Fajardo, Jacqueline - University of Delaware - Department of Chemistry & Biochemistry

研究领域

My work centers on the CHEM103/104 General Chemistry series. The traditional version of these courses comprise of science and engineering students who do not have a major emphasis in chemistry or chemical engineering, yet require a strong foundation in chemistry on which to build upon. I strive to foster a continuous learning environment so that, through their experiences in lecture, laboratory, workshop, and unscheduled time in between, our students are immersed in the study of chemistry. This immersion requires careful implementation and utilization of numerous instructional and technological resources available here at UDel. To access my students unscheduled time, all of my course lectures, both in-class and supplemental, are posted directly to our course site. Supplemental recorded lectures give me the freedom to spend our precious lecture time engaging in dialogue with the students, developing ideas, queries, and furthering our collective insights. Methods of simple problem solving, such as techniques associated with dimensional analysis, are addressed through supplemental lectures that may be viewed by the students at their own convenience, and applied during lecture. My initial scientific experiences as an undergraduate researcher profoundly influenced and shaped my current view on the importance of undergraduate education. I was fascinated with protein structure and I wanted to understand how such complex beauty could have been achieved. I immersed myself in the study of protein structure using x-ray crystallography as a tool. A notable achievement was my solved structure of a cytotoxic protein from E. coli, Colicin B (55 kDa), which we discovered consisted of a 75 Å long helical linkage between two distinct N- and C-terminal regions. Using my skills in x-ray crystallography and protein structure, I migrated to the world of chemical education as a means to share my knowledge and discoveries with students just beginning their journey into science and chemistry. My dissertation research established the concept of scale transfer in biochemical education research, and through this research, I recognized that transfer between different contexts could also be applied to transfer between scales, and misconceptions that were previously undetected could be elucidated.

近期论文

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Wasacz, J., Fajardo, J. & Suits, J. (2006) Online collaborative learning in a science laboratory course: Student-generated inferences and misconceptions. In E. Pearson & P. Bohman (Eds.), Proceedings of World Conference on Educational Multimedia, Hypermedia and Telecommunications, pp. 1336-1343. Hilsenbeck (Fajardo) JL, Park H, Chen G, Youn B, Postle K, Kang C. (2004) Crystal structure of the cytotoxic bacterial protein Colicin B at 2.5 A resolution. Mol Microbiol, Vol. 51, No. 3, pp. 711-720. Park H, Hilsenbeck (Fajardo) JL, Kim HJ, Shuttleworth WA, Park YH, Evans JN, Kang C. (2004) Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state. Mol Microbiol. Vol. 51, No. 4, pp. 963-971. Min T, Kasahara H, Bedgar DL, Youn B, Lawrence PK, Gang DR, Halls SC, Park H, Hilsenbeck (Fajardo) JL, Davin LB, Lewis NG, Kang C. (2003) Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J Biol Chem. Vol. 278, No. 50, pp. 50714-50723. Wright DB, Banks DD, Lohman JR, Hilsenbeck (Fajardo) JL, Gloss LM. (2002) The effect of salts on the activity and stability of Escherichia coli and Haloferax volcanii dihydrofolate reductases. J Mol Biol., Vol. 323,No. 2, pp. 327-344. Goheen SC, Gibbins BM, Hilsenbeck (Fajardo) JL and Edwards JV. (2001) Retention, unfolding, and deformation of soluble proteins on solids in Bioactive Fibers and Polymers, ed(s) Edwards JV and Vigo TL. Washington, D.C., Oxford University Press, pp. 20-34. Goheen SC, Hilsenbeck (Fajardo) JL. (1998) High-performance ion-exchange chromatography and adsorption of plasma proteins. J Chromatogr A., Vol. 16, No. 1, pp. 89-96. Erratum, 1998, J Chromatogr A Vol. 824, No. 1, p. 135