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个人简介

教育背景 1999年-2003年 北京化工大学材料科学与工程学院 本科 2004年-2006年 忠南国立大学高分子工学系 硕士 2008年-2011年 新加坡国立大学化学与生物分子系 博士 工作经历 2018年-至今 南方科技大学生物医学工程系 副教授 2015年-2017年 斯坦福大学医学院分子影像中心 访问学者 2011年-2018年 新加坡科研局材料工程研究院 研究科学家, PI 荣誉及奖励 2019年 深圳市海外高层次人才B类、广东省优粤人才以及南山区领航人才 2016年 世界分子影像大会Travel Award 2015年 新加坡科技研究局International Fellowship 2013年 新加坡科技研究局年轻研究员职业发展奖 2011年 教育部优秀自费留学生奖学金 2008年 新加坡国立大学校长奖学金 2004年 韩国科技财团优秀外国留学生奖学金 2003年 北京地区高校优秀毕业生

研究领域

新型分子探针与纳米探针的开发及其在生物医学中的应用

近期论文

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Jen-Shyang Ni,† Xun Zhang,† Guang Yang, Tianyi Kang, Xiangwei Lin, Menglei Zha, Yaxi Li, Lidai Wang, Kai Li*. Photoinduced nonadiabatic decay-guided molecularmotor triggers effective photothermal conversion for hyperthermia cancer therapy. Angew. Chem. Int. Ed. 2020, doi: 10.1002/ange.202002516 (†contributed equally). Jen-Shyang Ni,† Tianliang Min,† Yaxi Li, Menglei Zha, Pengfei Zhang, Chun Loong Ho, Kai Li.* Planar AIEgens with Enhanced Solid-State Luminescence and ROS-Generation for Multidrug-Resistant Bacteria Treatment. Angew. Chem. Int. Ed. 2020, doi: 10.1002/anie.202001103 (†contributed equally). Jen-Shyang Ni,† Yaxi Li,† Wentong Yue, Bin Liu,* Kai Li.* Nanoparticle-based cell trackers for biomedical applications. Theranostics 2020, 10, 1923-1947. (†contributed equally). Qiyao Li,† Ying Li,† Tianliang Min,† Junyi Gong, Lili Du, David Lee Phillips, Junkai Liu, Jacky W. Y. Lam, Herman H. Y. Sung, Ian D. Williams, Ryan T. K. Kwok, Chun Loong Ho, Kai Li, Jianguo Wang,* Ben Zhong Tang.* Time‐dependent photodynamic therapy for multiple targets: a highly efficient AIE‐active photosensitizer for selective bacterial elimination and cancer cell ablation. Angew. Chem. Int. Ed. 2019, doi: 10.1002/anie.201909706 (†contributed equally). Huaxiao Yang,* Xulei Qin, Huiyuan Wang, Xin Zhao, Yonggang Liu, Hung-Ta Wo, Chun Liu, Masataka Nishiga, Haodong Chen, Jing Ge, Nazish Sayed, Oscar J. Abilez, Dan Ding, Sarah C. Heilshorn, Kai Li.* An in vivo miRNA delivery system for restoring infarcted myocardium. ACS Nano 2019, 13, 9880-9894. Guorui Jin, Rongyan He, Qian Liu, Min Lin, Yuqing Dong, Kai Li, Ben Zhong Tang, Bin Liu, Feng Xu. Near-infrared light-regulated cancer theranostic nanoplatform based on aggregation-induced emission luminogen encapsulated upconversion nanoparticles. Theranostics 2019, 9, 246-264. Xin-Chi Jiang, Jia-Jia Xiang, Hong-Hui Wu, Tian-Yuan Zhang, Dan-Ping Zhang, Qian-Hao Xu, Xiao-Li Huang, Xiang-Lei Kong, Ji-Hong Sun, Yu-Lan Hu, Kai Li, Yasuhiko Tabata, You-Qing Shen, Jian-Qing Gao. Neural stem cells transfected with reactive oxygen species-responsive polyplexes for effective treatment of ischemic stroke. Adv. Mater. 2019, 31, 1807591. Xulei Qin,† Haodong Chen,† Huaxiao Yang,† Haodi Wu, Xin Zhao, Huiyuan Wang, Tony Chour, Evgenios Neofytou, Dan Ding, Heike Daldrup-Link, Sarah C. Heilshorn, Kai Li,* Joseph C. Wu.* Photoacoustic imaging of embryonic stem cell-derived cardiomyocytes in living hearts with ultrasensitive semiconducting polymer nanoparticles. Adv. Funct. Mater. 2018, 28, 1704939 (†contributed equally). Heqi Gao, Xiaoyan Zhang, Chao Chen, Kai Li,* Dan Ding.* Unity makes strength: how aggregation-induced emission luminogens advance the biomedical field. Adv. Biosys. 2018, 2, 1800074 (Invited Review). Kai Li, † Carmel T. Chan, † Hossein Nejadnik, † Olga D. Lenkov, Cody Wolterman, Ramasamy Paulmurugan, Huaxiao Yang, Sanjiv Sam Gambhir, Heike E. Daldrup-Link. Ferumoxytol-based dual-modality imaging probe for detection of stem cell transplant rejection. Nanotheranostics 2018, 2, 306-319 (†contributed equally). Xiang Ni, Shaorui Jia, Xingchen Duan, Dan Ding,* Kai Li.* Fluorescent nanoparticles for noninvasive stem cell tracking in regenerative medicine. J. Biomed. Nanotechnol. 2018, 14, 240-256 (Invited Review). Kai Li,* Hossein Nejadnik, Heike E. Daldrup-Link.* Next generation superparamagnetic iron oxide nanoparticles for cancer theranostics. Drug Discov. Today 2017, 22, 1421-1429 (Invited Review). Guorui Jin, Jun Li, Kai Li.* Photosensitive semiconducting polymer-incorporated nanofibers for promoting the regeneration of skin wound. Mater. Sci. Eng. C 2017, 70, 1176-1181. Suchismita Mohanty, Zixin Chen, Kai Li, Goreti Ribeiro Morais, Jessica Klockow, Ketan Yerneni, Laura Pisani, Frederick T. Chin, Siddhartha Mitra, Samuel Cheshier, Edwin Chang, Sanjiv Sam Gambhir, Jianghong Rao, Paul M. Loadman, Robert A. Falconer, Heike E. Daldrup-Link. A novel theranostic strategy for MMP-14 expressing glioblastomas impacts survival. Mol. Cancer Ther. 2017, 16, 1909-1921. Hossein Nejadnik,† Seyedmeghdad Taghavigarmestani,† Steven Madsen, Kai Li, Saeid Zanganeh, Phillip Yang, Morteza Mahmoudi, Heike E. Daldrup-Link. The protein corona around nanoparticles facilitates stem cell labeling for clinical MRI. Radiology 2017, DOI: 10.1148/radiol.2017170130 (†contributed equally). Guorui Jin, Guangxue Feng, Wei Qin, Ben Zhong Tang, Bin Liu,* Kai Li.* Multifunctional organic nanoparticles with aggregation-induced emission (AIE) characteristics for targeted photodynamic therapy and RNA interference therapy. Chem. Commun. 2016, 52, 2752-2755. Shengjie Peng, Guorui Jin, Linlin Li, Kai Li, Madhavi Srinivasan, Seeram Ramakrishna, Jun Chen. Multi-functional electrospun nanofibres for advances in tissue regeneration, energy conversion & storage, and water treatment. Chem. Soc. Rev. 2016, 45, 1225-1241. Guorui Jin, Duo Mao, Pingqiang Cai, Rongrong Liu, Nikodem Tomczak, Jie Liu, Xiaodong Chen, Deling Kong, Dan Ding,* Bin Liu,* Kai Li.* Conjugated polymer nanodots as ultrastable long-term trackers to understand mesenchymal stem cell therapy in skin regeneration. Adv. Funct. Mater. 2015, 25, 4263-4273 (Frontispiece Story). Jie Liu, Kai Li,* Bin Liu.* Far-red/near-infrared conjugated polymer nanoparticles for long-term in-situ monitoring of liver tumor growth. Adv. Sci. 2015, 2, 1500008. Ghayathri Balasundaram, Chris Jun Hui Ho, Kai Li, Wouter Driessen, U. S. Dinish, Chi Lok Wong, Vasilis Ntziachristos, Bin Liu, Malini Olivo. Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer. Inter. J. Nanomedicine 2015, 10, 387-397.

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