem. – Eur. J. 2016, 22, 3709–3712. DOI: 10.1002/chem.201504870. This article is part of a Special Issue: Women in Chemistry. Rearrangements of α-Diazo-β-Hydroxyketones for the Synthesis of Bicyclo[m.n.1]alkanones. Li, Z.; Lam, S. M.; Ip, I.; Wong, W. T.; Chiu, P.* Org. Lett. 2017, 19, 4464–4467. DOI: 10.1021/acs.orglett.7b01963 A Natural Product-like JAK2/STAT3 Inhibitor Induces Apoptosis of Malignant Melanoma Cells. Wu, K. J.; Huang J. M.; Zhong, H. J.; Dong Z. Z.; Liu, C.; Lu, J.-J.; Chen, X. P.; Chiu, P; Kwong, D. W.; Han, Q. B.; Ma, D. L.*; Leung, C. H.* PLoS One, 2017, 12(6) e0177123. DOI: 10.1371/journal.pone.0177123 Dearomative Intramolecular (4+3) Cycloadditions of Arenes with Epoxy and Aziridinyl Enolsilanes. Ling, J.; Lam, S.; Low, K.-H.; Chiu, P.* Angew. Chem., Int. Ed. 2017, 56, 8879–8882. DOI: 10.1002/anie.201704155 Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms. Wong, V. K. W.; Zeng, W.; Chen J.; Yao, X. J.; Leung, E. L.; Wang Q. Q.; Chiu, P.*; Ko, B. C. B.*; Law, B. Y. K.* Front. Pharmacol. 2017, 8:351. DOI: 10.3389/fphar.2017.00351