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个人简介

高利霞,理学博士。浙江大学医学院系统神经与认知科学研究所研究员,听觉的感知和认识实验室课题组长,博士生导师,浙大第二附属医院双聘教授。2000年本科毕业于内蒙古大学生命科学学院,2004年硕士毕业于华东师范大学生命科学学院脑功能基因组实验室,导师孙心德教授。2009年博士毕业于中科院神经所,导师蒲慕明教授。随后相继在香港理工大学贺菊芳教授实验室(2009-2011)和美国约翰霍普金斯大学王小勤教授实验室(2011-2016)做博士后研究。在JHU工作期间,她建立了在清醒狨猴听皮层进行尖电极细胞内记录的方法,并利用该方法研究听皮层神经元对节律声、复杂声编码的阈下神经机制。研究工作分别发表在《Neuron》,《Nature Protocol》,《Cerebral Cortex》, 《Advanced Materials》《Journal of Neuroscience》,《Neuroscience》, 《Neuroscience Bulletin》等神经科学领域的核心期刊上。2017年初以人才引进形式受聘于浙大,目前,高利霞实验室主要以非人灵长类动物狨猴为研究对象,采用行为学,电生理学以及现代分子生物学等方法来研究狨猴的叫声发育、叫声交流,清醒狨猴听觉编码以及自闭症,抑郁症狨猴模型的构建和脑神经环路机制研究。

研究领域

语言和音乐等复杂声编码 狨猴叫声发育和叫声交流 狨猴疾病模型和神经环路研究

近期论文

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Zhe Feng#, Siyi Bai#, Ji Qi#, Chaowei Sun, Yuhuang Zhang, Xiaoming Yu, Huwei Ni, Di Wu, Xiaoxiao Fan, Dingwei Xue, Shunjie Liu, Ming Chen, Junyi Gong, Peifa Wei, Mubin He, Jacky W. Y. Lam, Xinjian Li, Ben Zhong Tang*, Lixia Gao*, Jun Qian*,Biologically excretable AIE dots for visualizing through the marmosets intravitally: horizons in future clinical nanomedicine,Advanced Materials, 2021 Mar 19;e2008123. doi: 10.1002/adma.202008123 (IF 27) Lixia Gao* and Xiaoqin Wang, Intracellular neuronal recording in awake nonhuman primates. Nature Protocol, 2020 Oct, doi:10.1038/s41596-020-0388-3, Impact Factor 10.4, *First and corresponding authors Lixia Gao*, Yuanqing Zhang, Xinjian Li, Jufang He, Enhancement of Neuronal Activity in the Auditory Thalamus after Simulated Slow-Wave Oscillation, Neuroscience Bulletin, 2020 Jul; 36(7):806-810. doi: 10.1007/s12264-020-00487-6. Epub 2020 Mar 21. 2020, Impact Factor 4.6, *First and corresponding authors Lixia Gao* and Xiaoqin Wang, Subthreshold Activity Underlying the Diversity and Selectivity of the Primary Auditory Cortex Studied by Intracellular Recordings in Awake Marmosets, Cerebral Cortex, 2019 Mar 1; 29(3):994-1005, doi: 10.1093/cercor/bhy006. 2018,Impact Factor 6.6 , *First and corresponding authors Lixia Gao*, Xinjian Li, Wenwei Yang, Xinde Sun, Modulation of the azimuth tuning plasticity in rat primary auditory cortex by medial prefrontal cortex, Neuroscience, 2017 Apr 7;347:36-47, doi: 10.1016/j.neuroscience.2017.01.046. Epub 2017 Feb 8. Impact Factor 3. *First and corresponding authors Lixia Gao, Kevin Kostlan, Yunyan Wang and Xiaoqin Wang , Distinct Subthreshold Mechanisms Underlying Rate-Coding Principles in Primate Auditory Cortex. Neuron, 91 (4): 905-919, 2016, doi: 10.1016/j.neuron.2016.07.004, Epub 2016 Jul 28. Impact Factor 16, Citation index 1, Cover paper. Lixia Gao, Xiankai Meng, Yang Dan, Muming Poo, Jufang He, Xiaohui Zhang, Entrainment of slow oscillations of auditory thalamic neurons by repetitive sound stimuli J. Neurosci. 29(18): 6023-6031, 2009, doi: 10.1523/JNEUROSCI.5733-08.2009, Impact Factor 7, Citation index 29 Lixia Gao, Fei Gao, Xinde Sun, Effects of lead on learning and memory. Biology Teaching, 2004 (6), 2004. Wenwei Yang, Lixia Gao, Xinde Sun, Receptive field plasticity of neurons in rat auditory cortex. Chinese Science Bulletin 49 (13): 1364-1369, 2004. Impact Factor 1.4, Citation index 8

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