Taylor, Erika - Wesleyan University - Department of Chemistry

个人简介

BS University of Michigan PHD University of Illinois Urbana

研究领域

Biological Chemistry: Research focusing on enzyme mechanism determination, gene function assignment, transition-state and mechanism-based inhibitor design, and directed evolution of enzyme function

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Mudapaka, J.#; Taylor, E. A., “Purification and Biochemical Characterization of the HeptosyltransferaseIII from Escherichia coli,” FEBS Letters (3.34 Impact Factor), 2015, in press. Chen, L.; Shukla, N.; Cho, I.; Cohn, E. F.*; Taylor, E. A.; Othon, C. M., “Sucralose Destabilization of Protein Structure,” Journal of Physical Chemistry Letters (6.69 Impact Factor), 2015, 6, 1441-1446. doi: 10.1021/acs.jpclett.5b00442 Barry, K. P.#; Ngu, A.*; Cohn, E. F.*; Cote, J. M.#; Gerbino, J. P. #; Taylor, E. A., “Exploring allosteric activation of LigAB from Sphingobium sp. strain SYK-6 through kinetics, mutagenesis and computational studies,” Archives of Biochemistry and Biophysics (3.04 Impact Factor), 2015, 567, 35-45. doi: 10.1016/j.abb.2014.12.019 Barry, K. P. #; Taylor, E. A., “Characterizing the Promiscuity of LigAB, a Lignin Catabolite Degrading Extradiol Dioxygenase from Sphingomonas paucimobilis SYK-6,” Biochemistry (3.19 Impact Factor), 2013, 52, 6724–6736. doi: 10.1021/bi400665t Czyzyk, D. J.#; Sawant, S.#; Ramirez-Mondragon, C. A. #, Hingorani, M. M.; Taylor, E. A., “Escherichia coli Heptosyltransferase I: Investigation of Protein Dynamics of a GT-B Structural Enzyme,” Biochemistry (3.19 Impact Factor), 2013, 52, 5158-5160. doi: 10.1021/bi400807r Czyzyk, D. J.#; Liu, C.*; Taylor, E. A., “Lipopolysaccharide Biosynthesis without the Lipids: Substrate recognition for Escherichia coli HeptosyltransferaseI,”, Biochemistry (3.19 Impact Factor), 2011, 50, 10570-10572. doi: 10.1021/bi201581b Li, L.; Luo, M.; Ghanem, M.; Taylor, E.A.; Schramm, V.L., “Second-sphere amino acids contribute to transition-state structure in bovine purine nucleoside phosphorylase,” Biochemistry (3.19 Impact Factor), 2008, 47, 2577-83. doi: 10.1021/bi7021365 Taylor, E. A.; Rinaldo-Matthis, A.; Li, L.; Ganhem, M.; Hazleton, K. Z.; Cassera, M. B; Almo, S. C.; Schramm, V. L., “Anopheles gambiae Purine Nucleoside Phosphorylase: Catalysis, Structure and Inhibition,” Biochemistry (3.19 Impact Factor), 2007, 46, 12405-12415. doi: 10.1021/bi7010256 Luo, M.; Singh, V.; Taylor, E. A.; Schramm, V. L., “Transition State Structures of Human, Bovine and Plasmodium falciparum Adenosine Deaminases,” Journal of the American Chemical Society (11.44 Impact Factor), 2007, 129, 8008-8017. Taylor, E. A.; Clinch, K.; Kelly, P. M.; Li, L.; Evans, G. B.; Tyler, P. C.; Schramm, V. L., “Acyclic Ribooxacarbenium Ion Mimics as Transition State Analogues of Human and Malarial Purine Nucleoside Phosphorylases,” Journal of the American Chemical Society (11.44 Impact Factor), 2007, 129, 6984-6985. Taylor Ringia, E. A.; Tyler, P. C.; Evans, G. B.; Furneaux, R. H.; Murkin, A. S.; Schramm, V. L., “Transition State Analogue Discrimination by Related Purine Nucleoside Phosphorylases,” Journal of the American Chemical Society (11.44 Impact Factor), 2006, 128, 7126-7127. Taylor Ringia, E. A.; Schramm, V. L., “Transition States and Inhibitors of the Purine Nucleoside Phosphorylase Family,” Current Topics in Medicinal Chemistry (3.45 Impact Factor), 2005, 5, 1237-1258. Lewandowicz, A; Taylor Ringia, E. A.; Ting, L.-M.; Kim, K; Tyler, P. C.; Evans, G. B.; Zubkova, O. V.; Mee, S.; Painter, G. F.; Lenz, D. H.; Furneaux, R. H.; Schramm, V. L., “Energetic Mapping of Transition State Analogue Interactions with Human and Plasmodium falciparum Purine Nucleoside Phosphorylases,” Journal of Biological Chemistry (4.60 Impact Factor), 2005, 280, 30320-30328. Thoden, J. B.; Taylor Ringia, E. A.; Garrett, J. B.; Gerlt, J. A.; Holden, H. M.; Rayment, I., “Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis,” Biochemistry (3.19 Impact Factor), 2004, 43, 5716-5727. Taylor Ringia, E. A.; Garrett, J. B.; Thoden, J. B.; Holden, H. M.; Rayment, I.; Gerlt, J. A., “Evolution of Enzymatic Activity in the Enolase Superfamily: Functional Studies of the Promiscous o-Succinylbenzoate Synthase from Amycolatopsis,” Biochemistry (3.19 Impact Factor), 2004, 43, 224-229. Klenchin, V. A.; Taylor Ringia, E. A.; Gerlt, J. A.; Rayment, I., “Evolution of Enzymatic Activity in the Enolase Superfamily: Structural and Mutagenic Studies of the Mechanism of the Reaction Catalyzed by o-Succinylbenzoate Synthase from Escherichia coli,” Biochemistry (3.19 Impact Factor), 2003, 42, 14427-14433. Taylor, E. A.; Palmer, D. R. J.; Gerlt, J. A., “The Lesser “Burden Borne” by o-Succinylbenzoate Synthase: An “Easy” Reaction Involving a Carboxylate Carbon Acid,” Journal of the American Chemical Society (11.44 Impact Factor), 2001, 123, 5824-5825.