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个人简介

教育背景: 2005年 6月 本科毕业于浙江大学信息与电子工程学系; 2005年 9月 保送浙江大学信息与电子工程学系研究生; 2010年12月 博士毕业于新加坡国立大学(NUS)综合科学与工程研究生院(NGS),导师为共聚焦显微镜的奠基者之一 Colin J. R. Sheppard 教授。

研究领域

读脑(光学显微成像),控脑(光遗传学),数字诊疗,人工智能

近期论文

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C. Wu; J. Chen; B. Zhang; Y. Zheng; X. Zhu; K. Si and W. Gong, Multiple guide stars optimization in conjugate adaptive optics for deep tissue imaging, Optics Communications, (accepted) L. Hu, S. Hu, W. Gong, and K. Si, Learning-based Shack-Hartmann wavefront sensor for high-order aberration detection, Optics Express, 27(23), 33504-33517 (2019) S. Hu, L. Hu, B. Zhang, W. Gong and K. SI, Simplifying the detection of optical distortions by machine learning, Journal of Innovative Optical Health Sciences, (accepted) L. Hu, S. Hu, Y. Li, W. Gong and K. Si, Reliability of wavefront shaping based on coherent optical adaptive technique in deep tissue focusing, Journal of Biophotonics, (accepted) C. Jian, K. Si, C. Ma et.al, Streak artifacts suppression in photoacoustic computed tomography using adaptive back projection, Biomedical Optics Express,10(9), 4803-4814, (2019) C. Wu, J. Chen, K. Si*, Y. Song, X. Zhu, L. Hu,Y. Zheng, and W. Gong*,Aberration corrections of doughnut beam by adaptive optics in the turbid medium, Journal of Biophotonics, https://doi.org/10.1002/jbio.201900125, ( 2019) C. Cai, X. Wang, K. Si, J. Qian, J. Luo, C. Ma, feature coupling photoacoustic computed tomography for joint reconstruction of initial pressure and sound speed in vivo, Biomedical Optics Express, 10(7), 3447-3462 (2019) Y. Zhang, C. Wu, Y. Song, K. SI, Y. Zheng, L. Hu, J. Chen, L. Tang, and W. Gong, Machine learning based adaptive optics fordoughnut-shaped beam, Optics Express, 27, 16871-16881 (2019) X. Zhu, L. Huang, Y. Zheng, J. Wang, Y. Song, Q. Xu, K. Si*, S. Duan, and W.Gong*, Ultrafast Optical Clearing Method for Three-dimensional Imaging withCellular Resolution, PNAS, 116(23), doi: 10.1073/pnas.1819583116 (2019). B. Zhang, C. Wu, L. Hu, W. Gong, X. Zhu and K. Si*, Corrective phasedetermination method for multidither coherent optical adaptive technique in two-photon microscopy, Journal of Innovative Optical Health Sciences, 1942003 (2019). K. Si*, Y. Zhang, Y. Jin, L. Hu, W. Gong, Deep tissue focusing based on machinelearning, Proceedings of SPIE, 11023, 1102340 (2019). C. Wu, Y. Zheng, L. Hu, J. Wang, W. Gong*, & K. Si*, Improvements withdivided cosine-shaped apertures in confocal microscopy, Optics Communications, 442, 71-76 (2019). Y. Zheng, J. Chen, X. Shi, et al. Two photon focal modulation microscopy for high-resolution imaging in deep tissue, Journal of Biophotonics, 12(1), e201800247 (2019). Q. Zhao, X. Shi, X. Zhu, et al. Large field-of-view correction by using conjugate adaptive optics with multiple guide stars, Journal of Biophotonics, 12(2), e201800225 (2019). K. Si*, X. Shi, Q. Zhao, L. Hu, & W. Gong, Deep fluorescent imaging with largefield of view using automatic guide star selection, Proceedings of SPIE, 10964,109645H (2018). Y. Jin, Y. Zhang, L. Hu, H. Huang, Q. Xu, X. Zhu, L. Huang, Y. Zheng, H. Shen, W. Gong and K. Si, Machine learning guided rapid focusing with sensor-less aberration corrections, Optics Express, 26(23), 30162-30171(2018) Yang Yu, Jiahao Wang, Chan Way Ng, Yukun Ma, Shupei Mo, Eliza Li Shan Fong, Jiangwa Xing, Ziwei Song, Yufei Xie, Ke Si, Aileen Wee, Roy E. Welsch, Peter So, and Hanry Yu, Deep learning enables automated scoring of liver fibrosis stages, Scientific Reports 8(1),16016(2018). H. Tang, C. Wu, W. Gong*, Y. Zheng, X. Zhu, J. Wang, & K. Si*, Optimization for imaging through scattering media for confocal microscopes with divided elliptical apertures, Journal of Biophotonics, 11(5), e201700293 (2018). Q. Zhao, X. Shi, W. Gong, et al. Parallel Wavefront Correction for Large Field-of-view Deep Tissue Optical Imaging, Chinese Laser, accepted (2018). X. Wang, J. Wang, X. Zhu, Y. Zheng, K. Si, & W. Gong*, Super-resolution microscopy and its applications in neuroscience, Journal of Innovative Optical Health Sciences, 10(5), 1-11.(2017). X. Zhu, Y. Xia, X. Wang, K. Si, &, W. Gong*, Optical Brain Imaging: A Powerful Tool for Neuroscience, Neuroscience Bulletin, 33(1), 95-102 (2017). S. Shen, B. Zhu, Y. Zheng, W. Gong*, & K. Si, Stripe-shaped apertures in confocal microscopy, Applied Optics, 55(27), 7613-7618 (2016). B. Zhu, S. Shen, Y. Zheng, W. Gong*, & K Si, Numerical studies of focal modulation microscopy in high-NA system, Optics Express, 24(17), 19138-19147 (2016). K. Si, Y. Xu, Y. Zheng, X. Zhu, W. Gong*, Opto-ultrasound imaging in vivo in deep tissue. (Vol.679, pp.012058) (2016). Y. Ma, C. Kuang*, W. Gong, L. Xue, Y. Zheng, Y. Wang, K. Si*, X. Liu,Improvements of axial resolution in confocal microscopy with fan-shaped apertures, Applied Optics, 54(6): 1354-1362 (2015). K. Si, R. Fiolka, and M, cui, “Breaking the spatial resolution barrier via iterative sound-light interaction in deep tissue microscopy,” Scientific Reports 2, 748; DOI:10.1038/srep00749 (2012). K. Si, R. Fiolka, and M. Cui, “Fluorescence imaging beyond ballistic regime by ultrasound pulse guided digital phase conjugation,” Nature Photonics 6, 657-661 (2012). R. Fiolka, K. Si, and M. Cui, “Parallel wavefront measurements in ultrasound pulse guided digital phase conjugation,” Opt. Express, 20, 24827-24834 (2012). R. Fiolka, K. Si, and M. Cui, “Complex wavefront corrections for deep tissue focusing using low coherence backscattered light,” Opt. Express, 20, 16532-16543 (2012). K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Two photon focal modulation microscopy in turbid media,” Appl. Phys. Lett., 99, 233702 - 233702-3 (2011). K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Enhanced background rejection in thick tissue using focal modulation microscopy with quadrant apertures,” Opt. Commun. 284, 1475-1480 (2011). C. J. R. Sheppard, W. Gong, and K. Si, “Polarization effects in 4Pi Microscopy,” Micron, 42, 353-359 (2011). W. Gong, K. Si, N. Chen, and C. J. R. Sheppard, “Focal modulation microscopy with annular apertures: A numerical study,” J. Biophoton. 3, 476-484 (2010). (Invited paper) W. Gong, K. Si, and C. J. R. Sheppard, “Divided-aperture technique for fluorescence confocal microscopy through scattering media,” Appl. Opt. 49, 752-757 (2010). K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Edge enhancement for in-phase focal modulation microscope,” Appl. Opt. 48, 6290-6295 (2009). K. Si, W. Gong, and C. J. R. Sheppard, “Three-dimensional coherent transfer function for a confocal microscope with two D-shaped pupils,” Appl. Opt. 48, 810-817 (2009). K. Si, W. Gong, and C. J. R. Sheppard, “Model for light scattering in biological tissue and cells based on random rough nonspherical particles”, Appl. Opt. 48, 1153-1157 (2009). W. Gong, K. Si, N. Chen, and C. J. R. Sheppard, “Improved spatial resolution in fluorescence focal modulation microscopy,” Opt. Lett. 34, 3508-3510 (2009). W. Gong, K. Si, and C. J. R. Sheppard, “Optimization of axial resolution in confocal microscope with D-shaped apertures,” Appl. Opt. 48, 3998-4002 (2009). W. Gong, K. Si, and C. J. R. Sheppard, “Improvements in confocal microscopy imaging using serrated divided apertures,” Opt. Commun. 282, 3846-3849 (2009). W. Gong, K. Si, and C. J. R. Sheppard. “Modeling phase functions in biological tissue,” Opt. Lett. 33, 1599-1601 (2008). C. J. R. Sheppard, W. Gong, and K. Si, “The divided aperture technique for microscopy through scattering media,” Opt. Express, 16, 17031–17038 (2008). K. Si, W. Gong, C. C. Kong, and Teoh Swee-Hin, “Visualization of bone material map with novel material sensitive transfer functions,” J. Biomechanical Science and Engineering, 2, S211 (2007). W. Gong, K. Si, and C. J. R. Sheppard, “Light scattering by random non-spherical particles with rough surface in biological tissue and cells,” J. Biomechanical Science and Engineering, 2, S171 (2007). W. Gong, K. Si, X. Q. Ye, and W. K. Gu, “A highly robust real-time image enhancement,” Chinese Journal of Sensors and Actuators, 9, 58-62 (2007). W. Gong, N. Chen, and C. J. R. Sheppard, K. Si, “Image formation of two-photon focal modulation microscopy,” Imaging & Applied Optics: OSA Optics and Photonics Congress, (2013). W. Gong, and K. Si, “Two-photon fluorescence microscopy with ultrasound guided digital phase conjugation,” Imaging & Applied Optics: OSA Optics and Photonics Congress, (2013). M. Cui, R. Fiolka, and K. Si, “Fluorescence microscopy beyond the ballistic regime using ultrasound guided digital phase conjugation,” Frontiers in Optics 2012 / Laser science XXVIII, (2012). R. Fiolka, K. Si, and M. Cui, “Diffraction limited and light efficient deep tissue imaging by iterative multiphoton compensation technique (IMPACT),” Photonics West, (2012). C. J. R. Sheppard, K. Si, W. Gong, and N. G. Chen, “Two-photon Focal Modulation Microscopy,” Focus on Microscopy, (2011) K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Imaging Formation of Scattering Media by Focal Modulation Microscopy with Annular Apertures,” SPIE Photonics Europe, (2010). K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Annular pupil focal modulation microscopy,” Focus on Microscopy, (2010). K. Si, W. Gong, N. Chen, and C. J. R. Sheppard, “Focal Modulation Microscopy with Annular Apertures,” 2nd NGS Student symposium, (2010). W. Gong, K. Si, N. Chen, and C. J. R. Sheppard, “Two photon focal modulation microscopy,” Focus on Microscopy, (2010). W. Gong, K. Si, N. Chen, and C. J. R. Sheppard, “Two-photon microscopy with simultaneous standard and enhanced imaging performance using focal modulation technique,” SPIE Photonics Europe, (2010). C. J. R. Sheppard, W. Gong, K. Si, C. H. Wong, S. P. Chong, and N. G. Chen, “Optical Imaging into Biological Tissue and Cells,” ICOP 2009- International Conference on Optics and Photonics, (2009). K. Si, W. Gong, and C. J. R. Sheppard, “Modulation Confocal Microscope with Large Penetration Depth”, SPIE Photonics West, (2009). K. Si, W. Gong, and C. J. R. Sheppard, “Better Background Rejection in Focal Modulation Microscopy,” OSA Frontiers in Optics (FiO)/Laser Science XXV (LS) Conference, (2009). K. Si, W. Gong, and C. J. R. Sheppard, “Fractal Characterization of Biological Tissue with Structure Function,” the Seventh Asian-Pacific Conference on Medical and Biological Engineering (APCMBE 2008). K. Si, W. Gong, and C. J. R. Sheppard, “Application of Random Rough Nonspherical Particles Mode in Light Scattering in Biological Cells,” GPBE/NUS-TOHOKU Graduate Student Conference in Bioengineering, (2008). K. Si, W. Gong, and C. J. R. Sheppard, “3D Fractal Model for Scattering in Biological Tissue and Cells,” 5th International Symposium on Nanomanufacturing, (2008). K. Si, W. Gong, C. C. Kong, and T. S. Hin, “Visualization of Bone Material with Novel Material Sensitive Transfer Functions,” Third Asian Pacific Conference on Biomechanics, (2007). W. Gong, K. Si, and C. J. R. Sheppard, “Light Scattering by Random Non-spherical Particles with Rough Surface in Biological Tissue and Cells,” Third Asian Pacific Conference on Biomechanics, (2007). W. Gong, K. Si, and C. J. R. Sheppard, “Light Scattering by Random Non-spherical Particles with Rough Surfaces in Biological Tissue and Cells,” The 4th Scientific Meeting of the Biomedical Engineering Society of Singapore (2007). K. Si, W. Gong, C. C. Kong, and Teoh. Swee-Hin, “Application of Novel Material Sensitive Transfer Function in Characterizing Bone Material Properties,” The 4th Scientific Meeting of the Biomedical Engineering Society of Singapore (2007).

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